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249 Possible Causes for Based on One Report of Brother and Sister, Direct Bilirubin Increased, Progressive or Intermittent Jaundice

  • Intrahepatic Cholestasis

    A 63-year-old man had a week-long history of intermittent high fever and rapidly progressive jaundice with atypical erythema.[ncbi.nlm.nih.gov] Up to 60% of patients will have elevated transaminases and 20% of patients will have increased direct bilirubin levels.[smfm.org] […] of direct bilirubin relative to total bilirubin concentration.[ncbi.nlm.nih.gov]

    Missing: Based on One Report of Brother and Sister
  • Isoniazid Hepatitis

    PubMed Citation (40 year old woman developed jaundice 8 months after starting isoniazid and taking it intermittently [bilirubin 20.4 mg/dL, AST 2500 U/L, Alk P 201 U/L], with[livertox.nih.gov] progressive liver failure and death in 10 days of admission; patient had also taken erythromycin).[livertox.nih.gov]

    Missing: Based on One Report of Brother and Sister
  • Infectious Mononucleosis Hepatitis

    Clinical jaundice was noted after the second week and lasted till the sixth week.[smj.org.sg] Clinically, the patient was continuously febrile for three weeks and had intermittent low-grade fever till the sixth week.[smj.org.sg] […] phosphatase (ALP), and gamma glutamyl transferase (GGT); and (b) serum hepatic transaminases, alanine transaminase (ALT) and aspartate transaminase (AST) as the patient’s illness progressed[smj.org.sg]

    Missing: Based on One Report of Brother and Sister
  • Cholelithiasis

    AORN J. 2003 Jun;77(6):1170-8, 1181-2; quiz 1185-8. Author information 1 Jewish Hospital, College of Nursing and Allied Health, Edwardsville, Ill, USA. Abstract Medical and surgical advances have improved the treatment of cholelithiasis (ie, gallstones) in children with sickle cell disease (SCD). Children with SCD have an[…][ncbi.nlm.nih.gov]

    Missing: Based on One Report of Brother and Sister Progressive or Intermittent Jaundice
  • Toxoplasmosis

    Parasitol Res. 2017 Jun;116(6):1603-1615. doi: 10.1007/s00436-017-5458-2. Epub 2017 May 5. Author information 1 Departamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil. 2 Departamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade[…][ncbi.nlm.nih.gov]

    Missing: Based on One Report of Brother and Sister Progressive or Intermittent Jaundice
  • Choledocholithiasis

    Still, the most statistically significant and useful predictor found in our study was a ratio of direct bilirubin to total bilirubin greater than 30%.[scielo.org.co] The presence of this predictor increased the probability of choledocholithiasis by 9.25 times (95% CI 1.20 to 65.69) and increased the probability of common bile duct dilation[scielo.org.co]

    Missing: Based on One Report of Brother and Sister Progressive or Intermittent Jaundice
  • Hemochromatosis

    Overview Hereditary hemochromatosis (he-moe-kroe-muh-TOE-sis) causes your body to absorb too much iron from the food you eat. Excess iron is stored in your organs, especially your liver, heart and pancreas. Too much iron can lead to life-threatening conditions, such as liver disease, heart problems and diabetes.[…][mayoclinic.com]

    Missing: Based on One Report of Brother and Sister Progressive or Intermittent Jaundice
  • Cholestasis

    Up to 60% of patients will have elevated transaminases and 20% of patients will have increased direct bilirubin levels.[smfm.org] AST and ALT may be increased 2 - 20 fold. Total and direct bilirubin may also be significantly elevated.[clinicaladvisor.com] Evaluation of transaminases and direct bilirubin should also be completed as these are increased in 20-60% of cases.[smfm.org]

    Missing: Based on One Report of Brother and Sister Progressive or Intermittent Jaundice
  • Acute Cholecystitis

    In the uncomplicated cholecystitis, usually there are no increase of serum total and direct bilirubin and alkaline phosphatase (cholestasis indexes).[intechopen.com]

    Missing: Based on One Report of Brother and Sister Progressive or Intermittent Jaundice
  • Portal Cirrhosis

    Laennec's cirrhosis, also known as portal cirrhosis, alcoholic cirrhosis, fatty cirrhosis, or atrophic cirrhosis, [1] is named after René Laennec, [2] a French physician and the inventor of the stethoscope. It is a disease of the liver in which the normal lobular architecture is lost, with fibrosis (scarring) and later[…][en.wikipedia.org]

    Missing: Based on One Report of Brother and Sister Progressive or Intermittent Jaundice