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690 Possible Causes for Back Pain, Dark Urine, Personality Change

  • Malignant Neoplasm of Pancreas

    Psychosocial Assess for the presence of irritability, depression, and personality changes.[medical-dictionary.thefreedictionary.com] Unexplained weight loss, abdominal pain, nausea, vomiting. Back pain is another one, because the pancreas is very posterior in the body.[scientificamerican.com] […] either diarrhoea or severe constipation jaundice (yellowish skin and eyes, and dark urine).[cancer.org.au]

  • Porphyria

    Symptoms include pain in the chest, abdomen, limbs, or back; muscle numbness, tingling, paralysis, or cramping; vomiting; constipation; and personality changes or mental disorders[medlineplus.gov] The imbalance can contribute to some of these symptoms: Abdominal pain , often severe Chest pain Increased heart rate and blood pressure Limb and back pain Muscle weakness[webmd.com] Signs and Symptoms Diagnosis Treatment Symptoms vary depending on the type of porphyria, but some of the more common include: Dark urine Skin sensitivity, including blistering[ucsfhealth.org]

  • Acute Hepatic Porphyria

    Acute hepatic porphyria can be triggered by pregnancy and usually presents with gastrointestinal symptoms and personality changes.[ncbi.nlm.nih.gov] Symptoms may include vomiting, abdominal or back pain, weakness in arms or legs, and mental symptoms. Laboratory tests are done on urine samples taken during the attack.[merckmanuals.com] Muscle weakness, tremor, diaphoresis, dysuria, dark urine, bladder distension and severe neuropathy may be encountered as well, and a missed diagnosis may lead to severe and[symptoma.com]

  • Acute Intermittent Porphyria

    During an attack, symptoms can include muscle numbness, tingling, paralysis, cramping, and personality or mental changes.[icd9data.com] Back pain (10/32) was the most frequent AIP pain symptom and sweet craving (10/15) was the most frequent PMS symptom.[ncbi.nlm.nih.gov] urine.[ncbi.nlm.nih.gov]

  • Vitamin B12 Deficiency

    Particularly back pain, Peripheral Neuropathy and Symptoms of Fibromyalgia .[easy-immune-health.com] ., paresthesia, peripheral neuropathy, spinal cord degeneration), Psychiatric symptoms (irritability, personality change, depression), Cardiovascular problems (e.g., myocardial[kidsnewtocanada.ca] changes.[www2.gov.bc.ca]

  • Pancreatic Adenocarcinoma

    Abdominal pain and back pain were the presenting symptoms in 75% and 33.3% of patients respectively.[ncbi.nlm.nih.gov] Genetic factors Damage or changes in a person's DNA can lead to damage in the genes that control cell division. Hereditary genetic changes pass down through a family.[medicalnewstoday.com] […] either diarrhoea or severe constipation jaundice (yellowish skin and eyes, and dark urine).[cancer.org.au]

  • Paroxysmal Nocturnal Hemoglobinuria

    Some gene mutations are acquired during a person's lifetime and are present only in certain cells. These changes, which are called somatic mutations, are not inherited.[ghr.nlm.nih.gov] Abstract A 41-year-old woman with a Harrington spondylodesis presented with lower back pain.[ncbi.nlm.nih.gov] Two years after disease onset, while pancytopenia remained stable, occurrence of morning dark urine led to found a paroxysmal nocturnal hemoglobinuria clone.[ncbi.nlm.nih.gov]

  • Variegate Porphyria

    Those with acute forms of porphyria develop numbness, tingling, paralysis, cramping, vomiting, constipation, personality changes or mental disorders, and/or pain in the abdomen[medicinenet.com] Pain, Acute Bleeding, Gastrointestinal Breast Mass Dyspepsia Fatigue Hypernatremia Hypocalcemia Jaundice, Neonatal[books.google.com] The patient recalled passing dark urine after surgery and was subsequently hospitalized for 3 months.[medicaljournals.se]

  • Kidney Disease

    In many cases, the correct treatment and lifestyle changes can help keep a person and their kidneys healthier longer.[davita.com] […] of parts of the body, particularly eyes, ankles or wrists Burning or abnormal discharge during urination Changes in the frequency of urination, especially at night Lower back[umm.edu] Such diets can induce metabolic acidosis in individuals with reduced GFR, including otherwise healthy elderly persons ( 28 ).[doi.org]

  • Ochronosis with Alkaptonuria

    Ear wax of a person with ochronosis will also be dark in color.[aocd.org] pain & stiffness with deposition of pigment in the intervertebral discs & later calcification May resemble Anklosing Spondylitis but sacroiliac joints spared Then large joint[orthofracs.com] Dark urine (after exposure to sunlight). Images: Ochronosis - eye (nejm.org) . Ochronosis - hip (nih.gov/CMAJ) .[librepathology.org]

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