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29 Possible Causes for Bicarbonate Decreased, Cognitive Defect, Leukocytes Increased

  • Acidosis

    Labs: General Arterial Blood Gas Arterial pH decreased Serum bicarbonate decreased PaCO2 decreased PaCO2 drops 1.2 mmHg per 1 meq/L bicarbonate fall Calculated PaCO2 1.5 x[fpnotebook.com] […] production of lactate caused by sustained increased inflammatory stimuli (see below).[emedicine.medscape.com] A persistent decrease in the rate of renal bicarbonate reabsorption that maintains the decreased plasma bicarbonate level. c.[slideshare.net]

  • Chronic Kidney Insufficiency

    Neutralization of dietary acid with sodium bicarbonate decreases kidney injury and slows kidney function decline, but sodium bicarbonate (baking soda) has sodium; so, doctors[nutritionfacts.org] Simultaneously, thrombocyte and leukocyte dysfunctions or deficiencies can arise.[lecturio.com] Moderate metabolic acidosis (plasma bicarbonate content 15 to 20 mmol/L) is characteristic.[merckmanuals.com]

  • Diabetic Ketotic Coma

    Indeed this is much higher then expected given the relatively modest decrease in bicarbonate.[anaesthesiamcq.com] Many clinicians have observed worsening of acidemia, as evidenced by decreased serum bicarbonate concentration, after aggressive resuscitation with normal saline.[ahcmedia.com] Moreover, several deleterious effects of bicarbonate therapy have been reported, such as increased risk of hypokalemia, decreased tissue oxygen uptake, and cerebral edema.[clinicaladvisor.com]

  • Heat Stroke

    Alkalinizing agents: These medicines, such as potassium and sodium bicarbonate, decrease the amount of acid in your blood and urine. This helps prevent organ damage.[drugs.com]

  • Drug-induced Hypoglycemia

    Drugs leading to loss of bicarbonate in the gastrointestinal (GI) tract or kidney 3. Drugs causing increased endogenous acid production 4.[f1000research.com] Pseudohypoglycemia occurs when processing of blood specimens in untreated test tubes is delayed and cells, such as RBCs and leukocytes (especially if increased, as in leukemia[merckmanuals.com] Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM. Diabetes 1994;43:1426–34. Fanelli C, Pampanelli S, Epifano L, et al.[guidelines.diabetes.ca]

  • Precursor-Cell Lymphoblastic Leukemia

    Allopurinol is a xanthine oxidase inhibitor that decreases the production of uric acid.[lecturio.com] The most common side-effects are feeling sick (nausea), loss of hair, and an increased risk of infection (as the normal white blood cells (leukocytes) are affected by treatment[patient.info] defects Patient Education Ensure that the patient's parents and guardians understand that ALL usually does not have a known cause, that accurate stratification helps guide[emedicine.medscape.com]

  • High Altitude Cerebral Edema

    It is a carbonic anhydrase inhibitor that causes a bicarbonate diuresis and metabolic acidosis.[lifeinthefastlane.com] The high leukocyte count in AMS could be attributed to the generalized inflammatory process that has been identified with increased inflammatory markers such as leukotrienes[lungindia.com] It increases the hypoxic ventilatory response, decreases CSF production and may also have effects on the perripheral chemoreceptors. It is usually well tolerated.[lifeinthefastlane.com]

  • Pregnancy

    The renal system compensates by increasing excretion of bicarbonate.[emedicine.medscape.com] During treatment the leukocyte count decreased remarkably, and the patient developed lymphopenia together with a paradoxical increase in her blood platelet count.[ncbi.nlm.nih.gov] Fetal alcohol syndrome is a leading cause of cognitive disabilities in children.[medicinenet.com]

  • Diabetes Mellitus

    Bicarbonate therapy The use of bicarbonate in DKA is controversial ( 62 ) because most experts believe that during the treatment, as ketone bodies decrease there will be adequate[web.archive.org] She possessed F1DM-susceptible Human Leukocyte Antigen-DR4. A fluorescence activated cell sorting analysis showed an altered T-cell population.[ncbi.nlm.nih.gov] 'cognition', 'mixed depression and dementia', 'presenile dementia', 'frontotemporal dementia', 'dementia' or 'multiinfarct dementia', 'senile dementia', 'cognitive defect'[doi.org]

  • Acute Renal Failure

    […] buildup of potassium Sodium bicarbonate is used to decrease acid buildup Acute Kidney Failure Follow-up The doctor will arrange follow-up visits as needed for the underlying[emedicinehealth.com] […] in serum creatinine by 0.3 mg/dL within 48 hours blood urea nitrogen (BUN):creatinine ratio urinalysis dipstick to assess for protein, glucose, leukocyte esterase, hemoglobin[step2.medbullets.com] The individual's ability to live with multisystem diseases, cope with ensuing problems, and care for himself are markedly diminished. failure of artificial pacemaker A defect[medical-dictionary.thefreedictionary.com]

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