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131 Possible Causes for Basophilic Stippling, Leukemia

  • Sideroblastic Anemia

    Abstract Active hairy cell leukemia is associated with an increase of RDW (Red Cell Distribution Width) which normalizes after successful therapy with 2-chlorodeoxyadenosine[ncbi.nlm.nih.gov] Showing marked anisopoikilocytosis, basophilic stippling, polychromasia and nRBCs.[imagebank.hematology.org] The biology of chronic myeloid leukemia New Engl J Med 1999 341 : 164–172 7 Koc S, Harris JW.[nature.com]

  • Acquired Idiopathic Sideroblastic Anemia

    The median survival of 19 patients not developing leukemia was 72 months for males and 42 months for females.[ncbi.nlm.nih.gov] stippling, reticulocytes with impaired heme synthesis, delta ALA synthetase and protease activity Treatment Pyridoxine is often administered, usually without therapeutic[medical-dictionary.thefreedictionary.com] The peripheral blood may present with a dimorphic RBC population in which anisocytosis, poikilocytosis, hypochromia, and basophilic stippling may be observed.[medlabsc.blogspot.com]

  • Myelodysplasia

    Therapy-related leukemia (myelodysplasia and acute myeloid leukemia-t-MDS/AML) is a well-known complication of conventional chemoradiotherapy used to treat a variety of primary[ncbi.nlm.nih.gov] stippling, erythrocyte vacuoles, nucleated red blood cells, Howell-Jolly bodies Granulocytes : neutropenia with immature, hypogranular forms, pseudo-Pelger-Huet neutrophils[pathologyoutlines.com] Juvenile myelomonocytic leukemia (JMML) is a rare aggressive childhood leukemia characterized by an excess proliferation of cells of granulocytic and monocytic lineages.[ncbi.nlm.nih.gov]

  • Acquired Sideroblastic Anemia

    […] or Acute Lymphocytic Leukemia Completed NCT00462605 Phase 2 entinostat;sargramostim 21 Thalidomide in Treating Patients With Myelodysplastic Syndrome Completed NCT00015990[malacards.org] Anisocytosis (increased RDW) due to microcytic and normocytic RBCs and basophilic stippling are common.[med-ed.virginia.edu] The patient was followed for 45 months and no signs of chronic myeloid leukemia or other leukemic transformation developed. In IASA the chromosomal changes are variable.[ncbi.nlm.nih.gov]

  • Refractory Anemia with Excess Blasts in Transformation

    We treated 372 patients with AML (acute promyelocytic leukemia [APL] excluded), 106 with RAEB-t, and 52 with RAEB.[ncbi.nlm.nih.gov] stippling Poikilocytosis Varying shapes, frequently macro-ovalocytes Bone marrow erythroid lineage abnormalties Erythroid hyperplasia or hypoplasia Megaloblastoid / megaloblastic[surgpathcriteria.stanford.edu] […] recently proposed World Health Organization Classification of Hematologic Malignancies eliminated this category from MDS by lowering the blast count cutoff for acute myeloid leukemia[ncbi.nlm.nih.gov]

  • Leukemia

    There are basically 4 types of leukemia, namely: Acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia and chronic myeloid leukemia.[symptoma.com] stippling in younger red cells.[ncbi.nlm.nih.gov] Thus, the four major types of leukemia are: Acute Lymphocytic Leukemia Chronic Lymphocytic Leukemia Acute Myelogenous Leukemia Chronic Myelogenous Leukemia Acute leukemia[web.archive.org]

  • Refractory Anemia

    A 72-year-old man with refractory anemia with an excess of blasts developed overt leukemia with leukothrombocytosis.[ncbi.nlm.nih.gov] stippling.[ijcasereportsandimages.com] Erythrodysplasia consists of irregular nuclear contours and nuclear budding as well as significant coarse basophilic stippling and irregular hemoglobinization of the cytoplasm[gpec.ubc.ca]

  • Dysmyelopoietic Syndrome

    When compared with patients with de novo leukemia and DMS, the chromosomal abnormalities in these patients are more complex and extensive.[ncbi.nlm.nih.gov] Blood film characteristically shows dimorphic red cells, Pappenheimer bodies, basophilic stippling, dysplasia evidenced as erythrocytes with anisocytosis (varying sizes) and[patient.info] Abstract Abnormalities of the short arm of chromosome #12 (12p) were found in 18 patients, 7 with previously untreated acute nonlymphocytic leukemia (ANLL) and 11 with dysmyelopoietic[ncbi.nlm.nih.gov]

  • Idiopathic Refractory Anemia

    Attention is paid to the hematological changes prior to leukemia development.[link.springer.com] stippling and Pappenheimer bodies; no dysplastic changes, minimal neutropenia, no myeloblasts, no monocytosis, no thrombocytopenia Bone marrow general : hypercellular or[pathologyoutlines.com] stippling Pappenheimer bodies Bone marrow Erythroid hyperplasia Large numbers of sideroblasts and ringed sideroblasts Increased hemosiderin Increased serum iron Normal or[5minuteconsult.com]

  • Acute Erythroblastic Leukemia

    This report describes two elderly patients with acute leukemia in which blast cells were undifferentiated with conventional light microscopy (L.M.) and cytochemistry.[ncbi.nlm.nih.gov] Above the blast cell at lower right is a lymphocyte and a red cell with basophilic stippling. At lower left is any erythroblast with a band neutrophil above it.[meds.com] stippling (panel C, red arrow).[imagebank.hematology.org]

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