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11 Possible Causes for Average Intelligence, Broad Nasal Bridge, Wide Space Between the First and Second Toe

  • Craniofrontonasal Dysplasia

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] In conclusion, individuals diagnosed with frontonasal dysplasia usually are of average intelligence and can expect a normal life span.[ruralneuropractice.com] […] and broad nasal bridge.[mjdrdypu.org]

  • Down Syndrome

    bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21 — called also trisomy 21 First Known Use of Down syndrome[merriam-webster.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] The intelligence quotient (IQ) among children with Down syndrome varies but averages about 50, compared with normal children, whose average IQ is 100.[merckmanuals.com]

  • Dubowitz Syndrome

    nasal bridge, dysplastic auricles, and retrognathia, is presented.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Results indicate that the level of intellectual functioning among children with Dubowitz syndrome varies from severe retardation to average intelligence.[ncbi.nlm.nih.gov]

  • Ring Chromosome 10

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] Prenatal diagnosis of a female carrier of a familial r(Jeny21) who was of above average intelligence with a normal phenotype; revealed a twin pregnancy with a 46,XX,r(21)[tp.amegroups.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    […] flat nasal bridge, malformed ears, and short neck.[genome.jp] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] […] is often subnormal and, in one study of 15 patients with Apert syndrome, the average IQ was 72.5. 66 Development may be adversely affected by progression of increased intracranial[entokey.com]

  • Genee-Wiedemann Syndrome

    Clinical: Clefts and fibroma of tongue; polydactylia; broad nasal bridge; narrow-arched palate ; short humerus, femur, and tibia; irregular teeth; hypotonia; mental retardation[dentisty.org] He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] They typically have normal intelligence and normal lifespans.[chop.edu]

  • Atelosteogenesis

    The patient had multiple craniofacial abnormalities at birth, including ocular hypertelorism, a flat nasal bridge, micrognathia and a cleft palate.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] They are usually of normal intelligence. Dwarfism most often does happen in families where both parents are of average height.[medlineplus.gov]

  • Macrocephaly-Developmental Delay Syndrome

    nasal bridge, broad cheeks, low-set ears, bilateral and single palmar crease, bilateral clinodactyly of the 5th fingers, overriding toes and hypospadias], persistent nephrogenesis[chr7.org] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] The intelligence quotient according to the Leiter scale equaled 75, which is below the average.[ispub.com]

  • Mild Dysmorphic Features

    Facial dysmorphisms include microcephaly, large ears, bulbous nose, broad nasal bridge, elongated philtrum, and sparse scalp hair.[emedicine.medscape.com] , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com] Some individuals with this microduplication are “normal”- that is, they have average intelligence, no major birth defects, and no major medical illnesses.[c22c.org]

  • MORM Syndrome

    , flat nasal bridge, short neck, low hairline, irregular or wrongly positioned teeth, low-set ears, micrognathia (small jaw), tooth enamel defects, short stature, microcephaly[en.wikipedia.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The average intelligence quotient (IQ) of adult males with the most severe mutation is 40, although those with less severe mutations can have IQs in the borderline to normal[spectrumnews.org]

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