It leads to degeneration of muscles of pharynx, leading to mucosal atrophy and development of webs.
[medicaljoyworks.com]
Histopathology Histologically, webs in patients with Plummer-Vinson syndrome show fibrosis, epithelial atrophy, epithelial hyperplasia, hyperkeratosis, basal cell hyperplasia
[statpearls.com]
Deficiency of iron-dependent oxidative enzymes causes gradual degradation of the pharyngeal muscles which lead to mucosal atrophy and formation of webs.
[ncbi.nlm.nih.gov]