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217 Possible Causes for Bicarbonate Decreased, Dysphagia

  • Cystinosis

    Slow eating and dysphagia are common. Heterozygotes may have elevated levels of free cystine in leukocytes.[disorders.eyes.arizona.edu] A subset of patients may also suffer from dysphagia, malnutrition and frequent aspiration. These patients are usually treated with an implantation of a gastrostomy tube.[symptoma.com]

  • Gastroesophageal Reflux Disease

    Cigarette smoking can reduce the LES pressure[ 117 – 119 ] and decrease salivary bicarbonate secretion, thus reducing the physiological neutralizing effect of saliva on intraesophageal[doi.org] Outcomes selected were recurrent or persistent postoperative dysphagia and an abnormal 24-hour pH test result.[ncbi.nlm.nih.gov] […] secretion of bicarbonate by esophageal submucosal glands and attenuated ability of the cells lining the esophagus to resist acid injury. 1 Diagnosis CLINICAL PRESENTATION[aafp.org]

  • Peptic Esophagitis

    […] may show a decreased salivary bicarbonate response to acid perfusion challenge to the distal esophagus.[nature.com] Typical symptoms include pyrosis, dysphagia and regurgitation.[symptoma.com] Dysphagia, requiring repeat dilation, occurred in two patients after operation.[ncbi.nlm.nih.gov]

  • Gastropathy

    Thus, inhibition of COX by NSAIDs reduces prostaglandin synthesis, thereby diminishing mucosal blood flow and decreasing mucus and bicarbonate secretion.[emedicine.medscape.com] […] gastritis and gastroenteritis may affect all age groups and present with failure to thrive (in children), abdominal pain, irritability, gastric dysmotility, vomiting, diarrhoea, dysphagia[cmej.org.za] Decreased blood flow and decreased mucosa decrease the healing ability and leave the stomach more exposed to injury from pepsin and gastric acid.[physio-pedia.com]

  • Esophageal Ulcer

    In turn, less prostaglandin E was available to promote bicarbonate and mucus secretion, which are protective of the gastrointestinal mucosa [ 12 ].[bmcpediatr.biomedcentral.com] Esophageal involvement of multiple myeloma should be kept in mind in patients presenting with dysphagia.[ncbi.nlm.nih.gov] Odynophagia, retrosternal chest pain and dysphagia were the usual presenting symptoms. The typical endoscopic finding was that of discrete ulcers in the mid-esophagus.[ncbi.nlm.nih.gov]

  • Glycogen Storage Disease Type 2

    Progressive respiratory insufficiency Chronic CO 2 retention (elevated arterial pCO 2 and serum bicarbonate concentration) and hypoxemia (decreased arterial pO 2 and oxygen[dx.doi.org] Oropharyngeal dysphagia in infants and children with infantile Pompe disease. Dysphagia. 2009 Sep 10. [Medline]. Musumeci O, la Marca G, Spada M, et al.[emedicine.medscape.com] Oropharyngeal dysphagia in infants and children with infantile pompe disease.[ncbi.nlm.nih.gov]

  • Diaphragmatic Hernia

    Hypoxia (oxygen saturation Treatment includes increased oxygen delivery (100% oxygen), decreasing the PCO2 and treating acidosis with sodium bicarbonate (0.5-1 mEq/kg) for[clinicalpainadvisor.com] Granderath FA, Schweiger UM, Kamolz T, Pointner R (2005) Dysphagia after laparoscopic antireflux surgery: a problem of hiatal closure more than a problem of the wrap.[link.springer.com]

  • Lye Poisoning

    Administer Sodium Bicarbonate IV (check local protocol).[medictests.com] Symptoms and Signs Initial symptoms of caustic ingestion include drooling and dysphagia.[merckmanuals.com] Oesophageal and gastrointestinal burns Gastrointestinal signs and symptoms such as vomiting, haematemesis, increased salivation, ulcerative mucosal burns or dysphagia may[academic.oup.com]

  • Presbyesophagus

    Gum, especially bicarbonate gum, has been shown to increase salivary bicarbonate and prevent reflux.[ucdvoice.org] Among the dysphagia, esophageal dysphagia occurs more commonly in the aged.[freepaper.me] Signs and Symptoms Dysphagia will classically present as either: difficulty in initiating a swallow - oropharyngeal dysphagia the sensation that foods or liquids are being[southwest.devonformularyguidance.nhs.uk]

  • Respiratory Alkalosis

    Measurement of the serum bicarbonate permits definitive diagnosis: acute respiratory alkalosis: serum bicarbonate decreases by 2 mM for every 10 mmHg (or 1.33kPa) decrease[gpnotebook.co.uk] Often, UVFP is associated with dysphagia, specifically with liquids, because the resultant glottal incompetence can lead to aspiration.[emedicine.medscape.com] RESULTS: For each decrease of 1 mm Hg (0.13 kPa) in the PaCO2, the plasma bicarbonate concentration decreased by 0.41 mmol per liter in the subjects who started with a normal[ncbi.nlm.nih.gov]

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