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11 Possible Causes for Auditory Hallucination, Decreased Platelet Count, Mean Corpuscular Volume Increased

  • Multiple Myeloma

    Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com] Patients may also have: Anemia (low red blood cell count) Leukopenia (low white blood cell count) Thrombocytopenia (low platelet count) Hypercalcemia (high calcium level in[orthoinfo.aaos.org]

  • Vitamin B12 Deficiency

    Hematological presentation of cobalamin deficiency ranges from the incidental increase of mean corpuscular volume and neutrophil hypersegmentation to symptoms due to severe[ncbi.nlm.nih.gov] […] and visual hallucinations the so called megaloblastic madness have been described with vitamin B-12 deficiency.[ispub.com] Other laboratory findings associated with megaloblastic anemia include decreased white blood cell (WBC) count and platelet count.[labtestsonline.org]

  • Chronic Alcoholism

    Serum electrolytes, mean corpuscular volume (MCV) and serum uric acid levels are also indicative of ALD in combination with results from other tests.[hopkinsmedicine.org] “The phenomenon of auditory hallucinations in chronic alcoholism.” J. nerv. ment. Dis., 126, 451. De Wardener, H. E., and Lennox, B. ( 1947 ).[bjp.rcpsych.org] FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info]

  • Pernicious Anemia

    Diagnostic methods Diagnosis depends on blood tests that show low serum levels of cobalamin and megaloblastic anemia (decreased red blood cell count and increased mean corpuscular[orpha.net] […] and visual hallucinations the so called megaloblastic madness have been described with vitamin B-12 deficiency.[ispub.com] RBC and WBC counts are low. Platelet count is low. Red blood cell indices are usually normal.[labtestsonline.org]

  • Megaloblastic Anemia

    Neuropsychiatric manifestation include memory loss, depression, hypomania, paranoid psychosis with auditory and visual hallucinations.[allaboutblood.com] Physicians caring for patients who receive low-dose methotrexate should be aware that an increase in the erythrocyte mean corpuscular volume may be a useful indicator of folate[ncbi.nlm.nih.gov] The platelet count may be reduced. Neutrophil granulocytes may show multisegmented nuclei ("senile neutrophil").[en.wikipedia.org]

  • Congenital Intrinsic Factor Deficiency

    Diagnostic methods Diagnosis depends on blood tests that show low serum levels of cobalamin and megaloblastic anemia (decreased red blood cell count and increased mean corpuscular[orpha.net] […] and visual hallucinations the so called megaloblastic madness have been described with vitamin B-12 deficiency.[ispub.com] Vit.B12 is given parenterally at a dose of 1mg- followup shows decrease in MCV,reticulocytosis and improvement in platelet and neutrophil counts.[slideshare.net]

  • Cerebral Malaria

    A self-limiting psychosis characterized by visual and auditory hallucinations with or without aggressive behavior developed in two children 4 to 5 days after complete recovery[ncbi.nlm.nih.gov] The third independent MRI predictor, predominantly posterior involvement, was associated with an increased white-cell count and a decreased platelet count and with three EEG[doi.org] decrease in peripheral platelet counts.[embopress.org]

  • Anemia

    (MCV mean corpuscular volume.) An Hgb increase of more than 1 g per dL (10 g per L) after iron therapy has been started confirms the diagnosis of iron deficiency.[aafp.org] […] or visual hallucinations (megaloblastic madness), violent behavior, personality changes, blunted affect, and emotional liability, were reported in 8% of patients.[web.archive.org] Some decrease in factors V and VII is noted in comparison with whole blood. Each unit of platelets raises the platelet count by approximately 10,000/µL.[emedicine.com]

  • Homocystinuria

    On follow-up after 3 months of treatment, the power was normal in the limbs, hemoglobin was 14 gm%, mean corpuscular volume decreased to 88.7 fL, mean corpuscular haemoglobin[pediatricneurosciences.com] We describe a previously well 17-year-old adolescent with an acute psychosis characterized by auditory and visual hallucinations and marked paranoia who was found to have[ncbi.nlm.nih.gov] The platelet count increased to 180 Χ 10΃/μL. The serum homocysteine level was 52 μmol/L (normal range, 4.60-12.44).[pediatricneurosciences.com]

  • Hydroxyurea

    Special considerations • Dosage may need to be adjusted after other chemotherapy or radiation therapy. • Auditory and visual hallucinations and blood toxicity increase when[glowm.com] Blood urea nitrogen, creatinine, uric acid: increased values Hemoglobin, platelets, red blood cells, white blood cells: decreased values Mean corpuscular volume: transient[medical-dictionary.thefreedictionary.com] Decreased platelet counts ( 3 ) have occurred rarely and usually in the presence of marked leukopenia.[web.archive.org]

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