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10 Possible Causes for Atrophy of Shins, Lower Limb Vibratory Sense Decreased, Spasticity - Hyperreflexia

  • Autosomal Dominant Spastic Paraplegia Type 8

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] […] of the shins.[cags.org.ae] Get Update Overview Spastic paraplegia-8 is an autosomal dominant neurologic disorder characterized by adult onset of progressive lower limb spasticity and hyperreflexia resulting[diseaseinfosearch.org]

  • Autosomal Dominant Spastic Paraplegia Type 13

    Hereditary spastic paraplegia 8 (SPG8) is a pure hereditary spastic paraplegia characterized by slowly progressive spastic paraplegia of the lower limbs (i.e., hyperreflexia[ncbi.nlm.nih.gov] […] of the shins.[cags.org.ae] Central Nervous System: lower limb spasticity ankle clonus spastic gait lower limb hyperreflexia extensor plantar responses more Neurologic Peripheral Nervous System: decreased[malacards.org]

  • Autosomal Dominant Spastic Paraplegia Type 19

    […] paraplegia 8 is a neurologic disorder characterized by severe lower limb spasticity and weakness.[cags.org.ae] Diagnosis of SPG is established by the following clinical features 1, 2 : Typical clinical symptoms of spastic gait impairment and neurologic findings of spastic weakness,[centogene.com] […] and hyperreflexia, and bilateral extensor plantar response.[ajnr.org]

  • Autosomal Dominant Spastic Paraplegia Type 38

    Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes more Clinical features from OMIM: 607584 UMLS symptoms related to Spastic Paraplegia[malacards.org] It is mild and is limited to atrophy of the shins in elderly & wheelchair-dependent patients. Peripheral nerves are normal in patients with pure HSP. 38.[slideshare.net] Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterised by progressive spasticity and hyperreflexia[ncbi.nlm.nih.gov]

  • Autosomal Dominant Spastic Paraplegia Type 31

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] It is mild and is limited to atrophy of the shins in elderly & wheelchair-dependent patients. Peripheral nerves are normal in patients with pure HSP. 38.[slideshare.net] limb weakness and spasticity, sphincter dysfunction, decreased vibratory sense at the ankles and with additional manifestations including optical neuropathy, nystagmus, strabismus[mendelian.co]

  • Spastic Paraplegia - Ataxia - Mental Retardation

    These sibs did not have overt spasticity, but had some pyramidal signs, such as hyperreflexia.[findzebra.com] It is mild and is limited to atrophy of the shins in elderly & wheelchair-dependent patients. Peripheral nerves are normal in patients with pure HSP. 38.[slideshare.net] Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia[monarchinitiative.org]

  • Autosomal Recessive Spastic Ataxia Type Charlevoix-Saguenay

    Especially in Japan, sacsin-related ataxia without spasticity and hyperreflexia has been reported [ 9, 11, 12 ].[jneuro.com] Frequency of spinocerebellar ataxia types 1,2,3,6,7 and dentatorubral pallidoluysian atrophy mutations in Korean patients with spinocerebellar ataxia.[e-jmd.org] People with this form of spastic paraplegia can also experience exaggerated reflexes (hyperreflexia) in the arms; speech difficulties (dysarthria); difficulty swallowing ([icdlist.com]

  • Tertiary Syphilis

    […] paresis and hyperreflexia 7,8 occurs months to years after infection 3,4 meningovascular syphilis prodrome of mild clinical features of syphilitic meningitis 4,9 this is[radiopaedia.org] Optic atrophy may occur.[msdmanuals.com] vibratory sense in his lower limbs.[step1.medbullets.com]

  • Spinocerebellar Ataxia with Axonal Neuropathy

    , spasticity Impaired vibration sense CTG expansion 100-250 (15-52 normal range) 13q21 KLHL1AS Spinocerebellar ataxia (SCA9) SCA9 has not yet been characterized. -- -- Spinocerebellar[emedicine.medscape.com] Frequency of spinocerebellar ataxia types 1,2,3,6,7 and dentatorubral pallidoluysian atrophy mutations in Korean patients with spinocerebellar ataxia.[e-jmd.org] sense in the lower limbs Demyelination of the posterior and lateral columns of the spinal cord Dysarthria Extensor plantar responses Gait ataxia Limb ataxia Mixed axonal[datagenno.com]

  • Autosomal Recessive Spinocerebellar Ataxia 3

    Definition A neurologic disorder characterized by cerebellar ataxia, ataxic gait, spasticity, and hyperreflexia.[uniprot.org] Frequency of spinocerebellar ataxia types 1,2,3,6,7 and dentatorubral pallidoluysian atrophy mutations in Korean patients with spinocerebellar ataxia.[e-jmd.org] limbs Decreased lower limb vibratory sense Decreased vibratory sense in lower limbs Decreased vibratory sense in the lower extremities Decreased vibratory sense in the lower[rarediseases.info.nih.gov]