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10 Possible Causes for Average Intelligence, Malocclusion, Wide Space Between the First and Second Toe

  • Down Syndrome

    Dental malocclusion and macroglossia are associated. Technical modifications to increase macroglossia surgery safety and efficacy have been described.[doi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] The intelligence quotient (IQ) among children with Down syndrome varies but averages about 50, compared with normal children, whose average IQ is 100.[merckmanuals.com]

  • Craniofrontonasal Dysplasia

    […] abnormalities including microcephaly, facial asymmetry, palpebral fissures, dry hair and extremely curly, back line of low hair, wide neck, high arched palate, cleft lip and palate, malocclusion[ivami.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] In conclusion, individuals diagnosed with frontonasal dysplasia usually are of average intelligence and can expect a normal life span.[ruralneuropractice.com]

  • Russell-Silver Syndrome

    Though orthodontic treatment may be performed for the malocclusion caused by growth disturbance and right - left asymmetry of viscerocranium, cleft palate is rarely complicated[ci.nii.ac.jp] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Dubowitz Syndrome

    Significant clinical correlation includes: smaU stature, microcephaly, abnormal ears, ptosis, hypertelorism, wide nasal bridge, dental malocclusion, eczema, and mental retardation[healio.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Results indicate that the level of intellectual functioning among children with Dubowitz syndrome varies from severe retardation to average intelligence.[ncbi.nlm.nih.gov]

  • Seckel Syndrome

    Dental findings include hypodontia, enamel hypoplasia, crowding, and Class II malocclusion.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] is considered lower than average Can affect boys and girls equally Genetics of Seckel Syndrome Autosomal recessive pattern Additional reading about Seckel Syndrome National[littlepeopleuk.org]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Nonophthalmic findings in Crouzon syndrome include crowding of the maxillary teeth, lateral palatal swellings, and jaw malocclusion secondary to maxillary hypoplasia. 16 Of[entokey.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] Malocclusion, Angle Class I Malocclusion, Angle Class II Malocclusion, Angle Class III Mammary Neoplasms Mammary Neoplasms, Experimental Mandibular Diseases Mandibular Fractures[medgene.med.harvard.edu]

  • Atelosteogenesis

    Craniofacial abnormalities can lead to dental malocclusion and tongue thrusting.[nature.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] They are usually of normal intelligence. Dwarfism most often does happen in families where both parents are of average height.[medlineplus.gov]

  • Genee-Wiedemann Syndrome

    A case of Angle Class II malocclusion with dental crowding in a growing patient.[reins.tmd.ac.jp] He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] They typically have normal intelligence and normal lifespans.[chop.edu]

  • Mild Dysmorphic Features

    .- ) cyclopia ( Q87.0 ) dentofacial anomalies [including malocclusion] ( M26.- ) malformation syndromes affecting facial appearance ( Q87.0 ) persistent thyroglossal duct[icd10data.com] , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com] Some individuals with this microduplication are “normal”- that is, they have average intelligence, no major birth defects, and no major medical illnesses.[c22c.org]

  • Macrocephaly-Developmental Delay Syndrome

    She also had joints with lax ligaments, a high arched palate, and dental malocclusion (upper front teeth extending over her lower front teeth).[chginc.org] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] The intelligence quotient according to the Leiter scale equaled 75, which is below the average.[ispub.com]

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