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14 Possible Causes for Bicarbonate Decreased, Cognitive Defect, Generalized Motor Seizure

  • Hyponatremia

    […] phenomena. [15] In a complex partial seizure a person may appear confused or dazed and can not respond to questions or direction.[en.wikipedia.org] 15% to 20%, hyperchloremic acidosis, decreased serum bicarbonate level, potassium abnormalities (type dependent) Correct acidosis, sodium bicarbonate Salt-wasting nephropathies[aafp.org] Focal seizure may become generalized. [15] Jerking activity may start in a specific muscle group and spread to surrounding muscle groups—known as a Jacksonian march. [16][en.wikipedia.org]

  • Chronic Kidney Insufficiency

    Neutralization of dietary acid with sodium bicarbonate decreases kidney injury and slows kidney function decline, but sodium bicarbonate (baking soda) has sodium; so, doctors[nutritionfacts.org] Moderate metabolic acidosis (plasma bicarbonate content 15 to 20 mmol/L) is characteristic.[merckmanuals.com] Potassium may be high and bicarbonate levels may be low if you have CKD. There may also be an increase of acid in the blood.[healthline.com]

  • Drug-induced Hypoglycemia

    Drugs leading to loss of bicarbonate in the gastrointestinal (GI) tract or kidney 3. Drugs causing increased endogenous acid production 4.[f1000research.com] Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM. Diabetes 1994;43:1426–34. Fanelli C, Pampanelli S, Epifano L, et al.[guidelines.diabetes.ca] Drugs that decrease renal acid excretion Some medications cannot be placed into one single category, as they possess multiple mechanisms that can cause metabolic acidosis.[f1000research.com]

  • Heat Stroke

    Alkalinizing agents: These medicines, such as potassium and sodium bicarbonate, decrease the amount of acid in your blood and urine. This helps prevent organ damage.[drugs.com]

  • Hypernatremia

    15% to 20%, hyperchloremic acidosis, decreased serum bicarbonate level, potassium abnormalities (type dependent) Correct acidosis, sodium bicarbonate Salt-wasting nephropathies[aafp.org] Lastly, rarer causes of hypernatremia in the elderly population include sodium overload from iatrogenic excessive administration of sodium bicarbonate or hypertonic saline[dovepress.com] […] mannitol use Correct glucose level, stop mannitol use Renal tubular acidosis Urinary osmolar gap, increased urinary pH, urinary sodium 25 mEq per L, fractional excretion of bicarbonate[aafp.org]

  • Acute Renal Failure

    […] buildup of potassium Sodium bicarbonate is used to decrease acid buildup Acute Kidney Failure Follow-up The doctor will arrange follow-up visits as needed for the underlying[emedicinehealth.com] The individual's ability to live with multisystem diseases, cope with ensuing problems, and care for himself are markedly diminished. failure of artificial pacemaker A defect[medical-dictionary.thefreedictionary.com] Sodium bicarbonate hydration improves urinary alkalinization, as opposed to normal saline hydration, which presumably works by decreasing the concentration of contrast media[circ.ahajournals.org]

  • Hypocalcemia

    Types are generalized tonic-clonic, focal motor, and less frequently, atypical absence and akinetic seizures. 3,40,41 They occur in 20-25% of patients presenting with hypocalcemia[epilepsy.com] RESULTS: Among controls, hypocalcemia elicited a major rise in intact PTH (iPTH) levels 4 minutes after bicarbonate infusion.[ncbi.nlm.nih.gov] Cognitive defects such as mental retardation and memory impairment have been encountered.[web.archive.org]

  • Diabetic Ketotic Coma

    In some patients, focal neurologic signs (hemiparesis, hemianopsia) and seizures (partial motor seizures more common than generalized) may be the dominant clinical features[clinicaladvisor.com] Indeed this is much higher then expected given the relatively modest decrease in bicarbonate.[anaesthesiamcq.com] In some patients, focal neurological signs (hemiparesis, hemianopsia) and seizures (partial motor seizures more common than generalized) may be the dominant clinical features[spectrum.diabetesjournals.org]

  • Kearns-Sayre Syndrome

    Decreased serum level of sodium, chloride, bicarbonate, calcium, low T4 and TSH were seen while serum level of potassium was persistent mild elevated, glucose: 12 mmol/l;[ispub.com] (ataxia) Impaired cognitive function Diabetes Seizures (infrequent) Several endocrine disorders can be associated with KSS.[blouw.moneomed.com] Ptosis, muscle weakness and moderate cognitive deficits are usual in patients with KSS.[em-consulte.com]

  • Theophylline

    Over a 36-hour period, insulin was progressively decreased and finally stopped because of the rapid fall and normalization of blood glucose concentration.[ncbi.nlm.nih.gov] The estimated background risk of major birth defects and miscarriage for the indicated populations are unknown.[rxlist.com] Incidence of CIN was significantly less frequent with bicarbonate compared to sodium hydration (1/74 [1.4%] vs 7/78 [9.0%]; P   0.035).[ncbi.nlm.nih.gov]

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