Basal Ganglia Calcification: Causes & Reasons

Possible Causes for Basal Ganglia Calcification

Abstract A case of a complete Kearns-Sayre syndrome, of early onset, associated with cerebral and cerebellar leukodystrophy and basal ganglia calcification is reported. [link.springer.com]

CT CT scan of the brain shows basal ganglia siderocalcific deposits and subcortical calcifications (with or without basal ganglia deposits), and diffuse supratentorial and [radiopaedia.org]

All cases need not have basal ganglia calcification, and there may only be areas of T2 prolongation in these regions. [ajnr.org]

Pseudohypoparathyroidism

The brain computed tomography revealed the basal ganglia calcification of the patient, accompanying by serum hypocalcemia and hyperphosphatemia. [ncbi.nlm.nih.gov]

[…] exostoses: short metaphyseal or more central and perpendicular to long axis of a bone broad bones with coned epiphyses CNS / head and neck manifestations basal ganglia calcification [radiopaedia.org]

Hypoparathyroidism is one of the most common causes of pathological basal ganglia calcification. [jdrntruhs.org]

MELAS Syndrome

Characteristic radiological anomalies, such as bilateral basal ganglia calcification, focal hypodensities, and generalized atrophy, can be detected on cerebral imaging [ 4 [academic.oup.com]

calcifications. [ncbi.nlm.nih.gov]

Prominent bilateral basal ganglia calcifications and vascular sclerosis were present, and a small remote left temporal lobe infarct was seen. [ncbi.nlm.nih.gov]

Infantile Choroidocerebral Calcification Syndrome

Key words Physiological calcification Tumours Hamartoma Neuroectodermal Vascular Infective Basal ganglia calcification This is a preview of subscription content, log in to [link.springer.com]

UMLS MONDO ORPHANET More info about IMMUNODEFICIENCY 38 WITH BASAL GANGLIA CALCIFICATION; IMD38 Low match BASAL GANGLIA CALCIFICATION, IDIOPATHIC, 6; IBGC6 Idiopathic basal [mendelian.co]

Diffuse basal ganglia calcification (15%) bore little relation to the diverse clinical symptomatology, and routine biochemical studies showed a disorder of metabolism to be [ncbi.nlm.nih.gov]

Hypoparathyroidism

Investigate for hypoparathyroidism in the presence of basal ganglia calcification. 2. [bcmj.org]

[…] of the basal ganglia; however, the factors that predispose individuals to basal ganglia calcification have not been identified[11]. [nnjournal.net]

[…] in the basal ganglia. [ncbi.nlm.nih.gov]

Presenile Dementia with Bone Cysts

From Epidemiology ~160 cases, mainly in Finland & Japan onset third decade Pathology basal ganglia calcification gliosis white matter demyelination senile plaques neurofibrillary [anvita.info]

ganglia calcification, dementia, and bone cysts: DAP12 and TREM2. [ PMID 17125796 ] A novel compound heterozygous mutation in the DAP12 gene in a patient with Nasu-Hakola [snpedia.com]

(d) Non-contrast CT scan of the brain showing calcifications in bilateral basal ganglia. [neurologyindia.com]

Bonnemann-Meinecke-Reich Syndrome

Ganglia-Calcification ⌊ Pontoneocerebellar Hypoplasia ⌊ Encephalopathy Intracerebral Calcification Retinal ⌊ Cerebral Autosomal Dominant Arteriopathy ... ⌊ Cerebral Disorders [wellnessadvocate.com]

True periventricular calcification with spots or rocks is seen, as is basal ganglia and cortical calcification. [docksci.com]

Ganglia Calcification, Idiopathic, Childhood-Onset Bloom Syndrome Bonnemann-Meinecke-Reich Syndrome Branchio-Oculo-Facial Syndrome Branchiooculofacial Syndrome Campomelia [familydiagnosis.com]

Hirschsprung Disease Type D-Brachydactyly Syndrome

[…] syndrome SUFU Basal ganglia calcification type 1, ideopathic SLC20A2 Basal ganglia calcification type 4 PDGFRB Basal ganglia calcification type 5, idiopathic PDGFB Basal [centogene.com]

Ganglia Calcification, Idiopathic, 1 1 Basal Ganglia Calcification, Idiopathic, 4 2 Basal Ganglia Calcification, Idiopathic, 5 1 Basal Ganglia Calcification, Idiopathic, [preventiongenetics.com]

ganglia calcification type 6, idiopathic XPR1 Beta-ureidopropionase deficiency UPB1 Bifid nose FREM1 Birt-Hogg-Dube syndrome FLCN Bjornstad syndrome BCS1L Blau syndrome NOD2 [centogene.com]

Cockayne Syndrome

[…] infection: Periventricular and cortical malformations with thick calcifications in germinal matrix and periventricular regions and faint/punctate basal ganglia calcifications [ajnr.org]

ganglia calcification on CT occurred later. [ncbi.nlm.nih.gov]

Pelizaeus-Merzbacher disease: X-linked leukodystrophy without intracranial calcifications Aicardi-Goutieres syndrome: Punctate and small basal ganglia calcifications Cytomegalovirus [ajnr.org]

Juvenile Paralysis Agitans of Hunt

Ganglia Calcification, Idiopathic, 1 Basal Ganglia Calcification, Idiopathic, 5 Basal Ganglia Calcification, Idiopathic, 6 Basal Ganglia Calcification, Idiopathic, Childhood-Onset [familydiagnosis.com]

Includes: Calcification of basal ganglia G23.9 Degenerative disease of basal ganglia, unspecified [emprocell.com]

ganglia degeneration Basal ganglia degeneration with calcification Choreoacanthocytosis Disorder of basal ganglia Fahr's syndrome Juvenile paralysis agitans of Hunt Multiple [emedcodes.com]

Secondary Hypoparathyroidism

Investigate for hypoparathyroidism in the presence of basal ganglia calcification. 2. [bcmj.org]

Incidentally discovered basal ganglia calcifications should lead to endocrinologic evaluation of parathyroid function. [neurology.org]

Nine patients underwent a head computed tomography scan and five patients had evidence of basal ganglia calcification. [8] According to literature, basal ganglia calcification [ruralneuropractice.com]

Familial Isolated Hypoparathyroidism

Calcification of the basal ganglia: Computerized tomography and clinical correlation. Neurology 1979;29:328-33. [ PUBMED ] 5. [jnsbm.org]

More than one third of patients develop ectopic and basal ganglia calcifications. PTH concentrations are usually in the low-normal range. [iofbonehealth.org]

The serum magnesium (2.1 mg/ dl), CT scan (no basal ganglia calcification), audiometry, EEG, ECG and cardiac evaluation were all normal. [indianpediatrics.net]

Infantile Convulsions and Choreoathetosis

GANGLIA CALCIFICATION, IDIOPATHIC, 6; IBGC6 Idiopathic basal ganglia calcification is an autosomal dominant neurodegenerative disorder characterized by adult onset of progressive [mendelian.co]

ganglia calcification, chorea, and dystonia. ( 9087991 ) Klein C....KAPmpf D. 1997 10 Paroxysmal choreoathetosis--a disorder related to Huntington's disease? [malacards.org]

Computed tomography showed calcifications in the basal ganglia, thalamus, and cerebral white matter. He had a history of infantile convulsions with a benign outcome. [wwww.unboundmedicine.com]

Singleton Merten Syndrome

In 1984, Aicardi and Goutières defined a phenotype resembling congenital viral infection with basal ganglia calcification and increased protein content in the cerebrospinal [ncbi.nlm.nih.gov]

Here we present a male child demonstrating recurrent febrile episodes, spasticity and basal ganglia calcification suggestive of Aicardi-Goutières syndrome, who carries the [research.manchester.ac.uk]

In this study, we present a male child demonstrating recurrent febrile episodes, spasticity, and basal ganglia calcification suggestive of Aicardi–Goutières syndrome, who [liebertpub.com]

Oculodentodigital Dysplasia

Important differential diagnoses of basal ganglia calcification of familial nature are Fahr’s syndrome (familial idiopathic symmetrical basal ganglia calcification), Cockayne [sajr.org.za]

Keywords: Basal ganglia calcification, GJA1 gene, oculodentodigital dysplasia DOI: 10.3233/JAD-150424 Journal: Journal of Alzheimer's Disease, vol. 49, no. 1, pp. 27-30, 2016 [content.iospress.com]

CT of the head also revealed bilateral basal ganglia calcification. The patient did not have any features of mental retardation. [sajr.org.za]

Beta-Propeller Protein-Associated Neurodegeneration

Although the characteristic features of beta-propeller protein-associated neurodegeneration were present in our patient, the observation of basal ganglia calcification was [ncbi.nlm.nih.gov]

calcification from hemorrhagic foci.14 Thefinding of hypointensity of the basal ganglia on GRE or SWIis often taken to signify iron deposition. [documents.tips]

Basal ganglia calcification in a patient with beta-propeller protein-associated neurodegeneration. [thieme-connect.com]

Senile Chorea

calcification)Basal ganglia calcification on neuroimaging; linkage to chromosome 14q Hereditary Creutzfeldt-Jakob disease15% of Creutzfeldt-Jakob disease cases are dominant [clinchem.aaccjnls.org]

ganglia calcification in each of the three remaining cases. [ncbi.nlm.nih.gov]

Africa Benign hereditary choreaChildhood onset; other neurologic signs may exist; occasionally progressive; linkage to chromosome 14q Fahr disease (idiopathic basal ganglia [clinchem.aaccjnls.org]

Pseudohypoparathyroidism Type 2

[…] towards basal ganglia. [abstracts.eurospe.org]

Brain MRI scan: basal ganglia calcification (sign of a long-standing hypocalcaemic state). Genetic studies: as appropriate. [patient.info]

Cerebro-Oculo-Facio-Skeletal Syndrome Type 1

His brain imaging revealed extensive basal ganglia calcifications. He has normal ultraviolet sensitivity. [ncbi.nlm.nih.gov]

CT Cockayne syndrome is one of the causes of basal ganglia calcifications in a child. Calcification may also occur in cerebellar and cerebral cortical regions. [radiopaedia.org]

ganglia calcification Cerebellar ataxia Cerebellar atrophy Cerebral atrophy Decreased nerve conduction velocity Dementia Dysarthria Gait disturbance Global developmental [ncbi.nlm.nih.gov]

Mesoaxial Synostotic Syndactyly with Phalangeal Reduction

[…] with simplified gyration and polymicrogyria Baraitser-Winter syndrome Basal cell nevus syndrome Basal ganglia calcification Beta-ureidopropionase deficiency Bifid nose Birt-Hogg-Dube [qlinics.com]

ganglia calcification type 6, idiopathic XPR1 Beta-ureidopropionase deficiency UPB1 Bifid nose FREM1 Birt-Hogg-Dube syndrome FLCN Bjornstad syndrome BCS1L Blau syndrome NOD2 [centogene.com]

Acroosteolysis-Keloid-Like Lesions-Premature Aging Syndrome

Distinct mutations in PDGFRB have been shown to cause infantile myofibromatosis, idiopathic basal ganglia calcification, and an overgrowth disorder with dysmorphic facies [unboundmedicine.com]

ganglia calcification childhood-onset Olivopontocerebellar atrophy deafness Megalocornea-intellectual disability syndrome Chromosome 17p13.1 deletion syndrome Dandy-Walker [checkrare.com]

[…] telangiectasia type 3 Naguib-Richieri-Costa syndrome Primary hypomagnesemia with secondary hypocalcemia Oculomotor apraxia Cogan type Oligodactyly tetramelic postaxial Idiopathic basal [checkrare.com]

Spondyloenchondrodysplasia

Both the sibs had normal intelligence and no calcification of the basal ganglia. [ncbi.nlm.nih.gov]

Patients may exhibit varying degrees of neurological impairment including spasticity, developmental delay, and basal ganglia calcification. [genome.jp]

Patient may exhibit varying degrees of neurological impairment including spasticity, developmental delay and basal ganglia calcification [ 3 ]. [ped-rheum.biomedcentral.com]

Thickened Earlobes-Conductive Deafness Syndrome

[…] retinal Encephalopathy progressive optic atrophy Encephalopathy subacute spongiform, Gerstmann-Stra Encephalopathy-basal ganglia-calcification Encephalophathy recurrent of [bioreference.net]

Encephalopathy-basal ganglia-calcification[?] Encephalophathy recurrent of childhood[?] Encephalotrigeminal angiomatosis[?] Enchondromatosis (benign)[?] [encyclopedia.kids.net.au]

[…] lipomatosis Encephalocele anencephaly Encephalocele anterior Encephalocele frontal Encephalocele Encephalomyelitis, Myalgic Encephalomyelitis Encephalopathy intracerebral calcification [bioreference.net]

MERRF Syndrome

Oligosymptomatic relatives were variably affected by lipomas, goitre, brain atrophy, and basal ganglia calcifications. [ncbi.nlm.nih.gov]

Brain imaging techniques like magnetic resonance imaging are able to diagnose stroke, brainstem atrophy, cerebellar atrophy and basal ganglia calcification, while magnetic [symptoma.com]

Magnetic resonance imaging of the brain may show cortical atrophy, basal ganglia calcifications and leucodystrophy. [orpha.net]

Cerebro-Facio-Thoracic Dysplasia

Illum F (1980): Calcification of the basal ganglia following carbon monoxide poisoning. Neuroradiology 19:213-214. [documents.tips]

Aicardi-Goutieres syndrome (Encephalopathy-basal ganglia-calcification) Alcaptonuria. Homogentisic acid oxydase deficiency. [neurometplus.com]

Primary Hypomagnesemia with Secondary Hypocalcemia

The child was also found to have bilateral basal ganglia calcification, which improved with Mg therapy. [sjkdt.org]

Resolving basal ganglia calcification in hereditary hypomagnesemia with secondary hypocalcemia due to a novel TRPM6 gene mutation. [neurologyindia.com]

A computed tomography brain scan, done around the time of diagnosis, identified bilateral basal ganglia calcification (BGC). [sjkdt.org]

Amelogenesis Imperfecta Type 2A5

ganglia calcification,idiopathic,5, Meningioma, SIS-related,607174 23 PDGFRB % 97% Basal ganglia calcification idiopathic 4, Myeloproliferative disorder with eosinophilia [docplayer.net]

ganglia calcification High pitched voice Hypoparathyroidism Delayed cranial suture closure Hypocalcemia Increased bone mineral density Small nail High myopia Decreased testicular [mendelian.co]

[…] cell carcinoma somatic,605462 SMO Basal cell carcinoma, somatic PTCH1 Basal cell nevus syndrome, 109400 PTCH2-SUFU Basal cell nevus syndrome,109400 PDGFRB Basal ganglia calcification [gsdseq.ir]

Auriculoosteodysplasia

ganglia calcification • Spondyloepimetaphyseal dysplasia with joint laxity • Type IV short rib polydactyly syndrome Birth Defects A birth defect is a problem that happens [coding-pro.com]

ganglia calcification Spondyloepimetaphyseal disorder Spondyloepimetaphyseal dysplasia with joint laxity Spondyloepiphyseal dysplasia congenita group Spondyloepiphyseal dysplasia [emedcodes.com]

Metaphyseal Acroscyphodysplasia

ganglia calcification Spondyloepimetaphyseal disorder Spondyloepimetaphyseal dysplasia with joint laxity Spondyloepiphyseal dysplasia congenita group Spondyloepiphyseal dysplasia [emedcodes.com]

ganglia calcification AR Dysspondyloenchondromatosis Metachondromatosis AD Osteoglophonic dysplasia AD Genochondromatosis AD Carpotarsal osteochondromatosis AD Fibrous dysplasia [gamuts.isradiology.org]

See Insulin-dependent diabetes mellitus Idebenone, Friedreich ataxia, 1: 440 Ideopathic epilepsy, 1: 394 Idiopathic basal ganglia calcification, 1:406–407 Idiopathic parkinsonism [studfiles.net]

Raine Syndrome

Rarely, mineralisations occurred in blood-vessel walls, mainly affecting basal ganglia. [ncbi.nlm.nih.gov]

basal ganglia, falx, meninges, corpus callosum. generalized osteosclerosis, unlike in osteopetrosis and other forms of osteosclerotic dysplasia. [sites.uclouvain.be]

Radiologically, widespread bilateral calcification in the periventricular white matter, basal ganglia, and thalamus is found and in some cases calcifications are also seen [orpha.net]