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1,823 Possible Causes for Average Intelligence, Neonatal Hypotonia, Wide Space Between the First and Second Toe

  • Down Syndrome

    Frequently the first feature noticed is hypotonia. Neonatal features of Down's syndrome General: Hyperflexibility. Muscular hypotonia.[patient.info] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] The intelligence quotient (IQ) among children with Down syndrome varies but averages about 50, compared with normal children, whose average IQ is 100.[merckmanuals.com]

  • Spinal Muscular Atrophy

    […] birth in the neonates.[ncbi.nlm.nih.gov] The brain is not affected, and they have been tested to have at least average to above average intelligence.[smasupport.com] It was hypothesised that their intelligence is comparable to controls, but not above average as previously postulated.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Spinal Muscular Atrophy Type 1

    The brain is not affected, and they have been tested to have at least average to above average intelligence.[smasupport.com]

    Missing: Wide Space Between the First and Second Toe
  • Russell-Silver Syndrome

    hypotonia Generalized low muscle tone in neonate 0008935 Hyperhidrosis Excessive sweating Increased sweating Profuse sweating Sweating Sweating profusely Sweating, increased[rarediseases.info.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Abnormal vagina morphology 0000142 Abnormality of the cardiovascular system Cardiovascular abnormality 0001626 Autistic behavior 0000729 Cafe-au-lait spot 0000957 Generalized neonatal[rarediseases.info.nih.gov]

  • Craniofrontonasal Dysplasia

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] In conclusion, individuals diagnosed with frontonasal dysplasia usually are of average intelligence and can expect a normal life span.[ruralneuropractice.com] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

    Missing: Neonatal Hypotonia
  • Rolandic Epilepsy

    良性先天性筋緊張低下症 benign familial hematuria 良性家族性血尿 benign familial neonatal convulsion/benign neonatal convulsion/familial benign neonatal convulsion 良性家族性新生児けいれん benign focal[jpeds.or.jp] Tiziana Zilli, Sergio Zanini, Stefania Conte, Renato Borgatti and Cosimo Urgesi, Neuropsychological assessment of children with epilepsy and average intelligence using NEPSY[doi.org] RESULT: the obtained data indicate that although intellectual efficiency (measured through the Intelligence Quatient - IQ) was within average, children with rolandic epilepsy[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Ring Chromosome 10

    hypotonia, normal to accelerated growth, autistic behaviour and minor dysmorphic features.[tp.amegroups.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] M–––FD, dysplastic featuresGeneralized hypotonia, PMDDBilateral Wilms tumorThe patient was a mosaic of three cell clones: 46,XY,r(11)(p15.5q25)/45,XY-11/47,XY,r(11)(p15.5q25[edmcasereports.com]

  • Nemaline Myopathy Type 5

    Clinical description It has a neonatal onset and patients present with hypotonia associated to contractures , a severe pectus carinatum, and tremor that subsides after 2-3[rarediseases.info.nih.gov] Two patients, however, had congenital mild hypotonia and weakness during the neonatal period.[synapse.koreamed.org] In a review of 14 patients and 85 cases from the literature, Martinez and Lake17 identified neonatal hypotonia as the most important prognostic sign in NM.[zdoc.site]

    Missing: Wide Space Between the First and Second Toe
  • Motor Neuron Disease

    SMA1 must be distinguished from other causes of neonatal hypotonia which include CNS malformations, metabolic diseases, infections, and congenital myopathies.[neuropathology-web.org]

    Missing: Wide Space Between the First and Second Toe
  • Prader-Willi Syndrome

    Hyperphagia, intellectual disabilities/behavioral disorders, neonatal hypotonia, and hypogonadism are cardinal features for PWS.[ncbi.nlm.nih.gov] […] and Fryns' study. [14] However, both studies suggest that most individuals (50–65%) fall within the mild/borderline/low average intelligence range.[en.wikipedia.org] The patient showed neonatal hypotonia, hyperphagia, obesity, central hypogonadism, hypothyroidism, strabismus.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe

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