Beta Thalassaemia Major: Causes & Reasons

Possible Causes for Beta Thalassaemia Major

(carrier) and beta thalassaemia major. [ukts.org]

Subgroup: Beta thalassaemia Beta-thalassaemia major (intermedia) is a disorder of haemoglobin, a major component of the red blood cells. [enerca.org]

Thalassaemia can take several forms. The most common is beta thalassaemia major. [healthtalk.org]

Beta Thalassemia

A total of 85 Italian beta-thalassaemia major participants and 73 controls completed an ad hoc questionnaire. [journals.sagepub.com]

Thalassaemia can take several forms. The most common is beta thalassaemia major. [healthtalk.org]

Beta-thalassaemia major participants reported higher scores on job satisfaction, self-esteem and self-description. [journals.sagepub.com]

Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia Other names Autoimmune haemolytic anaemia Specialty Hematology Autoimmune hemolytic anemia (AIHA) occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in the[…] [en.wikipedia.org]

Thalassemia Minor

Sometimes, two genes being faulty leads to a more serious form of thalassaemia called beta thalassaemia major. [babycentre.co.uk]

If this happens the child may develop medical problems associated with beta thalassaemia intermedia or beta thalassaemia major. [ukts.org]

There are a number of types of thalassaemia, which can be divided into alpha and beta thalassaemias. Beta thalassaemia major is the most severe type. [nhs.uk]

Beta-Thalassemia Associated with Another Hemoglobin Anomaly

Thalassaemia can take several forms. The most common is beta thalassaemia major. [healthtalk.org]

There are different types of thalassaemia, which can be divided into alpha and beta thalassaemias. Beta thalassaemia major is the most severe type. [nhs.uk]

Subgroup: Delta beta thalassaemia Is a disorder of haemoglobin, a major component of the red blood cells. [enerca.org]

Hemoglobin E-Thalassemia

If this happens the child may develop medical problems associated with beta thalassaemia intermedia or beta thalassaemia major. [ukts.org]

There are different types of thalassaemia, which can be divided into alpha and beta thalassaemias. Beta thalassaemia major is the most severe type. [nhs.uk]

2/ I am going to do the CVS as my GP's suggestion, can the Hb E/ beta thalassaemia major children can have the normal life and grow healthily? [thalassemiapatientsandfriends.com]

Thalassemia

English who suffer from an inherited disease called beta thalassaemia major and who receive frequent blood transfusions to treat it. [mymemory.translated.net]

There are different types of thalassaemia, which can be divided into alpha and beta thalassaemias. Beta thalassaemia major is the most severe type. [nhs.uk]

The family, from Cadiz in southern Spain, had their first child, Andres, only to discover that he suffered from a rare hereditary disease called Beta Thalassaemia major. [web.archive.org]

Hemoglobin Bart's Disease

Sometimes, two genes being faulty leads to a more serious form of thalassaemia called beta thalassaemia major. [babycentre.co.uk]

The more severe beta types are beta thalassaemia major (BTM) and beta thalassaemia intermedia (BTI). [patient.info]

Survival in beta-thalassaemia major in the UK: data from the UK Thalassaemia Register. Lancet. 2000;355(9220):2051–2052. 12. Eldor A, Rachmilewitz EA. [aafp.org]

Alpha-Thalassemia

Beta thalassaemia - major. United Kingdom Thalassaemia Society. www.ukts.org [Accessed June 2015 [babycentre.co.uk]

There are different types of thalassaemia, which can be divided into alpha and beta thalassaemias. Beta thalassaemia major is the most severe type. [nhs.uk]

Beta-thalassaemia major is more common than alpha-thalassaemia major. [betterhealth.vic.gov.au]

Thalassaemia-Haemoglobin C Disease

The prevention of homozygous beta thalassaemia major requires persons with beta thalassaemia trait avoiding having children with someone else with the beta thalassaemia trait [star2.com]

It can cause thalassaemia major or intermedia hen coinherited with beta thalassaemia. [nhsggc.org.uk]

Inclusion Term For Icd 10 Code D57.2 Hb-SC disease Hb-S/Hb-C disease SNOMed Terms: Beta + thalassaemia Beta + thalassemia Beta plus thalassaemia Beta plus thalassemia beta [medicbind.com]

Juvenile Colloid Milium

Giordano G, Ricci R, Froio E, Izzi G, Barone A, et al. (2008) A case of colloid milium in patient with beta thalassaemia major. J Cutan Pathol 35: 566-569. [avensonline.org]

thalassaemia major. [link.springer.com]

Int J Dermatol 33:793–795 CrossRef PubMed Google Scholar Giordano G, Ricci R, Froio E, Izzi G, Barone A, Boccaletti V (2008) A case of colloid milium in patient with beta [link.springer.com]

Acute Erythroleukemia

thalassaemia major) and from eritremia ad andamento acuto (acute erythraemia, acute erythraemic myelosis or Di Guglielmo's disease) ( Nolli & Benario, 1936 ; Di Guglielmo [onlinelibrary.wiley.com]

[…] terminology was used in the same year by Nolli & Benario in an article in which they sought to distinguish the morbo di Vaquez ( polycythaemia vera) from Cooley's anaemia (beta [onlinelibrary.wiley.com]

Sickle Cell - Beta-Thalassemia

Thalassaemia can take several forms. The most common is beta thalassaemia major. [healthtalk.org]

Beta Thalassaemia Major Beta Thalassaemia Major is a serious anaemia affecting people who have inherit two Beta Zero Thalassaemia genes ( β 0Thal β 0Thal ) one from each parent [sickle-thal.nwlh.nhs.uk]

Patients with beta thalassaemia major suffer from zinc deficiency which could be seen as one of the causes of delayed maturity. [cochranelibrary.com]

Sickle Cell Thalassemia Disease

Thalassaemia can take several forms. The most common is beta thalassaemia major. [healthtalk.org]

There are a number of types of thalassaemia, which can be divided into alpha and beta thalassaemias. Beta thalassaemia major is the most severe type. [nhs.uk]

Living with beta thalassaemia major & intermedia People who are making decisions about screening and diagnosis for beta thalassaemia often ask what life would be like for [healthtalk.org]

Congenital Neutropenia - Myelofibrosis - Nephromegaly Syndrome

This study is aimed to estimate the prevalence of blood TTI in multiple blood transfused patients of beta thalassaemia major. [citeulike.org]

Abstract Transfusion Transmitted Infection (TTI) continue to be a problem in many parts of world and multi-transfused patients of beta thalassaemia major are at a particularly [citeulike.org]

Cross-sectional study of 200 multi-transfused patients of beta thalassaemia major, who were interviewed using a structured questionnaire and history was taken regarding sero-status [citeulike.org]

Hemoglobin Lepore-Beta-Thalassemia Syndrome

[…] erythropoiesis § Alpha § Beta § Delta-beta § Gamma-delta-beta Thalassaemia major § Transfusion dependant Thalassaemia intermedia § Anaemia and splenomegaly Thalassaemia trait [ihaematology.com]

If your baby’s biological father is a beta thalassaemia carrier, there is a 1 in 4 (25%) chance that your baby could inherit thalassaemia major (the specific condition is [gov.uk]

Subgroup: Delta beta thalassaemia Is a disorder of haemoglobin, a major component of the red blood cells. [enerca.org]

Hemochromatosis-Related Cardiomyopathy

Modell B, Khan M, Darlison M (2000) Survival in beta-thalassaemia major in the UK: data from the UK Thalassaemia Register. Lancet 355: 2051-2052. [omicsonline.org]

Early iron overload in beta-thalassaemia major: when to start chelation therapy? Archives of Diseases of Childhood 57, 929. [sickle.bwh.harvard.edu]

Multiple frequent blood transfusions [2] (either whole blood or just red blood cells ), which are usually needed either by individuals with hereditary anaemias (such as beta-thalassaemia [en.wikipedia.org]

Renal Embolism

thalassaemia major. [anzsnasm.com]

Asian, renal transplant patient presented to the Emergency Department with sudden onset, pleuritic chest pain associated with shortness of breath, on a background history beta [anzsnasm.com]

Pseudoxanthoma Elasticum

Development of an acquired systemic elastopathy resembling pseudoxanthoma elasticum in patients with chronic haemoglobinopathies such as beta thalassaemia major and sickle [ncbi.nlm.nih.gov]

[…] patients. 61 Hamlin N...Le Saux O 12930400 2003 8 Arterial elastorrhexis: manifestation of a generalized elastic tissue disorder in beta-thalassaemia major. 61 Tsomi K... [malacards.org]

Increased elastic tissue and solar elastotic syndromes. 61 Lewis KG...Robinson-Bostom L 15243519 2004 7 Acquired Pseudoxanthoma elasticum-like syndrome in beta-thalassaemia [malacards.org]

Arthrogryposis, Perthes Disease and Upward Gaze Palsy

Severe haemophilia A and B (classic haemophilia and Christmas disease) -- Red cell membrane abnormalities -- Hereditary elliptocytosis -- Hereditary spherocytosis -- Beta-thalassaemia [worldcat.org]

major -- Sickle cell disease -- Glucose-6 -- phosphate dehydrogenase deficiency -- Pyruvate kinase deficiency -- Further reading -- ch. 12 Oncology -- Introduction -- Renal [worldcat.org]

Plasmodium Knowlesi

A 23-year old splenectomized patient with beta thalassaemia major presented with fever 11 days after receiving a blood transfusion from a pre-symptomatic donor who presented [ncbi.nlm.nih.gov]

CASE PRESENTATION: A 23-year old splenectomized patient with beta thalassaemia major presented with fever 11 days after receiving a blood transfusion from a pre-symptomatic [dr.ntu.edu.sg]

Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: a case report. Malar J 15: 357. [ajtmh.org]

Milium

Thus, this case represents the first case of CM associated with beta thalassaemia major. [ncbi.nlm.nih.gov]

A case of colloid milium in patient with beta thalassaemia major. J Cutan Pathol 2008 Jun; 35(6): 566-569. [PubMed]. 13. [escholarship.org]

In this paper, we report an interesting case of adult CM in a transfused patient affected by beta thalassaemia major. [ncbi.nlm.nih.gov]

Sickle Cell - Hemoglobin E

Right ventricular cardiomyopathy in beta-thalassaemia major. Eur Heart J 2002 ;23: 147 - 156 27. Derchi G, Fonti A, Forni GL, et al. [nejm.org]

[…] do not cause a major public health problem except for the case of hemoglobin E beta-thalassaemia 8 9. [slideshare.net]

Pulmonary hypertension in patients with thalassemia major. Am Heart J 1997 ;134: 532 - 537 26. [nejm.org]

Hemoglobin E Disease

PubMed View Article Google Scholar Karnon J, Zeuner D, Brown J, Ades AE, Wonke B, Modell B: Lifetime treatment costs of beta-thalassaemia major. [bmcresnotes.biomedcentral.com]

[…] do not cause a major public health problem except for the case of hemoglobin E beta-thalassaemia 8 9. [slideshare.net]

See also the term: “Beta-thalassaemia”. What causes the disease and how common is it? This is a genetic disease. [enerca.org]

Graft Rejection

A 13-year old girl suffering from beta-thalassaemia major received bone marrow transplantation (BMT) from her HLA identical bother. [ncbi.nlm.nih.gov]

Megaloblastic Anemia in Pregnancy

Mutation of both genes (beta thalassaemia major) results in a severe transfusion dependent anaemia. [bpac.org.nz]

Obstet Gynecol 91:662, 1998 [PubMed: 9572207] Daskalakis GJ, Papageorgiou IS, Antsaklis AJ, et al: Pregnancy and homozygous beta thalassaemia major. [accessmedicina.mhmedical.com]

In general, people with a single mutated gene (beta thalassaemia minor/trait) have mild anaemia with marked hypochromic microcytosis (MCV 60 – 75 fL). [bpac.org.nz]

Iron Poisoning

Modell B, Khan M, Darlison M (2000) Survival in beta-thalassaemia major in the United Kingdom: data from the UK Thalassaemia Register. Lancet 3:2051-2. [europeanmedical.info]

Barman Balfour JA, Foster RH (1999) Deferiprone: a review of its clinical potential in iron overload in beta thalassemia major and other transfusion-dependent diseases. [europeanmedical.info]

Anderson LJ, Wonke B, Prescott E etal. (2002) Improved myocardial iron levels and ventricular function with oral deferiprone compared with subcutaneous desferrioxamine in thalassaemia [europeanmedical.info]

Pericardial Effusion

Register Massive haemorrhagic pericardial effusion in beta-thalassaemia major - 24 Hours access EUR €36.00 GBP £28.00 USD $45.00 Rental This article is also available for [academic.oup.com]

Deferoxamine

Modell, “The Pathophysiology of Beta-Thalassaemia Major,” Journal of Clinical Pathology. Supplement (Royal College of Pathologists), Vol. 8, 1974, pp. 12-18. [ 31 ] A. [scirp.org]

View Article PubMed Google Scholar Modell B, Khan M, Darlison M: Survival in beta-thalassaemia major in the UK: data from the UK Thalassaemia Register. [jcmr-online.biomedcentral.com]

Bejaouie and A. di Mileda, “Oxidant, Antioxidant Status and Metabolic Data in Patients with Beta-Thalassemia,” Clinica Chimica Acta, Vol. 338, No. 1-2, 2003, pp. 79-86. doi [scirp.org]

Cerebral Thrombosis

Cerebral venous thrombosis in infants and children Mahendranath D Moharir MD MSc (Dr. Moharir of the University of Toronto has no relevant financial relationships to disclose.) Gabrielle deVeber MD MHSc (Dr. deVeber of the University of Toronto has no relevant financial relationships to disclose.) Bernard L Maria[…] [medlink.com]