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1,586 Possible Causes for Average Intelligence, Cognitive Developmental Delay, Wide Space Between the First and Second Toe

  • Russell-Silver Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Children with RSS have an increased risk for developmental delay (both motor and cognitive) and learning disabilities.[gemssforschools.org] Furthermore, these developmental deficits and/or delays may contribute towards an emerging clinical presentation of a progressively depressed individual with RSS.[omicsonline.org]

  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] is considered lower than average Can affect boys and girls equally Genetics of Seckel Syndrome Autosomal recessive pattern Additional reading about Seckel Syndrome National[littlepeopleuk.org] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Dubowitz Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The feeding difficulties, developmental and cognitive delay, mottled skin, drug-induced long QT syndrome, short stature, microcephaly, small ears, 2–3 cutaneous syndactyly[journals.plos.org] Results indicate that the level of intellectual functioning among children with Dubowitz syndrome varies from severe retardation to average intelligence.[ncbi.nlm.nih.gov]

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] […] variants: or Down's syndrome Definition of Down syndrome : a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in[merriam-webster.com] The intelligence quotient (IQ) among children with Down syndrome varies but averages about 50, compared with normal children, whose average IQ is 100.[merckmanuals.com]

  • Mucopolysaccharidosis

    It can cause a variety of different effects such as poor motor function, stiffness of joints, laxity of ligaments, cognitive impairment and developmental delays.[manchesterneurophysio.co.uk] Morquio A presents average intelligence, and MPS type VI points to deficits partially related to sensory impairment, implying significant differences between them.[lifescienceglobal.com] In addition to developing somatic symptoms, patients having the neuronopathic form of the disease also display developmental delay and cognitive impairment in early childhood[touchneurology.com]

    Missing: Wide Space Between the First and Second Toe
  • Craniofrontonasal Dysplasia

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] In conclusion, individuals diagnosed with frontonasal dysplasia usually are of average intelligence and can expect a normal life span.[ruralneuropractice.com] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

    Missing: Cognitive Developmental Delay
  • Rolandic Epilepsy

    As with the gabapentin study, many of the children were developmentally delayed or intellectually disabled.[childneurologyfoundation.org] Tiziana Zilli, Sergio Zanini, Stefania Conte, Renato Borgatti and Cosimo Urgesi, Neuropsychological assessment of children with epilepsy and average intelligence using NEPSY[doi.org] RESULT: the obtained data indicate that although intellectual efficiency (measured through the Intelligence Quatient - IQ) was within average, children with rolandic epilepsy[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Craniosynostosis

    Developmental delay is defined as scoring[ncbi.nlm.nih.gov] In some cases, it can lead to developmental delays and cognitive problems, especially if more than one suture is involved.[childrenshospital.org] The Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) was utilized to assess pre- and postoperative cognitive development and comparisons were made[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • SHORT Syndrome

    Developmental milestones and cognition are normal.[uniprot.org] […] to above-average intelligence.[autism-society.org] Although these children may also possess signs of low blood sugar or obesity, they display average body proportions and (average intelligence.[hgfound.org]

    Missing: Wide Space Between the First and Second Toe
  • Mucopolysaccharidosis 4A

    Impaired cognitivity Developmental delay Severe behavioral problems X Hearing loss (conductivity/ neurosensitivity or both) Communicating hydrocephalus (normal absorption[slideshare.net] On clinical examination, the child appeared to have a less than average intelligence but was placid and cooperative.[ijaweb.org] Depending on the mucopolysaccharidosis subtype, affected individuals may have normal intellect or have cognitive impairments, may experience developmental delay, or may have[en.wikipedia.org]

    Missing: Wide Space Between the First and Second Toe