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131 Possible Causes for Basophilic Stippling, Leukemia

  • Sideroblastic Anemia

    Abstract Active hairy cell leukemia is associated with an increase of RDW (Red Cell Distribution Width) which normalizes after successful therapy with 2-chlorodeoxyadenosine[] Showing marked anisopoikilocytosis, basophilic stippling, polychromasia and nRBCs.[] The biology of chronic myeloid leukemia New Engl J Med 1999 341 : 164–172 7 Koc S, Harris JW.[]

  • Acquired Idiopathic Sideroblastic Anemia

    The median survival of 19 patients not developing leukemia was 72 months for males and 42 months for females.[] stippling, reticulocytes with impaired heme synthesis, delta ALA synthetase and protease activity Treatment Pyridoxine is often administered, usually without therapeutic[] The peripheral blood may present with a dimorphic RBC population in which anisocytosis, poikilocytosis, hypochromia, and basophilic stippling may be observed.[]

  • Myelodysplasia

    Therapy-related leukemia (myelodysplasia and acute myeloid leukemia-t-MDS/AML) is a well-known complication of conventional chemoradiotherapy used to treat a variety of primary[] stippling, erythrocyte vacuoles, nucleated red blood cells, Howell-Jolly bodies Granulocytes : neutropenia with immature, hypogranular forms, pseudo-Pelger-Huet neutrophils[] Juvenile myelomonocytic leukemia (JMML) is a rare aggressive childhood leukemia characterized by an excess proliferation of cells of granulocytic and monocytic lineages.[]

  • Acquired Sideroblastic Anemia

    […] or Acute Lymphocytic Leukemia Completed NCT00462605 Phase 2 entinostat;sargramostim 21 Thalidomide in Treating Patients With Myelodysplastic Syndrome Completed NCT00015990[] Anisocytosis (increased RDW) due to microcytic and normocytic RBCs and basophilic stippling are common.[] The patient was followed for 45 months and no signs of chronic myeloid leukemia or other leukemic transformation developed. In IASA the chromosomal changes are variable.[]

  • Refractory Anemia with Excess Blasts in Transformation

    We treated 372 patients with AML (acute promyelocytic leukemia [APL] excluded), 106 with RAEB-t, and 52 with RAEB.[] stippling Poikilocytosis Varying shapes, frequently macro-ovalocytes Bone marrow erythroid lineage abnormalties Erythroid hyperplasia or hypoplasia Megaloblastoid / megaloblastic[] […] recently proposed World Health Organization Classification of Hematologic Malignancies eliminated this category from MDS by lowering the blast count cutoff for acute myeloid leukemia[]

  • Leukemia

    There are basically 4 types of leukemia, namely: Acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia and chronic myeloid leukemia.[] stippling in younger red cells.[] Thus, the four major types of leukemia are: Acute Lymphocytic Leukemia Chronic Lymphocytic Leukemia Acute Myelogenous Leukemia Chronic Myelogenous Leukemia Acute leukemia[]

  • Refractory Anemia

    A 72-year-old man with refractory anemia with an excess of blasts developed overt leukemia with leukothrombocytosis.[] stippling.[] Erythrodysplasia consists of irregular nuclear contours and nuclear budding as well as significant coarse basophilic stippling and irregular hemoglobinization of the cytoplasm[]

  • Dysmyelopoietic Syndrome

    When compared with patients with de novo leukemia and DMS, the chromosomal abnormalities in these patients are more complex and extensive.[] Blood film characteristically shows dimorphic red cells, Pappenheimer bodies, basophilic stippling, dysplasia evidenced as erythrocytes with anisocytosis (varying sizes) and[] Abstract Abnormalities of the short arm of chromosome #12 (12p) were found in 18 patients, 7 with previously untreated acute nonlymphocytic leukemia (ANLL) and 11 with dysmyelopoietic[]

  • Idiopathic Refractory Anemia

    Attention is paid to the hematological changes prior to leukemia development.[] stippling and Pappenheimer bodies; no dysplastic changes, minimal neutropenia, no myeloblasts, no monocytosis, no thrombocytopenia Bone marrow general : hypercellular or[] stippling Pappenheimer bodies Bone marrow Erythroid hyperplasia Large numbers of sideroblasts and ringed sideroblasts Increased hemosiderin Increased serum iron Normal or[]

  • Acute Erythroblastic Leukemia

    This report describes two elderly patients with acute leukemia in which blast cells were undifferentiated with conventional light microscopy (L.M.) and cytochemistry.[] Above the blast cell at lower right is a lymphocyte and a red cell with basophilic stippling. At lower left is any erythroblast with a band neutrophil above it.[] stippling (panel C, red arrow).[]

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