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156 Possible Causes for Basophilia, Thrombocytosis

  • Paraneoplastic Syndrome

    Lymphoma may be a cause of secondary thrombocytosis. Renal Paraneoplastic Syndrome About 10% patinets with idiopathic nephrotic syndrome have an underlying maligancy.[allaboutblood.com] Patients with cancer may develop pure RBC aplasia, anemia of chronic disease, leukocytosis (leukemoid reaction), thrombocytosis, eosinophilia, basophilia, and disseminated[merckmanuals.com] […] characterized by typical thrombotic and/or hemorrhagic manifestations, and sometimes leading to thrombocytopenia Thrombocytopenia may also be caused by autoantibodies; the causes of thrombocytosis[emedicine.medscape.com]

  • Myeloproliferative Disease

    One patient clearly represents a case of RARS with reactive thrombocytosis.[ncbi.nlm.nih.gov] Other criteria for the diagnosis of accelerated phase include: Peripheral basophilia greater than 20% Persistent thrombocytopenia ( 1000 x 109/L) unresponsive to therapy;[clinlabnavigator.com] As controls we considered 61 patients with reactive thrombocytosis referred to our Department in the same period of time.[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    Extreme thrombocytosis was present, although no evidence of acquired von Willebrand disorder was found.[ncbi.nlm.nih.gov] Increasing basophilia is a sign of acceleration![amboss.com] An adolescent with chronic myeloid leukemia initially presented with extreme thrombocytosis, increased megakaryopoiesis with dysmorphic features, and focal myelofibrosis in[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    A 10-year-old boy presented with spontaneous bruising and was found to have extreme thrombocytosis without neutrophilia/shift to immaturity, basophilia or eosinophilia.[ncbi.nlm.nih.gov] Three of 4 TKI-treated patients did not reach complete hematologic response due to the persistence of thrombocytosis and/or splenomegaly.[ncbi.nlm.nih.gov] In CML, the peripheral smear frequently shows immature granulocytes as well as absolute eosinophilia and basophilia.[merckmanuals.com]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Here we report a case of coexistence of BCR-ABL1 fusion gene and CALR mutation, diagnosed due to persistent thrombocytosis while the patient was in treatment-free, complete[sci.amegroups.com] Splenomegaly of more than 10 cm, basophilia and leukocytosis were associated with a shorter median survival but was not statistically significant.[ncbi.nlm.nih.gov] Diagnostic methods A histologic analysis of a peripheral smear will display immature granulocytes as well as eosinophilia and basophilia.[symptoma.com]

  • Polycythemia Vera

    Objectives: To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET).[ncbi.nlm.nih.gov] Blood CML PV Cellular Phase PMF ET RBC Normal or Normal, or , may be hypochromatic or polychromatic , teardrop cells Normal or (iron deficient anemia) WBC , left shifted, basophilia[surgpathcriteria.stanford.edu] BACKGROUND: Polycythemia vera (PV) and essential thrombocytosis (ET) are hematological disorders characterized by excessive production of mature and functional blood cells[ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    It also results in leukocytosis and thrombocytosis. On peripheral blood smear, spherocytes are unchanged or may even increase.[medcaretips.com] […] develop and cholecystectomy may be associated with an increased risk of ca colon ) d) Visible jaundice but no stones for cosmetic reasons – difficult group Post op develop thrombocytosis[ihaematology.com]

  • Acute Myelocytic Leukemia

    Here we report a case of AML with thrombocytosis arising in a patient with this syndrome.[ncbi.nlm.nih.gov] Blasts were smaller, with a predominance of small cells, scanty cytoplasm, moderate cytoplasmic basophilia, and variable cytoplasmic vacuolation. Wright stain, 1000 .[casesjournal.biomedcentral.com] In particular, the histologic distinction between the “prefibrotic” stage of PMF (a stage often associated with marked thrombocytosis in the PB and granulocytic and atypical[doi.org]

  • Ulcerative Colitis

    A complete blood count which includes anemia (hemoglobin 14 g/dL in males and 12 g/dL in females) and thrombocytosis (platelet count 350,000/µL) should be done.[symptoma.com] Other possible laboratory abnormalities include leukocytosis, thrombocytosis, and elevated acute-phase reactants (eg, ESR, C-reactive protein).[merckmanuals.com]

  • Nephrotic Syndrome

    Antiplatelet therapy was instituted with dipyridamole to prevent thromboembolism from the combination of nephrotic syndrome and thrombocytosis.[ncbi.nlm.nih.gov] Laboratory investigations showed low hemoglobin 79 g/L, low mean corpuscular volume 53 fL, thrombocytosis 973 109/L, and marked hypochromia and microcytosis, with low iron[ncbi.nlm.nih.gov]

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