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24 Possible Causes for Behavior Problem, Spasticity - Hyperreflexia, Vibratory Sensation Decreased

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[icdlist.com]

  • Subacute Combined Degeneration of Spinal Cord

    Neurological findings include numbness, loss of vibratoty and joint position sense, sense of proprioception, hyperreflexia, spasticity, weakness and extensor plantar responses[ispub.com] Posterior column dysfunction decreases vibratory sensation and proprioception (joint sense).[en.wikipedia.org] He had hyperreflexia, bilateral Babinski signs and absent ankle jerks. Tone was spastic.[neurology.org]

  • Machado-Joseph Disease

    MJD Type 1 patients generally present with cerebellar signs and external progressive ophthalmoplegia with variable degrees of pyramidal manifestations (spasticity, hyperreflexia[orpha.net] The symptoms included abnormal behavior, excitation, an uncooperative attitude, crying, disorientation, slow thought processes, hallucinations, and delusions.[ncbi.nlm.nih.gov] SCA3 type 1 (MJD Type 1, see this term) is associated with ataxia, ophthalmoparesis, pyramidal signs such as spasticity and hyperreflexia, and extrapyramidal signs including[orpha.net]

  • Friedreich Ataxia

    His examination was significant for spastic gait, hyperreflexia, and sensory neuropathy. Genetic testing revealed a compound heterozygous mutation in the FXN gene.[ncbi.nlm.nih.gov] problems and psychiatric symptoms.[investors.biomarin.com] The clinical picture consisted of progressive spastic gait, truncal and limb ataxia, dysarthria, nystagmus, hyperreflexia with knee and ankle clonus and extensor plantar response[ncbi.nlm.nih.gov]

  • Autosomal Recessive Spastic Paraplegia Type 46

    Affiliated tissues include brain , and related phenotypes are nystagmus and hyperreflexia Disease Ontology : 12 A hereditary spastic paraplegia that has material basis in[malacards.org] […] in the lower limbs Decreased lower limb vibratory sense Decreased vibratory sense in lower limbs Decreased vibratory sense in the lower extremities Decreased vibratory sense[rarediseases.info.nih.gov] Another five patients had behavioral problems in childhood. Brain MRIs from nine patients were available for review.[nature.com]

  • Spastic Paraplegia

    This case showed spasticity and hyperreflexia with pathological reflexes and ankle clonus as well as muscle weakness in all extremities.[ncbi.nlm.nih.gov] This is often accompanied by brisk reflexes, extensor plantar responses, decreased vibratory sensation in the toes, and pes cavus.[now.aapmr.org] Another five patients had behavioral problems in childhood. Brain MRIs from nine patients were available for review.[nature.com]

  • Autosomal Dominant Spastic Paraplegia Type 31

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] sensation Progressive Pes cavus Skeletal muscle atrophy Abnormal cerebellum morphology Rare Symptoms - Less than 30% cases Brisk reflexes External ophthalmoplegia Adult onset[mendelian.co] problems and slowly progressive dementia (frontal or subcortical in nature).[neuroweb.us]

  • Pallidopyramidal Syndrome

    […] and hyperreflexia, and hemiplegic gait.[neurologyindia.com] sensation Decreased motor nerve conduction velocity Toe walking Urinary urgency Onion bulb formation Neurogenic bladder Upgaze palsy Irritability Impulsivity Muscle stiffness[mendelian.co] […] disorder (RBD), hallucinations and thinking problems which can lead to dementia.[medium.com]

  • Spastic Quadriplegic Cerebral Palsy Type 2

    People with this form of spastic paraplegia can also experience exaggerated reflexes (hyperreflexia) in the arms; speech difficulties (dysarthria); difficulty swallowing ([icdlist.com] Vibratory sensation was decreased, and a socklike hypoesthesia to pinprick and light touch was noted. A muscle biopsy showed atrophic and angulated fibers.[nejm.org] : Seizures Vision, hearing, or speech problems Learning disabilities and behavior problems Intellectual disability Respiratory problems Bowel and bladder problems Bone abnormalities[stanfordchildrens.org]

  • Autosomal Recessive Spastic Paraplegia Type 21

    Neurological examination also showed the classic spastic paraplegia symptoms such as proximal weakness of the lower limbs and profound proximal spasticity.[omicsonline.org] vibratory sense Cerebellar signs Neurologic examination demonstrating EITHER of the following: A pure phenotype of spastic paraplegia with hyperreflexia, extensor plantar[ncbi.nlm.nih.gov] Another five patients had behavioral problems in childhood. Brain MRIs from nine patients were available for review.[nature.com]

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