The major risk factors for esophageal adenocarcinoma include Barrett’s esophagus, gastroesophageal reflux, tobacco use and obesity [ 2 ].
Barrett esophagus and risk of esophageal cancer: a clinical review. JAMA, 310 (6), 627-636. Spechler, S. J., & Souza, R. F. (2014). Barrett's esophagus.
Introduction: Esophageal cancer can be adenocarcinoma (typically in the lower esophagus, arising from reflux and Barrett's esophagus) or squamous cell carcinoma (typically