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240 Possible Causes for Behavior Problem, Progressive Mental Retardation, Spasticity - Hyperreflexia

  • Mental Retardation

    Affected males showed mild mental retardation, microcephaly, hyperreflexia or spastic diplegia, and a similar facial appearance, including a triangular face, prognathism,[] Brachydactyly mental retardation syndrome (BDMR) is an autosomal dominant disorder, caused by haploinsufficiency of histone deacetylase 4 (HDAC4), also on chromosome 2q37.[] Abstract Smith-Magenis syndrome (SMS) is a rare syndrome with multiple congenital malformations, including development and mental retardation, behavioral problems and a distinct[]

  • Hallervorden-Spatz Syndrome

    Described features include 9,11 : progressive dementia extrapyramidal signs (rigidity, dystonia, choreoathetosis) corticospinal signs (spasticity, hyperreflexia) dysarthria[] It is characterized by progressive Parkinson-like rigidity, athetotic movements, and progressive mental and emotional retardation.[] Additionally, affected individuals may experience a loss of intellectual function (dementia) and psychiatric symptoms such as behavioral problems, personality changes, and[]

  • Pelizaeus-Merzbacher Disease

    There is gross spasticity, hyperreflexia and extensor plantar response. In severe cases, the child is unable to sit unsupported and is certainly unable to walk.[] retardation is not severe, some patients show dementia or personality disorders, the disease is progressive rather than static in some, and several females show signs of[] That means children can have many problems, including: Balance and mobility problems Behavioral and learning disabilities Bladder issues Breathing difficulties Developmental[]

  • Globoid Cell Leukodystrophy

    Spasticity. Hyperreflexia. Clonus. Pyramidal paresis of limb or limbs. Extensor plantar responses. Unsteadiness of gait. Psychomotor retardation. Dysphagia. Deafness.[] This metabolic disorder is characterized by progressive neurological dysfunction such as mental retardation, paralysis, blindness, deafness and paralysis of certain facial[] Patients with later onset forms usually present with ataxia, weakness, blindness, spastic paraparesis, behavioral problems, and dementia.[]

  • Richards-Rundle Syndrome

    In addition to the three principal signs, abnormal gait, hypogonadism, amyotrophy or muscle agenesis, hyperreflexia, hypertonia or spasticity, osteoporosis, and restricted[] progressive spasticity, X-linked, Mental retardation, X-linked, with cerebellar hypoplasia and distinctive facial appearance, Metachromatic Leukodystrophy, Miller Fisher[] Psychiatric Disorders and Behavioral Problems in Children with ... ; Children with Velocardiofacial Syndrome: Usefulness ... least 1 per 2000 to 4500 live births (Tezenas[]

  • Lesch Nyhan Syndrome

    In LNS patients there are three major signs of pyramidal dysfunction: spasticity, hyperreflexia and the extensor plantar reflex (also known as the Babinski reflex: the great[] Affected boys have mental retardation, delayed development, extrapyramidal motor disturbances and self-injuring behavior.[] problems, which can be best addressed by using behavioral modification techniques.[]

  • Tay-Sachs Disease

    […] of the body and arching of the back), the cherry-red spot on the retina, seizures, blindness, deafness, and spasticity.[] It is characterized by progressive mental and physical retardation and early death.[] Behavioral problems a progressive loss of speech, life skills, and intellectual abilities also develop. Children may or may not develop a cherry-red spot in the eyes.[]

  • Chudley-Rozdilsky Syndrome

    […] with hyperreflexia, cerebellar dysfunction, short stature, Hirschsprung's disease, pharyngeal web, and facial dysmorphism" described in a case report by Kim et al..[] Mental retardation, progressive Progressive mental retardation [ more ] 0006887 Lumbar hyperlordosis Excessive inward curvature of lower spine 0002938 Myopathy Muscle tissue[] Fragility Intellectual Developmental Disorder with Abnormal Behavior, Microcephaly, and Short Stature INTELLECTUAL DEVELOPMENTAL DISORDER WITH CARDIAC ARRHYTHMIA Intellectual[]

  • Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

    This feature can vary from lower limb hyperreflexia with positive Babinski sign, with or without gait abnormalities, to a clear picture of spastic paraparesis.[] retardation, progressive spastic paraparesis, seizures, and myoclonus epilepsy.[] Further symptoms comprise intolerance of protein-rich food, ataxia and spasticity, mood swings and behavioral problems.[]

  • Metachromatic Leukodystrophy

    60 33 frequent (33%) Frequent (79-30%) HP:0001257 16 hyperreflexia 60 33 frequent (33%) Frequent (79-30%) HP:0001347 17 joint stiffness 60 33 frequent (33%) Frequent (79-[] One of the two un-transplanted controls, 15 years after MLD diagnosis, has relentlessly progressed to full dependency with epilepsy, severe mental retardation, dystonic movements[] The initial presentation includes behavioral problems, intellectual impairment, gait disturbance, incontinence, and peripheral neuropathy.[]

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