Axonal Polyneuropathy: Causes & Reasons

Possible Causes for Axonal Polyneuropathy

What is chronic idiopathic axonal polyneuropathy? [patientslikeme.com]

Term A was “axonal”, “cryptogenic”, “idiopathic” or “unknown” and Term B was “neuropathy” or “polyneuropathy”. [link.springer.com]

Chronic idiopathic axonal polyneuropathy is an insidiously progressive sensory or sensorimotor polyneuropathy (a neurological disorder that occurs when many peripheral nerves [patientslikeme.com]

Arsenic-Induced Polyneuropathy

Because pathophysiology and symptoms are related, polyneuropathies are often classified by area of dysfunction: Myelin Vasa nervorum Axon Polyneuropathies may be acquired [merckmanuals.com]

Axonal degenerative polyneuropathies are usually symmetrical, and as the disorder progresses, the axons typically degenerate in a distal-to-proximal gradient. [clevelandclinicmeded.com]

[…] sensorimotor polyneuropathy Lymphomatous axonal sensorimotor polyneuropathy Infectious diseases Acquired immunodeficiency syndrome Lyme disease Sarcoidosis Toxic neuropathy [aafp.org]

Toxic Polyneuropathy

Because pathophysiology and symptoms are related, polyneuropathies are often classified by area of dysfunction: Myelin Vasa nervorum Axon Polyneuropathies may be acquired [merckmanuals.com]

Axonal degenerative polyneuropathies are usually symmetrical, and as the disorder progresses, the axons typically degenerate in a distal-to-proximal gradient. [clevelandclinicmeded.com]

Axonal Neuropathy / Polyneuropathy Sensory Neuropathy / Polyneuropathy Multifocal Motor Neuropathy (MMN) Multifocal Demyelinating Sensorimotor Neuropathy (Lewis Summer Syndromes [neuropathysupportnetwork.org]

Peripheral Motor Neuropathy

Axonal degenerative polyneuropathies are usually symmetrical, and as the disorder progresses, the axons typically degenerate in a distal-to-proximal gradient. [clevelandclinicmeded.com]

A distal dose-dependent axonal sensorimotor polyneuropathy has been described after treatment with vinorelbine. [pedsoncologyeducation.com]

Familial Progressive Polyneuropathy

The aims of this work are to report the possibility of a motor onset of amyloid polyneuropathy and to suggest the search for TTR mutations in familial cases of axonal polyneuropathy [ncbi.nlm.nih.gov]

A neurophysiological study delivered the diagnosis of axonal sensorimotor polyneuropathy. He later developed cardiac symptoms and diarrhea. [ruralneuropractice.com]

In contrast to the underlying causes of renal failure, which are often resulting in focal or demyelinating polyneuropathy, uremic polyneuropathy is axonal in nature. [neuroweb.us]

Paraneoplastic Polyneuropathy

Axonal degenerative polyneuropathies are usually symmetrical, and as the disorder progresses, the axons typically degenerate in a distal-to-proximal gradient. [clevelandclinicmeded.com]

Neurophysiologic investigations were indicative of a polyneuropathy with predominant axonic involvement in all 3 cases. [ncbi.nlm.nih.gov]

Sensorimotor dominant paraneoplastic polyneuropathy is characterized by degeneration of the dorsal column of the spinal cord and axonal degeneration (Rowland, 1995). [ispub.com]

Distal Spinal Muscular Atrophy Type 5

X-l) 1st–2nd decade (birth-adult) Chronic motor-sensory polyneuropathy De-remyelinating or axonal or intermediate DNA: >30 genes known Rehabilitation ± othosis ± foot surgery [neupsykey.com]

Axonal polyneuropathy was diagnosed at that time, and pneumonia with respiratory failure was cured with treatment. [journals.plos.org]

Electrophysiologically, CMTX1 shows mixed features of a demyelinating and axonal polyneuropathy [ 1 ]. [karger.com]

Serum Neuropathy

No specific treatment is available for chronic idiopathic axonal polyneuropathy. Painful neuropathy is difficult to treat. [patient.info]

Axonal degenerative polyneuropathies are usually symmetrical, and as the disorder progresses, the axons typically degenerate in a distal-to-proximal gradient. [clevelandclinicmeded.com]

Acute immune-mediated neuropathies include the Guillain-Barre syndrome (GBS; acute inflammatory demyelinating polyneuropathy), acute motor axonal polyneuropathy, acute sensory [questdiagnostics.com]

Alcoholic Neuropathy

Background Chronic axonal polyneuropathy is a well-known clinical sequela of excessive alcohol consumption; however, acute axonal polyneuropathy related to alcohol abuse is [jamanetwork.com]

Nerve conduction studies and needle electromyography disclose findings consistent with a generalized, sensorimotor, axonal degenerative, polyneuropathy. [ncbi.nlm.nih.gov]

[…] al·co·hol·ic pol·y·neu·rop·a·thy a nutritional axon loss polyneuropathy associated with chronic alcoholism. alcoholic neuropathy A nutritional neuropathy secondary to chronic [medical-dictionary.thefreedictionary.com]

Guillain-Barré Syndrome

Clinical presentation and neurophysiology were consistent with a severe axonal polyneuropathy. [ncbi.nlm.nih.gov]

An axonal form of Guillain-Barré syndrome was diagnosed, based on electrophysiological evidence of a generalized, non-length-dependent, sensorimotor axonal polyneuropathy. [ncbi.nlm.nih.gov]

Also, the NCS showed very mild changes, thus supporting a possible diagnosis of a mild distal motor axonal polyneuropathy. [jitc.biomedcentral.com]

Acute Pandysautonomia

The serial electrophysiologic studies revealed progressive periphear axonal polyneuropathy. [jkna.org]

Three main groups of axonal neuropathies may be present in haematological disorders: sensory neuronopathies, length-dependent polyneuropathies, and axonal polyneuropathy associated [mjhid.org]

Axonal sensory-motor polyneuropathy is a rare manifestation of a paraneoplastic syndrome and the association with lymphoma has been described in isolated cases.[ 34 ] Axonal [mjhid.org]

Non-Neuropathic Heredofamilial Amyloidosis

Sensory-motor axonal polyneuropathy and carpal tunnel syndrome are the most common types of neuropathy associated with AL amyloidosis. [dovepress.com]

Electrodiagnostic studies showed a severe axonal sensorimotor polyneuropathy with ongoing denervation changes (fibrillation potentials) seen on needle examination of distal [ng.neurology.org]

Later, he experienced paresthesia in the hands and impotence, and clinical and neurophysiological signs of axonal polyneuropathy and mixed parasympathetic and sympathetic [content.iospress.com]

Peripheral Sensory Neuropathy

The speed of progression of the polyneuropathy coupled with its nature (axonal or demyelinating) can help identify its aetiology. [rcemlearning.co.uk]

Axonal degenerative polyneuropathies are usually symmetrical, and as the disorder progresses, the axons typically degenerate in a distal-to-proximal gradient. [clevelandclinicmeded.com]

Diabetes and heavy alcohol use commonly cause symmetrical axonal polyneuropathies. [gmjournal.co.uk]

CANOMAD Syndrome

It is useful to classify polyneuropathies into two general categories based on pathophysiology: axonal and demyelinating. [medilib.ir]

In contrast to the underlying causes of renal failure, which are often resulting in focal or demyelinating polyneuropathy, uremic polyneuropathy is axonal in nature. [neuroweb.us]

Ganglioside GD1b is the target antigen for a biclonal IgM in a case of sensory-motor axonal polyneuropathy - involvement of N-Acetylneuraminic acid in the epitope. [medlink.com]

Peripheral Neuropathy

Initial nerve conduction studies (NCS) revealed motor axonal polyneuropathy with active denervation. [ncbi.nlm.nih.gov]

Four types of neuropathies were found: (i) predominantly axonal motor and sensory polyneuropathy, (ii) motor polyneuropathy, (iii) predominantly demyelinating motor and sensory [ncbi.nlm.nih.gov]

CONCLUSIONS: A severe axonal sensorimotor polyneuropathy developed in the intensive care unit following severe hypothermia. [ncbi.nlm.nih.gov]

Diphtheritic Neuropathy

Patients with AIDS may develop a chronic symmetric sensorimotor axonal polyneuropathy associated usually with no abnormal cerebrospinal fluid findings. [advances-in-medicine.net]

Remyelinating axons have thin myelin sheath. [orion-group.net]

Axonal degeneration of long nerve fibers is usually the underlying cause of polyneuropathies. [search.credoreference.com]

Spinocerebellar Ataxia with Axonal Neuropathy

polyneuropathy Neuronal loss in the Purkinje cell layer of the cerebellar vermis Neuronal loss in the dentate nuclei Neuronal loss in the inferior olives Thinning of the [datagenno.com]

In contrast to the underlying causes of renal failure, which are often resulting in focal or demyelinating polyneuropathy, uremic polyneuropathy is axonal in nature. [neuroweb.us]

Clinical features Ataxia, chorea, and axonal polyneuropathy Cutaneous photosensitivity and multiple cancers Mental and motor retardation Microcephaly Sensorineural deafness [emedicine.medscape.com]

Uremic Neuropathy

Electrophysiologic findings were consistent with a primarily axonal sensorimotor polyneuropathy. [ncbi.nlm.nih.gov]

These methods can also distinguish between axonal degeneration and demyelination, and characterize the disease as polyneuropathy or mononeuropathy. [symptoma.com]

Nerve conduction studies were performed, results of which were compatible with a severe, length-dependent, combined demyelinating and axonal, sensorimotor polyneuropathy. [bmcnephrol.biomedcentral.com]

Mononeuritis Multiplex

polyneuropathy. [casemed.case.edu]

Nerve conduction revealed a mixed motor and sensory axonal polyneuropathy with slowing of conduction velocities. [shmabstracts.com]

MONONEURITIS MULTIPLEX The pattern of a mononeuropathy multiplex is one of the most important patterns to recognize and differentiate from the length-dependent, dying-back, axonal [casemed.case.edu]

Chronic Inflammatory Demyelinating Polyneuropathy

A subset of CIDP involves predominantly distal parts of the limbs, which is similar to axonal polyneuropathy. [kci.go.kr]

Rather than clear demyelination, misdiagnosed patients most often had length-dependent axonal polyneuropathy, focal or multifocal demyelination that was limited to compressible [news-medical.net]

Ataxia-Oculomotor Apraxia Syndrome

Sensorimotor axonal polyneuropathy may appear and be confirmed by EMG. [bredagenetics.com]

All four patients showed elevated alpha-fetoprotein levels as well as moderately severe axonal sensory polyneuropathy with absent sensory nerve action potentials in the lower [cags.org.ae]

OMIM: 58 Head And Neck Eyes: nystagmus oculomotor apraxia slow saccades impaired ocular movements head-eye lag Neurologic Peripheral Nervous System: areflexia hyporeflexia axonal [malacards.org]

Mononeuritis

polyneuropathy. [casemed.case.edu]

Late occurrence of chronic immune-mediated axonal polyneuropathy following bone marrow transplant for juvenile-onset alpha-mannosidosis. [htct.com.br]

The speed of progression of the polyneuropathy coupled with its nature (axonal or demyelinating) can help identify its aetiology. [rcemlearning.co.uk]

Miller-Fisher Syndrome

Controversy exists concerning whether Miller Fisher syndrome (MFS) is the result of a predominantly axonal or demyelinating polyneuropathy and whether the Guillain-Barré syndrome [einstein.pure.elsevier.com]

Last electromyography showed a slightly prolonged ulnar F wave and persistence of the axonal sensory polyneuropathy. [frontiersin.org]

[…] action potential GM1a/b, GD1a & GalNac-GD1a Acute motor and sensory axonal neuropathy (AMSAN) Severe muscle weakness similar to AMAN but with sensory loss - Axonal polyneuropathy [en.wikipedia.org]

Charcot-Marie-Tooth Disease Type 2S

Alcoholic neuropathy is mainly the consequence of nutritional deficiency, particularly of thiamine and other B vitamins.It is predominantly a sensory motor axonal polyneuropathy [explainmedicine.com]

[…] number of phenocopies with axonal polyneuropathy of different genesis. [bmcmedgenet.biomedcentral.com]

Electroneuromyography: severe axonal sensory-motor polyneuropathy. [ijcasereportsandimages.com]

Diabetic Polyneuropathy

In medical practice, explanations other than IG should be sought for patients with atypical DPN (chronic idiopathic axonal polyneuropathy) who have IG. [ncbi.nlm.nih.gov]

Our observations are consistent with a progressive centripetal degeneration of axons in predominantly sensory diabetic polyneuropathy. [ncbi.nlm.nih.gov]

Hyperexcitability in diabetic polyneuropathy may, at least in part, be caused by dysfunctional axonal hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. [ncbi.nlm.nih.gov]

Axonal Neuropathy

Background: Chronic idiopathic axonal polyneuropathy (CIAP) is an insidiously progressive sensory or sensorimotor polyneuropathy that affects elderly people. [cochrane.org]

Acute axonal polyneuropathy following resection of a glioblastoma multiforme. [neurologyindia.com]

Electrophysiologic studies invariably show axonal polyneuropathy. [jamanetwork.com]

Charcot-Marie-Tooth Disease Type 4B3

Sensorimotor axonal polyneuropathy was found with nerve conduction velocities between 34 and 46 m/s. [cags.org.ae]

Chronic sensorimotor axonal polyneuropathy is the predominant pattern, whereas demyelinating patterns are less common [11,12,13]. [bmcmedgenomics.biomedcentral.com]

Nerve biopsy of the oldest brother found moderately depleted myelinated axons of all fibre size, no onion bulbs and some axonal sprouting. [cags.org.ae]

Charcot-Marie-Tooth Disease Type 2B2

Disease definition Charcot-Marie-Tooth disease, type 2B2 (CMT2B2, also referred to as CMT4C3) is an axonal CMT peripheral sensorimotor polyneuropathy that has been described [orpha.net]

An axonal Charcot-Marie-Tooth peripheral sensorimotor polyneuropathy that has been described in a large consanguineous Costa Rican family of Spanish ancestry. [ncbi.nlm.nih.gov]

Autoimmune Autonomic Ganglionopathy

These unique features set these disorders apart from the more common length-dependent axonal sensory polyneuropathies. [practicalneurology.com]

Amyloidosis may also present in the form of dysautonomia associated with peripheral axonal polyneuropathy.5 However, our patient did not present heart, kidney, or peripheral [elsevier.es]

Individuals may develop chronic painful nonlength-dependent sensory neuronopathy or a length-dependent axonal sensory polyneuropathy. [practicalneurology.com]

GALOP Syndrome

PMID: 33334756 Immune Axonal Polyneuropathy. Tavee JO. Tavee JO. [pubmed.ncbi.nlm.nih.gov]

Electrophysiologic examination showed abnormalities supporting a diagnosis of sensory motor polyneuropathy with primary axonal loss. [go.gale.com]

Provides independent support for a diagnosis of an immune-mediated sensory-motor or sensory polyneuropathy. The neuropathy may be either demyelinating or axonal. [neuromuscular.wustl.edu]