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4,268 Possible Causes for beta1, cAMP dependent, kinase,, mouse, protein, regulatory, subunit

Did you mean: beta1, cAMP, dependent, kinase, mouse, protein, regulatory, subunit

  • Isoproterenol

    HDAC6 expression was increased by treatment with selective activators of cAMP-dependent protein kinase (PKA) or exchange protein activated by cAMP (Epac).[ncbi.nlm.nih.gov] We characterized the changes in cardiac structure and function in response to chronic isoproterenol infusion using echocardiography in a panel of 104 inbred mouse strains.[ncbi.nlm.nih.gov] -3-kinase/AKT pathway was required to trigger the GSK3β pathway.[ncbi.nlm.nih.gov] Isoproterenol non-selectively binds and stimulates beta1 and beta2 adrenergic receptors. There is little activity on alpha receptors.[pathwaymedicine.org] We conducted experiments to identify the mechanisms involved in the regulatory functions of adrenergic signaling on erythroid differentiation and the expression of hemoglobin[ncbi.nlm.nih.gov] In contrast, β2 subunit protein levels decreased (down to 49%), while mRNA levels remained unchanged.[ncbi.nlm.nih.gov] Vascular Medicine, Peking University Third Hospital, Beijing Key Laboratory of Cardiovascular Receptors Research, Key Laboratory of Cardiovascular Molecular Biology and Regulatory[ncbi.nlm.nih.gov]

  • Carbachol

    There seem to be distinct secretion pathways for muscarinic or cAMP-dependent stimulation of mucin secretion.[ncbi.nlm.nih.gov] […] borate (2-APB, 300 microM), which impairs inositol trisphosphate (IP3)-induced release of Ca2 , reduced carbachol responses in human detrusor to 60%, in pig to 35% and in mouse[ncbi.nlm.nih.gov] […] to protein kinase C (PKC) zeta, and by the p70S6K inhibitor rapamycin.[ncbi.nlm.nih.gov] Abstract The TAO (for thousand-and-one amino acids) protein kinases activate p38 mitogen-activated protein (MAP) kinase cascades in vitro and in cells by phosphorylating the[ncbi.nlm.nih.gov] We further describe the protein expression of smooth muscle myosin and its regulatory kinase, the myosin light chain kinase, in human and bovine trabecular meshwork cells.[ncbi.nlm.nih.gov] Cells in parallel wells were harvested for immunoblot analysis of G protein alpha-subunit expression.[ncbi.nlm.nih.gov] BACKGROUND: Neuronal excitability is in part determined by Ca2 availability that is controlled by regulatory mechanisms of cytosolic Ca2 ([Ca2 ]cyt).[ncbi.nlm.nih.gov]

  • Probucol

    […] polyphenol, dithioketal ( CHEBI:8427 ) Targets Kind Protein Organism Humans Pharmacological action Yes Actions Inhibitor General Function Syntaxin binding Specific Function cAMP-dependent[drugbank.ca] Although AGI1067 did not have marked lipid-lowering effects in two transgenic mouse models (the LDL-receptor-deficient and apolipoprotein-E-deficient models) fed a high-fat[ncbi.nlm.nih.gov] In this study, human mesangial cells (HMCs) treated with high glucose showed the above-mentioned features through the activation of Janus kinase 2 (JAK2)/signal transducers[ncbi.nlm.nih.gov] Abstract Probucol, an antioxidative and hypolipidemic agent, has been postulated to increase reverse cholesterol transport by enhancing cholesteryl ester transfer protein[ncbi.nlm.nih.gov] Utility Menu Contact Helpful Links News and Notices Login Provinces Canadian Pharmacy Regulatory Authorities AB BC MB NB NL NS NT NU ON PE QC SK YT All Search Main navigation[napra.ca] Abstract The hERG gene encodes the pore-forming α-subunit of the rapidly activating delayed rectifier potassium channel (I Kr), which is important for cardiac repolarization[ncbi.nlm.nih.gov] Based on Western blot analyses, probucol decreased the expression of phospho-mitogen-activated protein kinase kinases 1 (p-MEK1) and phospho-ERK1/2 and enhanced the expression[ncbi.nlm.nih.gov]

  • Nasal Polyp

    Further, using a fungal allergen challenge mouse model, we detected greatly reduced Th2 cytokine-producing and Ki-67 proliferating lung ILC2s in mice receiving dexamethasone[ncbi.nlm.nih.gov] OPN induced VEGF production by DNPCs in a time- and dose-dependent manner through phosphatidylinositol 3-kinase- protein kinase B and the extracellular signal-regulated kinase[ncbi.nlm.nih.gov] Treatment with TGF-beta1 with or without TSA did not have cytotoxic effect.[ncbi.nlm.nih.gov] Mucosal Treg cells coexpressed both proteins.[ncbi.nlm.nih.gov] The transcriptional expression of three subunits of ENaC was in the following order: α β γ, in both groups.[ncbi.nlm.nih.gov] Naringenin only suppressed the expression of extracellular signal-regulated protein kinase (pERK)1/2 among evaluated signaling molecules.[ncbi.nlm.nih.gov] BACKGROUND: To elucidate the interaction between hypoxia-induced autophagy and glycolysis in nasal polyp fibroblasts, and the regulatory role of Sirtuin 6 (SIRT6) in the pathogenesis[ncbi.nlm.nih.gov]

    Missing: cAMP dependent
  • Mycobacterium Bovis

    Fecal swabs, tracheal swabs, and tracheal lavages of 76 banded mongooses caught in cage traps within a 2-km radius of Skukuza Rest Camp were submitted for Mycobacterium culture[ncbi.nlm.nih.gov] In addition, the fusion proteins LT40 and LT70 consisting of multistage antigens showed promising therapeutic effects in the mouse model.[ncbi.nlm.nih.gov] The Rho-associated protein kinase (ROCK) inhibitor Y-27632 (1 μM) was used to assess the mechanism by which WPC enhanced BCG uptake.[ncbi.nlm.nih.gov] Two unrelated patients had different homozygous interleukin-12 receptor beta1 subunit gene splice-site mutations (64 5G-- A and 550-2A-- G).[ncbi.nlm.nih.gov] We identified species-specific variants in 20 regulatory proteins and confirmed differential expression of hypoxia-related genes between M. bovis and M. tuberculosis. 2016[ncbi.nlm.nih.gov] The pyruvate requirement of some members of the Mycobacterium tuberculosis complex is due to an inactive pyruvate kinase: implications for in vivo growth. Mol.[lgcstandards-atcc.org] [email protected] Abstract In this case series, we describe four cases in which the use of gamma interferon release assays with purified protein derivative (PPD)[ncbi.nlm.nih.gov]

  • Toxoplasma Gondii

    KEYWORDS: Toxoplasma gondii ; acylation; cAMPdependent protein kinase A; cGMP‐dependent protein kinase G; egress[ncbi.nlm.nih.gov] In only one sample was T. gondii isolated by mouse inoculation but not detected by PCR.[ncbi.nlm.nih.gov] TgCDPK2, a member of the T. gondii calcium-dependent protein kinase family, was recently identified as an essential regulator for viable cyst development in T. gondii.[ncbi.nlm.nih.gov] KEYWORDS: Host-pathogen interaction; Protein-protein interaction; Tg14–3-3; Toxoplasma gondii; Yeast two-hybrid system[ncbi.nlm.nih.gov] This study was mainly focused on an estradiol regulatory factor-Hydroxysteroid dehydrogenase (HSD) gene in T. gondii.[ncbi.nlm.nih.gov] In higher Eukaryotes, the four-subunit chromosomal passenger complex (CPC) (Aurora kinase B (ARKB)/INCENP/Borealin/Survivin) promotes chromosome bi-orientation by detaching[ncbi.nlm.nih.gov] […] the nervous system tropism of T. gondii , and the phenomenon of huge cyst burdens developing in the mouse brain during chronic infection.[ncbi.nlm.nih.gov]

    Missing: beta1
  • Neuroepithelioma

    Furthermore, a cAMP-dependent protein kinase (PKA) inhibitor strongly blocked the action of cAMP analog, although it was not able to inhibit the same action of NGF.[ncbi.nlm.nih.gov] This fragment was subsequently used to clone both mouse and human full length cDNAs for this gene.[ncbi.nlm.nih.gov] All three receptors were also capable of stimulating c-Jun NH2-terminal kinases (JNK) and p38 MAPK.[ncbi.nlm.nih.gov] […] thrombocytopenia syndrome Bleeding diathesis due to a collagen receptor defect Bleeding diathesis due to glycoprotein VI deficiency Bleeding diathesis due to integrin alpha2-beta1[se-atlas.de] This motif is also present in other growth regulatory molecules including Bcr, Cdc24, Vav, Ras-Grf, Ect2, Ost, Tim and Tiam1, which have been implicated as regulators of small[ncbi.nlm.nih.gov] The presence of at least Galphas, Galphai3, and Galphai2 subunits was indicated.[ncbi.nlm.nih.gov] Min Wang, Yuntao Xie, Leonard Girnita, Gunnar Nilsson, Anica Dricu, Johan Wejde and Olle Larsson , Regulatory Role of Mevalonate and N-Linked Glycosylation in Proliferation[doi.org]

  • Rhubarb

    Furthermore, RTE suppressed the production of cyclic monophosphate- (cAMP-) dependent protein kinase A catalytic subunits α (PKA C-α) and phosphorylated cAMP response element-binding[ncbi.nlm.nih.gov] kinase (MAPK) signaling cascades.[ncbi.nlm.nih.gov] The differences of TGF-beta1, IL-6, RILT, and PF between the two groups were analysed.[ncbi.nlm.nih.gov] Furthermore, we found that rhubarb suppressed the p-ser(9) GSK-3-β protein level to inactivate Wnt signalling and reduce β-catenin protein level.[ncbi.nlm.nih.gov] This information enlarges the current regulatory knowledge regarding the classification of these important flavor compounds as "natural" on the basis of their enantiomeric[ncbi.nlm.nih.gov] Furthermore, RTE suppressed the production of cyclic monophosphate- (cAMP-) dependent protein kinase A catalytic subunits α (PKA C-α) and phosphorylated cAMP response element-binding[ncbi.nlm.nih.gov] These capabilities are reported to act through tyrosine kinases, phosphoinositol 3-kinase (PI3K), protein kinase C (PKC), NF-kappa B (NF-kappaB), and mitogen-activated protein[ncbi.nlm.nih.gov]

    Missing: mouse
  • Nicotine Withdrawal

    In the brain of smoking individuals, calcium-dependent plasticity induced by non-invasive brain stimulation methods such as transcranial direct current stimulation (tDCS)[ncbi.nlm.nih.gov] Additionally, rodent behavioral models and transgenic mouse models have revealed that specific nicotinic acetylcholine receptor (nAChR) subunits, cellular components, and[ncbi.nlm.nih.gov] The calcium activated protein, calcium/calmodulin-dependent protein kinase IV (CaMKIV) phosphorylates the downstream transcription factor cyclic AMP response element binding[ncbi.nlm.nih.gov] We conclude that PCDH-α, -β and -γ gene cluster regulatory variation influences the severity of nicotine withdrawal.[ncbi.nlm.nih.gov] Particularly the α2, α5, and β4 subunits of the nicotinic acetylcholine receptor have critical roles in mediating the somatic manifestations of withdrawal.[ncbi.nlm.nih.gov] There are many receptor sub-types of the nAChR, but nicotine has a high affinity for the one in which the β2 subunit is coupled with α4 or another subunit.[thefix.com] Environment and Human Factors, Ardeystraße 67, 44139, Dortmund, Germany. [email protected] 6 Department of Neurology, University Medical Hospital Bergmannsheil, Bürkle de la Camp-Platz[ncbi.nlm.nih.gov]

    Missing: beta1
  • Peptostreptococcus

    The phosphorylation of macrophage kinases, including cAMP-dependent protein-serine kinase (PKA) catalytic subunit beta, G protein-coupled receptor-serine kinase 2, mitogen-activated[ncbi.nlm.nih.gov] […] single injection of the organisms ( P P P. micros was injected into mouse with the culture filtrate of P. intermedia .[ingentaconnect.com] One per cent SDS and M urea both extracted a major 78 kDa protein from all strains of P anaerobius.[ncbi.nlm.nih.gov] Total cholesterol levels were significantly increased in colon cell lines exposed to P anaerobius via activation of sterol regulatory element-binding protein 2.[ncbi.nlm.nih.gov] Related enzymatic activities, such as serine dehydratase, pyruvate formate-lyase, formate dehydrogenase, pyruvate oxidoreductase, phosphate acetyltransferase, and acetate kinase[ncbi.nlm.nih.gov] "Protein L" Related Products Recombinant Peptostreptococcus magnus Protein L protein, Biotin/His-tagged Cat.No.: Protein L-8141P Product Overview: Recombinant Peptostreptococcus[creativebiomart.net] A rapid protein purification protocol is described.[ncbi.nlm.nih.gov]

    Missing: beta1

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