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14 Possible Causes for Average Intelligence, Mental Retardation, Wide Space Between the First and Second Toe

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Abstract Although there is considerable variability, most individuals with Down syndrome have mental retardation and speech and language deficits, particularly in language[oadoi.org] The intelligence quotient (IQ) among children with Down syndrome varies but averages about 50, compared with normal children, whose average IQ is 100.[merckmanuals.com]

  • Dubowitz Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] , short stature, microcephaly, mild mental retardation with behavior problems, eczema, and unusual and distinctive faci DUBOWITZ SYNDROME edit English Dubowitz syndrome Human[wikidata.org] Results indicate that the level of intellectual functioning among children with Dubowitz syndrome varies from severe retardation to average intelligence.[ncbi.nlm.nih.gov]

  • Craniofrontonasal Dysplasia

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] In conclusion, individuals diagnosed with frontonasal dysplasia usually are of average intelligence and can expect a normal life span.[ruralneuropractice.com] retardation.[link.springer.com]

  • Russell-Silver Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] At follow-up, five of the 15 patients exhibited late catch-up growth and had normal height, six had developmental delays or mental retardation, and asymmetry was present in[ncbi.nlm.nih.gov] Renal and/or ureteral defects and mental retardation may occur in some cases. Café au lait macules are present in nearly half the cases.[whonamedit.com]

  • Ring Chromosome 10

    […] deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Intrauterine growth retardation Prenatal growth deficiency Prenatal growth[rarediseases.info.nih.gov] Prenatal diagnosis of a female carrier of a familial r(Jeny21) who was of above average intelligence with a normal phenotype; revealed a twin pregnancy with a 46,XX,r(21)[tp.amegroups.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] It is extremely rare and typically causes dwarfism, mental retardation, intrauterine growth retardation and microcephaly.[symptoma.com] […] is considered lower than average Can affect boys and girls equally Genetics of Seckel Syndrome Autosomal recessive pattern Additional reading about Seckel Syndrome National[littlepeopleuk.org]

  • Genee-Wiedemann Syndrome

    He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] Miller An extremely rare genetic mental retardation-multiple congenital anomalies syndrome.[whonamedit.com] They typically have normal intelligence and normal lifespans.[chop.edu]

  • Familial Congenital Nasolacrimal Duct Obstruction

    space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] […] retinopathy and mental retardation; {268050}), which has been mapped to chromosome 8q21.3-q22.1.[mendelian.co] […] is often subnormal and, in one study of 15 patients with Apert syndrome, the average IQ was 72.5. 66 Development may be adversely affected by progression of increased intracranial[entokey.com]

  • MORM Syndrome

    Based on the experience of mental retardation as it presents in that population, these individuals had mild to moderate mental retardation.[nature.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The average intelligence quotient (IQ) of adult males with the most severe mutation is 40, although those with less severe mutations can have IQs in the borderline to normal[spectrumnews.org]

  • Mild Dysmorphic Features

    , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com] Knight Karger Medical and Scientific Publishers , 15.02.2010 - 178 Seiten This remarkable publication focuses on the importance of genetics in mental retardation, investigating[books.google.de] Some individuals with this microduplication are “normal”- that is, they have average intelligence, no major birth defects, and no major medical illnesses.[c22c.org]

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