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64 Possible Causes for Bicarbonate Decreased, Cognitive Defect, Confusion

  • Acidosis

    Labs: General Arterial Blood Gas Arterial pH decreased Serum bicarbonate decreased PaCO2 decreased PaCO2 drops 1.2 mmHg per 1 meq/L bicarbonate fall Calculated PaCO2 1.5 x[fpnotebook.com] Respiratory acidosis:Presenting signs can include lethargy or fatigue, shortness of breath, confusion and sleepiness.[symptoma.com] A persistent decrease in the rate of renal bicarbonate reabsorption that maintains the decreased plasma bicarbonate level. c.[slideshare.net]

  • Acute Alcohol Intoxication

    […] in serum bicarbonate concentration.[cjasn.asnjournals.org] Alcohol, Vitamin B1 – Thiamine Deficiency and Brain Damage Acute alcohol intoxication will typically produce unsteadiness, slurring of speech and mild confusion.[stewartnutrition.co.uk] Confusion If a man consumes more than five drinks or a woman more than 4 drinks in an hour, they’ll enter the next stage of intoxication: confusion.[healthline.com]

  • Hyponatremia

    15% to 20%, hyperchloremic acidosis, decreased serum bicarbonate level, potassium abnormalities (type dependent) Correct acidosis, sodium bicarbonate Salt-wasting nephropathies[aafp.org] Moderate - personality change, muscle cramps and weakness, confusion, ataxia. Severe - drowsiness.[patient.info] A 41 year old Jordanian gentleman known case of osteogenesis imperfecta presented with vomiting, decreased oral intake followed by confusion.[ncbi.nlm.nih.gov]

  • Chronic Kidney Insufficiency

    Neutralization of dietary acid with sodium bicarbonate decreases kidney injury and slows kidney function decline, but sodium bicarbonate (baking soda) has sodium; so, doctors[nutritionfacts.org] Before then, conflicting classifications had created a state of confusion as to how many Americans were afflicted with this progressive, life-threatening condition.[lifeextension.com] The waste buildup can make you sick and you may have these symptoms: swelling of the ankles, face or belly, vomiting, loss of appetite, fatigue, weakness, confusion and headaches[heart.org]

  • Hypercapnia

    The increase in PaCO 2 , in turn, decreases the bicarbonate (HCO 3 – )/PaCO 2 ratio, thereby decreasing the pH.[emedicine.medscape.com] According to other sources, symptoms of mild hypercapnia might include headache, confusion and lethargy.[en.wikipedia.org] The renal system participates in acid-base regulation by increasing or decreasing levels of bicarbonate (HCO3-).[rtmagazine.com]

  • Drug-induced Hypoglycemia

    Drugs leading to loss of bicarbonate in the gastrointestinal (GI) tract or kidney 3. Drugs causing increased endogenous acid production 4.[f1000research.com] These similarities can lead to confusion in the diagnosis of hypoglycemia versus AMS, particularly for diabetics ascending to altitude.[ncbi.nlm.nih.gov] Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM. Diabetes 1994;43:1426–34. Fanelli C, Pampanelli S, Epifano L, et al.[guidelines.diabetes.ca]

  • Heat Stroke

    Alkalinizing agents: These medicines, such as potassium and sodium bicarbonate, decrease the amount of acid in your blood and urine. This helps prevent organ damage.[drugs.com] Heat stroke is a life-threatening condition which is characterised by nausea, vomiting, confusion, disorientation and coma.[ncbi.nlm.nih.gov] A 32-year-old male presented to a San Antonio hospital in March 2014 with progressive confusion, nausea, nonbloody emesis, and ataxia.[ncbi.nlm.nih.gov]

  • Diabetic Ketotic Coma

    Indeed this is much higher then expected given the relatively modest decrease in bicarbonate.[anaesthesiamcq.com] […] non-ketotic coma is a metabolic emergency usually seen in elderly non-insulin dependent diabetics, characterized by severe hyperglycaemia, volume depletion, altered consciousness, confusion[ncbi.nlm.nih.gov] Many clinicians have observed worsening of acidemia, as evidenced by decreased serum bicarbonate concentration, after aggressive resuscitation with normal saline.[ahcmedia.com]

  • Hypernatremia

    15% to 20%, hyperchloremic acidosis, decreased serum bicarbonate level, potassium abnormalities (type dependent) Correct acidosis, sodium bicarbonate Salt-wasting nephropathies[aafp.org] Confusion, neuromuscular excitability, hyperreflexia, seizures, or coma may result.[merckmanuals.com] Lastly, rarer causes of hypernatremia in the elderly population include sodium overload from iatrogenic excessive administration of sodium bicarbonate or hypertonic saline[dovepress.com]

  • High Altitude Cerebral Edema

    It is a carbonic anhydrase inhibitor that causes a bicarbonate diuresis and metabolic acidosis.[lifeinthefastlane.com] Symptoms commonly are headache, ataxia, and confusion progressing to stupor and coma.[ncbi.nlm.nih.gov] It is not to be confused with high altitude pulmonary oedema (HAPE), where fluid l eakage affects the air sacs of the lungs.[firstaidtrainingclasses.ca]

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