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121 Possible Causes for Bicarbonate Decreased, Failure to Thrive, Potassium Decreased

  • Cystinosis

    Acidosis-affected patients are often administered with sodium citrate and supplements of phosphorus as well as potassium.[patienthelp.org] Cystinosis is the major cause of inherited Fanconi syndrome, and should be suspected in young children with a failure to thrive and with signs of renal proximal tubular damage[ncbi.nlm.nih.gov] The history of muscle weakness, failure to thrive, polydipsia, and polyuria prompted subsequent clinical and laboratory evaluations, leading to the correct diagnosis of cystinosis[ncbi.nlm.nih.gov]

  • Renal Tubular Acidosis

    […] resorption Decrease in aldosterone secretion or activity Plasma bicarbonate (mEq/L or mmol/L) Frequently 15, occasionally 10 Usually 12–20 Usually 17 Plasma potassium Usually[msdmanuals.com] Levels of potassium are usually decreased in proximal RTA although they can be normal.[medfriendly.com] Clinical symptoms vary from mild acidosis, incidental detection of kidney stones or renal tract calcification to severe findings such as failure to thrive, severe metabolic[ncbi.nlm.nih.gov]

  • Proximal Renal Tubular Acidosis

    Increased alkalinity of proximal tubular cells would explain the low rate of bicarbonate reabsorption per liter glomerular filtration and the decreased rate of ammonium excretion[ncbi.nlm.nih.gov] This, in turn, causes inadequate secretion of protons and potassium, with decreased trapping and excretion of ammonium and decreased excretion of potassium.[emedicine.medscape.com] We think that low doses of alkali are useful in the transient form of proximal renal tubular acidosis to prevent bone lesions and failure to thrive.[ncbi.nlm.nih.gov]

  • Distal Renal Tubular Acidosis

    The nephrons, when bathed in an acidic solution, demonstrated an acid-induced adaptive decrease in bicarbonate secretion.[derangedphysiology.com] In five patients, impaired potassium excretion was associated with decreased ammonium excretion, a urinary pH below 5.5 (5.18 0.07, mean S.E.M.), and aldosterone deficiency[nejm.org] We suggest that RTA be considered a diagnostic possibility in all children with failure to thrive and nephrocalcinosis.[ncbi.nlm.nih.gov]

  • Metabolic Alkalosis

    It is the result of an increase in bicarbonate production, a decrease in bicarbonate excretion, or a loss of hydrogen ions.[ncbi.nlm.nih.gov] Serum chloride: Decreased, less than 98 mEq/L, disproportionately to serum sodium decreases (if alkalosis is hypochloremia). Serum potassium: Decreased.[nurseslabs.com] Abstract A 7-month-old infant with failure to thrive and recurrent episodes of vomiting and metabolic alkalosis was evaluated.[pediatrics.aappublications.org]

  • Hyponatremia

    15% to 20%, hyperchloremic acidosis, decreased serum bicarbonate level, potassium abnormalities (type dependent) Correct acidosis, sodium bicarbonate Salt-wasting nephropathies[aafp.org] Swollen brain cells react to hyponatremic conditions by decreasing their volume over approximately 48 h by the extrusion of potassium, sodium, chloride, and organic osmolytes[doi.org] Hyponatremia should be suspected in children with Prader-Willi syndrome, especially in infants with severe failure to thrive.[ncbi.nlm.nih.gov]

  • Islet Cell Tumor

    Decreased pancreatic secretion of enzymes and bicarbonate accounts for the diarrhea and steatorrhea.[es.oncolink.org] Twenty-five of 47 (53%) patients had decreased serum potassium levels.[ncbi.nlm.nih.gov] […] in the blood, which can cause an irregular heartbeat, muscle cramping and weakness, and decreased reflexes Too little acid in the stomach, which can cause digestive problems[cancer.net]

  • Diabetes Mellitus

    Bicarbonate therapy The use of bicarbonate in DKA is controversial ( 62 ) because most experts believe that during the treatment, as ketone bodies decrease there will be adequate[web.archive.org] Hyperglycemia, failure to thrive and, in some cases, dehydration occur after birth.[ncbi.nlm.nih.gov] Signs and symptoms directly associated with CD These include malabsorption and malnutrition, vitamin deficiencies, iron deficiency anemia, failure to thrive, short stature[dx.doi.org]

  • Acidosis

    Labs: General Arterial Blood Gas Arterial pH decreased Serum bicarbonate decreased PaCO2 decreased PaCO2 drops 1.2 mmHg per 1 meq/L bicarbonate fall Calculated PaCO2 1.5 x[fpnotebook.com] Some small effects occur on calcium and potassium levels. Acidosis decreases binding of calcium to albumin and tends to increase serum ionized calcium levels.[en.wikipedia.org] Failure to thrive, rickets, stunting of growth (seen in children) and osteomalacia or osteopenia (seen in adults) are a result of urinary calcium wastage and a loss of calcium[orpha.net]

  • Hypoaldosteronism

    […] plasma bicarbonates level (HCO3-: 16 mmol/l; N: 27-30).[ncbi.nlm.nih.gov] […] aldosterone synthesis, decreased potassium secretion in collecting duct Digoxin at toxic levels Decreases sodium-potassium ATPase activity Fluoride toxicity Decreases aldosterone[aafp.org] We report a 4 month old female infant who presented with failure to thrive, persistent hyponatremia and hyperkalemia.[ncbi.nlm.nih.gov]

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