Babinski Sign: Causes & Reasons

Possible Causes for Babinski Sign

Autosomal Dominant Spastic Paraplegia Type 29

Related phenotypes are lower limb hyperreflexia and babinski sign [malacards.org]

Affiliated tissues include spinal cord and skeletal muscle, and related phenotypes are babinski sign and degeneration of the lateral corticospinal tracts Disease Ontology [malacards.org]

Affiliated tissues include spinal cord, skeletal muscle and skin, and related phenotypes are babinski sign and degeneration of the lateral corticospinal tracts Disease Ontology [malacards.org]

Autosomal Dominant Spastic Paraplegia Type 6

Related phenotypes are babinski sign and talipes equinovarus Disease Ontology : 12 A hereditary spastic paraplegia that has material basis in mutation in the ZFYVE27 gene [malacards.org]

Showing of 26 | 80%-99% of people have these symptoms Babinski sign 0003487 Gait disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Impaired vibratory [rarediseases.info.nih.gov]

Autosomal Dominant Spastic Paraplegia Type 9A

Hoffmann's sign and Babinski's sign also can be seen. [explainmedicine.com]

Figure 6.2 Babinski sign. Babinski sign. A classic neurological test for corticospinal tract damage is the Babinski test. [nba.uth.tmc.edu]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Autosomal Dominant Spastic Paraplegia Type 42

Affiliated tissues include spinal cord and skeletal muscle, and related phenotypes are babinski sign and degeneration of the lateral corticospinal tracts Disease Ontology [malacards.org]

Affiliated tissues include spinal cord, skeletal muscle and skin, and related phenotypes are babinski sign and degeneration of the lateral corticospinal tracts Disease Ontology [malacards.org]

The pure form presents isolated pyramidal signs such as spasticity, hyperreflexia, Babinski sign, and motor deficits, which can be associated with sphincter disorder and deep [neurohic.com]

Autosomal Dominant Spastic Paraplegia Type 31

sign 0003487 Lower limb muscle weakness Lower extremity weakness Lower limb weakness Muscle weakness in lower limbs [ more ] 0007340 Skeletal muscle atrophy Muscle degeneration [rarediseases.info.nih.gov]

0000012 Percent of people who have these symptoms is not available through HPO Ankle clonus Abnormal rhythmic movements of ankle 0011448 Autosomal dominant inheritance 0000006 Babinski [rarediseases.info.nih.gov]

Autosomal Dominant Spastic Paraplegia Type 10

sign 0003487 Distal sensory impairment Decreased sensation in extremities 0002936 Hyperreflexia in upper limbs 0007350 Impaired distal vibration sensation 0006886 Leg muscle [rarediseases.info.nih.gov]

99% of people have these symptoms Distal lower limb amyotrophy 0008944 Lower limb hyperreflexia Overactive lower leg reflex 0002395 30%-79% of people have these symptoms Babinski [rarediseases.info.nih.gov]

Behr Syndrome

sign, and incoordination. [whonamedit.com]

Unusual foot reflexes (a positive Babinski sign) may also be experienced by the patient when the sole is stimulated. [medigest.uk]

sign). [the-medical-dictionary.com]

Autosomal Recessive Spastic Paraplegia Type 18

The pyramidal syndrome is characterised by brisk patellar tendon reflexes and the Babinski sign. [orpha.net]

Showing of 42 | 30%-79% of people have these symptoms Abnormality of jaw muscles 0045037 Ankle contracture 0006466 Babinski sign 0003487 Cough Coughing 0012735 Delayed gross [rarediseases.info.nih.gov]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Autosomal Dominant Spastic Paraplegia Type 4

Neurological examination disclosed mild spasticity and weakness in the legs, hyperreflexia in all limbs, and bilateral Babinski sign. [bmcmedgenet.biomedcentral.com]

sign 0003487 Distal sensory impairment Decreased sensation in extremities 0002936 Hyperreflexia Increased reflexes 0001347 Impaired vibration sensation in the lower limbs [rarediseases.info.nih.gov]

Showing of 39 | 30%-79% of people have these symptoms Ankle clonus Abnormal rhythmic movements of ankle 0011448 Babinski sign 0003487 Brisk reflexes 0001348 Functional motor [rarediseases.info.nih.gov]

Amyotrophic Lateral Sclerosis Type 4

Typical symptoms include distal muscle weakness and atrophy, brisk deep-tendon reflexes and a positive Babinski sign (Chen et al. Am J Hum Genet 74:1128-1135, 2004). [preventiongenetics.com]

There are no standard laboratory tests for upper motor neuron disease, but spasticity (a specific type of stiffness), abnormally brisk tendon reflexes, Babinski’s sign and [memory.ucsf.edu]

During neurological examination, pyramidal signs can be observed. ALS4 patients show hyperreflexia, have brisk deep-tendon reflexes and the Babinski sign is present. [symptoma.com]

Autosomal Recessive Spastic Paraplegia Type 32

sign 32 HP:0003487 10 lower limb muscle weakness 32 HP:0007340 11 ankle clonus 32 HP:0011448 Drugs & Therapeutics for Spastic Paraplegia 32, Autosomal Recessive Genetic Tests [malacards.org]

sign 60 33 Frequent (79-30%) HP:0003487 3 pes cavus 60 33 Obligate (100%) HP:0001761 4 difficulty walking 60 33 Obligate (100%) HP:0002355 5 hypoplasia of the corpus callosum [malacards.org]

The deep tendon reflexes were increased in all four limbs, but Babinski sign was not elicited bilaterally. Neither ankle nor knee clonus was observed. [nature.com]

Autosomal Recessive Spastic Paraplegia Type 56

Affiliated tissues include globus pallidus, and related phenotypes are lower limb hyperreflexia and babinski sign Disease Ontology : 12 A hereditary spastic paraplegia that [malacards.org]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Babinski sign was negative. Video gait analysis was performed, which showed internal rotation of the hips and feet while walking and running. [omicsonline.org]

Autosomal Dominant Spastic Paraplegia Type 37

SPASTIC PARAPLEGIA 19, AUTOSOMAL DOMINANT; SPG19 Is also known as ;spg19 Related symptoms: Autosomal dominant inheritance Spasticity Hyperreflexia Babinski sign Slow progression [mendelian.co]

Affiliated tissues include globus pallidus, skin and bone, and related phenotypes are babinski sign and lower limb hyperreflexia Disease Ontology : 12 A hereditary spastic [malacards.org]

sign 0003487 Cerebellar atrophy Degeneration of cerebellum 0001272 Impaired vibration sensation in the lower limbs Decreased lower limb vibratory sense Decreased vibratory [rarediseases.info.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 7

The deep tendon reflexes were increased in all four limbs, but Babinski sign was not elicited bilaterally. Neither ankle nor knee clonus was observed. [nature.com]

Other common symptoms of HSP are urinary urgency and frequency, hyperactive reflexes, difficulty with balance, clonus, Babinski’s sign, diminished vibration sense in the feet [sp-foundationorg.presencehost.net]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 27

sign 59 32 hallmark (90%) Very frequent (99-80%) HP:0003487 4 dysdiadochokinesis 59 32 occasional (7.5%) Occasional (29-5%) HP:0002075 5 spastic paraplegia 59 32 hallmark [malacards.org]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

HPO Source Accession 1 dysarthria 59 32 occasional (7.5%) Occasional (29-5%) HP:0001260 2 sensorineural hearing impairment 59 32 very rare (1%) Very rare ( HP:0000407 3 babinski [malacards.org]

X-Linked Spastic Paraplegia Type 34

Hoffmann's sign and Babinski's sign also can be seen. [explainmedicine.com]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

sign + + Vibration sense Normal Normal Sphincter involvement − − Mini-Mental State Examination (MMSE) 16/30 25/30 Lower limb NCV FWCV decreased Decreased Sural nerve biopsy [intechopen.com]

Juvenile Primary Lateral Sclerosis

Hyperreflexia is another key feature of PLS as seen in patients presenting with the Babinski's sign. [en.wikipedia.org]

sign 0003487 Cerebral cortical atrophy Decrease in size of the outer layer of the brain due to loss of brain cells 0002120 Childhood onset Symptoms begin in childhood 0011463 [rarediseases.info.nih.gov]

´s sign present) Diagnosis [ ✎ edit | edit source ] There is no specific test for primary lateral sclerosis. [wikilectures.eu]

Autosomal Dominant Spastic Paraplegia Type 17

Affiliated tissues include globus pallidus, skin and bone, and related phenotypes are babinski sign and lower limb hyperreflexia Disease Ontology : 12 A hereditary spastic [malacards.org]

Showing of 25 | 30%-79% of people have these symptoms Babinski sign 0003487 Foot dorsiflexor weakness Foot drop 0009027 Hand muscle atrophy Hand muscle degeneration 0009130 [rarediseases.info.nih.gov]

Pallidopyramidal Syndrome

sign 0003487 Bradykinesia Slow movements Slowness of movements [ more ] 0002067 Dysphagia Poor swallowing Swallowing difficulties Swallowing difficulty [ more ] 0002015 Dystonia [rarediseases.info.nih.gov]

Names Learn More: HPO ID 100% of people have these symptoms Parkinsonism 0001300 30%-79% of people have these symptoms Abnormal autonomic nervous system physiology 0012332 Babinski [rarediseases.info.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 46

Showing of 36 | 80%-99% of people have these symptoms Babinski sign 0003487 Impaired vibratory sensation Decreased vibration sense Decreased vibratory sense Diminished vibratory [rarediseases.info.nih.gov]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Detailed neurological examination showed predominantly bilateral proximal pronounced paresis (3/4) of the lower limbs with hyperreflexia and positive bilateral Babinski sign [omicsonline.org]

Autosomal Recessive Spastic Paraplegia Type 39

Neurological examination disclosed mild spasticity and weakness in the legs, hyperreflexia in all limbs, and bilateral Babinski sign. [bmcmedgenet.biomedcentral.com]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Detailed neurological examination showed predominantly bilateral proximal pronounced paresis (3/4) of the lower limbs with hyperreflexia and positive bilateral Babinski sign [omicsonline.org]

Autosomal Dominant Spastic Paraplegia Type 13

sign 60 33 occasional (7.5%) Frequent (79-30%) HP:0003487 4 lower limb muscle weakness 60 33 frequent (33%) Frequent (79-30%) HP:0007340 5 impaired vibration sensation in [malacards.org]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 14

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

sign 34 Clinical presentation Symptoms typically begin sometime between the ages of 5 to 15 years, scoliosis Diabetes (about 20% of people with Friedreich's ataxia develop [slideplayer.com]

Detailed neurological examination showed predominantly bilateral proximal pronounced paresis (3/4) of the lower limbs with hyperreflexia and positive bilateral Babinski sign [omicsonline.org]

Autosomal Dominant Spastic Paraplegia Type 19

Related phenotypes are babinski sign and talipes equinovarus Disease Ontology : 12 A hereditary spastic paraplegia that has material basis in mutation in the ZFYVE27 gene [malacards.org]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Deep tendon reflexes were increased in all patients with clonus in 3 and bilateral Babinski sign in 4. [bmcneurol.biomedcentral.com]

Autosomal Recessive Spastic Paraplegia Type 26

Showing of 37 | 30%-79% of people have these symptoms Babinski sign 0003487 Cerebral cortical atrophy Decrease in size of the outer layer of the brain due to loss of brain [rarediseases.info.nih.gov]

Achilles and brachioradialis reflexes were absent, but Babinski sign was present. Distal muscles in the lower limbs were atrophic, and gait was spastic ataxic. [docplayer.net]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 55

The deep tendon reflexes were increased in all four limbs, but Babinski sign was not elicited bilaterally. Neither ankle nor knee clonus was observed. [nature.com]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

sign + + Vibration sense Normal Normal Sphincter involvement − − Mini-Mental State Examination (MMSE) 16/30 25/30 Lower limb NCV FWCV decreased Decreased Sural nerve biopsy [intechopen.com]

Autosomal Dominant Spastic Paraplegia Type 8

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

Babinski sign was negative. Video gait analysis was performed, which showed internal rotation of the hips and feet while walking and running. [omicsonline.org]

Autosomal Recessive Spastic Paraplegia Type 21

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

’s sign). [medschool.lsuhsc.edu]

Detailed neurological examination showed predominantly bilateral proximal pronounced paresis (3/4) of the lower limbs with hyperreflexia and positive bilateral Babinski sign [omicsonline.org]

Autosomal Recessive Spastic Paraplegia Type 57

Reflexes were brisk, and he showed ankle clonus and a Babinski sign on the left. [ng.neurology.org]

There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign. [journals.plos.org]

sign, and scoliosis; within 10 to 15 years of onset, patients have to use wheelchairs. 22 In addition to axonal sensory polyneuropathy, auditory and optic neuropathy are [elsevier.es]

Aromatic L-Amino Acid Decarboxylase Deficiency

The typical symptoms of the syndrome are: Muscular hypotonia of the trunk, Myoclonus, Miosis, Irritability, Limb dystonia, Limb hypertonia, Babinski sign, Choreoathetosis, [fdna.health]

The signs and symptoms of Aromatic L-Amino Acid Decarboxylase Deficiency Disorder may include: Babinski sign Choreoathetosis Constipation Decreased CSF homovanillic acid Diarrhea [dovemed.com]

sign 0003487 Choreoathetosis 0001266 Constipation 0002019 Decreased CSF homovanillic acid 0003785 Diarrhea Watery stool 0002014 Emotional lability Emotional instability 0000712 [rarediseases.info.nih.gov]