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407 Possible Causes for Atrophy of the Pituitary

  • Malnutrition

    The obese phenotype in leptin-deficient ob/ob mice is also associated with diminished circulating T cells, reduced T cell responses, and lymphoid atrophy [ 40 ].[doi.org] Furthermore, the natural ligand of the secretagogue receptor of the pituitary gland, ghrelin, which regulates fat storage and consumption, is directly linked to immune functions[doi.org]

  • Dermatitis

    , rebound dermatitis, telangiectasia, striae, and dyspigmentation) to systemic (hypothalamic–pituitary–adrenal axis suppression, growth retardation, and Cushing’s syndrome[doi.org] […] welcome alternative to topical corticosteroids, since the chronic use of topical corticosteroids has been associated with numerous adverse effects, ranging from local (skin atrophy[doi.org]

  • Atopic Dermatitis

    , rebound dermatitis, telangiectasia, striae, and dyspigmentation) to systemic (hypothalamic–pituitary–adrenal axis suppression, growth retardation, and Cushing’s syndrome[doi.org] Local side effects include the development of striae and skin atrophy, while systemic side effects result from suppression of the hypothalamic-pituitary-adrenal axis [ 48[omicsonline.org] It is necessary to monitor for cutaneous side effects of TCS including striae, telangiectasias, and atrophy, although they are rare.[doi.org]

  • Contact Dermatitis

    In addition to possible increased risk for glaucoma , TCS use may lead to skin atrophy, striae, and potential blockage of the Hypothalamic- Pituitary Axis (HPA) [ 6 ].[omicsonline.org]

  • Hypothyroidism

    Because of the nonselective nature of the resulting compressive atrophy and replacement of pituitary tissue by such large tumors, deficiencies of other (one or more) pituitary[web.archive.org] Secondary hypothyroidism is pituitary in origin.[clinicaladvisor.com] In dogs, the most common cause of secondary hypothyroidism is destruction of pituitary thyrotrophs by an expanding, space-occupying tumor.[web.archive.org]

  • Psoriasis

    […] skin), or systemic side effects, such as diabetes, hypertension and hypothalamic‐pituitary‐adrenal (HPA) axis suppression ( Gardinal 2009 ; Horn 2010 ).[doi.org] Prolonged use of topical corticosteroids may induce local adverse effects, such as cutaneous atrophy (skin thinning) and telangiectasia (small, dilated blood vessels in the[doi.org]

  • Liver Cirrhosis

    , and can result from primary gonadal injury or suppression of hypothalamic/pituitary function.[en.wikipedia.org] […] increase in breast fat in overweight people. [13] Hypogonadism, a decrease in male sex hormones may manifest as impotence, infertility, loss of sexual drive, and testicular atrophy[en.wikipedia.org]

  • Hemochromatosis

    Pituitary failure is common and may be the cause of testicular atrophy (shrinkage of the testicles) and loss of sex drive, which occurs frequently.[medbroadcast.com] Loss of libido, impotence, amenorrhea, testicular atrophy, and sparse body hair result from hypogonadism and impairment of the hypothalamic-pituitary axis by iron deposition[clinicaladvisor.com]

  • Familial Hypercholesterolemia

    3 Pilomatrixoma 1 Pitt-Hopkins Syndrome 5 Pitt-Hopkins-like syndrome 2 6 Pituitary Adenoma, Growth Hormone-Secreting 1 Pituitary Dependent Hypercortisolism 1 Pituitary Hormone[preventiongenetics.com] Pigmentary Retinal Dystrophy 12 Pigmented Nodular Adrenocortical Disease, Primary, 1 1 Pigmented Nodular Adrenocortical Disease, Primary, 2 1 Pigmented Paravenous Chorioretinal Atrophy[preventiongenetics.com]

  • Orchitis

    The tunica albugenia forms a barrier against oedema, and the subsequent rise in intratesticular pressure leads to pressure-induced testicular atrophy. 5 Adamopoulos et al.[ncbi.nlm.nih.gov] 6 studied the effects of mumps orchitis on Leydig cell function and found low testosterone levels, elevated leuteinizing hormone levels and an exaggerated pituitary response[ncbi.nlm.nih.gov]

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