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407 Possible Causes for Atrophy of the Pituitary

  • Malnutrition

    The obese phenotype in leptin-deficient ob/ob mice is also associated with diminished circulating T cells, reduced T cell responses, and lymphoid atrophy [ 40 ].[] Furthermore, the natural ligand of the secretagogue receptor of the pituitary gland, ghrelin, which regulates fat storage and consumption, is directly linked to immune functions[]

  • Dermatitis

    , rebound dermatitis, telangiectasia, striae, and dyspigmentation) to systemic (hypothalamic–pituitary–adrenal axis suppression, growth retardation, and Cushing’s syndrome[] […] welcome alternative to topical corticosteroids, since the chronic use of topical corticosteroids has been associated with numerous adverse effects, ranging from local (skin atrophy[]

  • Atopic Dermatitis

    , rebound dermatitis, telangiectasia, striae, and dyspigmentation) to systemic (hypothalamic–pituitary–adrenal axis suppression, growth retardation, and Cushing’s syndrome[] Local side effects include the development of striae and skin atrophy, while systemic side effects result from suppression of the hypothalamic-pituitary-adrenal axis [ 48[] It is necessary to monitor for cutaneous side effects of TCS including striae, telangiectasias, and atrophy, although they are rare.[]

  • Contact Dermatitis

    In addition to possible increased risk for glaucoma , TCS use may lead to skin atrophy, striae, and potential blockage of the Hypothalamic- Pituitary Axis (HPA) [ 6 ].[]

  • Hypothyroidism

    Because of the nonselective nature of the resulting compressive atrophy and replacement of pituitary tissue by such large tumors, deficiencies of other (one or more) pituitary[] Secondary hypothyroidism is pituitary in origin.[] In dogs, the most common cause of secondary hypothyroidism is destruction of pituitary thyrotrophs by an expanding, space-occupying tumor.[]

  • Psoriasis

    […] skin), or systemic side effects, such as diabetes, hypertension and hypothalamic‐pituitary‐adrenal (HPA) axis suppression ( Gardinal 2009 ; Horn 2010 ).[] Prolonged use of topical corticosteroids may induce local adverse effects, such as cutaneous atrophy (skin thinning) and telangiectasia (small, dilated blood vessels in the[]

  • Liver Cirrhosis

    , and can result from primary gonadal injury or suppression of hypothalamic/pituitary function.[] […] increase in breast fat in overweight people. [13] Hypogonadism, a decrease in male sex hormones may manifest as impotence, infertility, loss of sexual drive, and testicular atrophy[]

  • Hemochromatosis

    Pituitary failure is common and may be the cause of testicular atrophy (shrinkage of the testicles) and loss of sex drive, which occurs frequently.[] Loss of libido, impotence, amenorrhea, testicular atrophy, and sparse body hair result from hypogonadism and impairment of the hypothalamic-pituitary axis by iron deposition[]

  • Familial Hypercholesterolemia

    3 Pilomatrixoma 1 Pitt-Hopkins Syndrome 5 Pitt-Hopkins-like syndrome 2 6 Pituitary Adenoma, Growth Hormone-Secreting 1 Pituitary Dependent Hypercortisolism 1 Pituitary Hormone[] Pigmentary Retinal Dystrophy 12 Pigmented Nodular Adrenocortical Disease, Primary, 1 1 Pigmented Nodular Adrenocortical Disease, Primary, 2 1 Pigmented Paravenous Chorioretinal Atrophy[]

  • Orchitis

    The tunica albugenia forms a barrier against oedema, and the subsequent rise in intratesticular pressure leads to pressure-induced testicular atrophy. 5 Adamopoulos et al.[] 6 studied the effects of mumps orchitis on Leydig cell function and found low testosterone levels, elevated leuteinizing hormone levels and an exaggerated pituitary response[]

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