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639 Possible Causes for Autosomal Dominant Inheritance Is More Common

  • Gouty Arthritis

    A more common entity is a familial syndrome of hyperuricemia and renal disease with or without gout. This disease is inherited as an autosomal dominant.[pedsinreview.aappublications.org]

  • Hypercholesterolemia

    […] as an autosomal dominant trait with a gene dosage effect—that is, homozygotes are more severely affected than are heterozygotes.[ommbid.mhmedical.com] Heterozygotes number about 1 in 500 persons, placing FH among the most common inborn errors of metabolism.[ommbid.mhmedical.com] […] the major cholesterol-transport lipoprotein in human plasma; (b) deposition of LDL-derived cholesterol in tendons and skin (xanthomas) and in arteries (atheromas); and (c) inheritance[ommbid.mhmedical.com]

  • Ichthyosis Vulgaris

    Ichthyosis vulgaris Epidemiology : most common type of hereditary ichthyosis Etiology : autosomal dominant inheritance ; associated with atopic diseases Clinical presentation[amboss.com] It is the most common form of ichthyosis (it accounts for more than 95% of cases) and it is usually an autosomal dominant inherited disease (although a rare non-heritable[flipper.diff.org] Onset usually between 3 and 12 months of age Lesions Generalized fine, white scaling Dry and coarse skin ( xerosis ): more common on extensor surfaces ( skin folds are usually[amboss.com]

  • Cardiomyopathy

    Sex-related demographics HCM is slightly more common in males than in females. However, the genetic inheritance pattern is autosomal dominant, without sex predilection.[emedicine.medscape.com]

  • Heterozygous Familial Hypercholesterolemia

    […] as an autosomal dominant trait with a gene dosage effect—that is, homozygotes are more severely affected than are heterozygotes.[ommbid.mhmedical.com] […] and autosomal dominant inheritance in 1938. [51] In the early 1970s and 1980s, the genetic cause for FH was described by Dr Joseph L.[en.wikipedia.org] Heterozygotes number about 1 in 500 persons, placing FH among the most common inborn errors of metabolism.[ommbid.mhmedical.com]

  • Hypertrophic Cardiomyopathy

    The genetic inheritance pattern of hypertrophic cardiomyopathy is autosomal dominant so no sex predilection should occur.[symptoma.com] Sex-related demographics HCM is slightly more common in males than in females. However, the genetic inheritance pattern is autosomal dominant, without sex predilection.[emedicine.com] However, it is slightly more common in males than in females. This may be due to other confounding factors.[symptoma.com]

  • Lynch Syndrome

    […] incidence varies from 1 in 7,000 to 1 in 22,000 live births, with the syndrome being more common in Western countries.[ 14 ] Autosomal dominant inheritance means that affected[cancer.gov] FAP is one of the most clearly defined and well understood of the inherited colon cancer syndromes.[ 1 , 12 , 13 ] It is an autosomal dominant condition, and the reported[cancer.gov] Lynch Syndrome Introduction Lynch syndrome is the most common inherited CRC syndrome and accounts for approximately 3% of all newly diagnosed cases of CRC.[cancer.gov]

  • Familial Hypercholesterolemia

    The Norwegian physician Dr Carl Müller first associated the physical signs, high cholesterol levels and autosomal dominant inheritance in 1938.[en.wikipedia.org] APOB mutations are more common in Central Europe.[en.wikipedia.org] The Afrikaner, French Canadians, Lebanese Christians, and Finns have high rates of specific mutations that make FH particularly common in these groups.[en.wikipedia.org]

  • Coxa Vara

    dominant inheritance pattern May be more common in black race Aetiology Histological abnormalities have been found in biopsy of the femoral necks Width of the growth plate[orthopaedicsone.com] Osteoporosis Paget Any age Infection : TB or pyogenic Fracture Children Bone cyst Adult Malunion of fracture NOF Incidence Rare, 1/ 25000 live births M F R L, Bilateral in 30% Autosomal[orthopaedicsone.com]

  • Familial Adenomatous Polyposis

    […] varies from 1 in 7,000 to 1 in 22,000 live births, with the syndrome being more common in Western countries.[ 14 ] Autosomal dominant inheritance means that affected persons[cancer.gov] FAP is one of the most clearly defined and well understood of the inherited colon cancer syndromes.[ 1, 12, 13 ] It is an autosomal dominant condition, and the reported incidence[cancer.gov] Lynch Syndrome Introduction Lynch syndrome is the most common inherited CRC syndrome and accounts for approximately 3% of all newly diagnosed cases of CRC.[cancer.gov]

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