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140 Possible Causes for Bicarbonate Decreased, Glycosuria

  • Cystinosis

    The de Toni-Fanconi syndrome* is a clinical constellation characterized by resistant rickets, acidosis, glycosuria, hyperamino-aciduria, and organic aciduria.[doi.org] All had nephropathic infantile-type cystinosis with evidence of proximal tubulopathy, with glycosuria and renal phosphate wasting.[ncbi.nlm.nih.gov] Diagnostic methods The diagnosis is based on blood and urine analysis showing features of Fanconi syndrome (metabolic acidosis, hypokalemia, hyperaminoaciduria, glycosuria[orpha.net]

  • Pregnancy

    The renal system compensates by increasing excretion of bicarbonate.[emedicine.medscape.com] […] early adulthood, cigarette smoking, previous macrosomic infant, previous stillbirth, previous major malformation, excess maternal weight gain in current pregnancy, recurrent glycosuria[doi.org] Expiratory reserve volume (ERV) decreases 15%. Residual volume decreases. Vital capacity does not change. Inspiratory capacity increases 5%.[emedicine.medscape.com]

  • Renal Tubular Acidosis

    […] resorption Decrease in aldosterone secretion or activity Plasma bicarbonate (mEq/L or mmol/L) Frequently 15, occasionally 10 Usually 12–20 Usually 17 Plasma potassium Usually[msdmanuals.com] The blood salicylate level was undetectable, and a urinalysis showed glycosuria, proteinuria and elevated beta-2 microglobulin and n-acetyl glucosamine levels, with a normal[ncbi.nlm.nih.gov] He was also found to have hyperchloraemic metabolic acidosis with hypokalaemia, hypophosphataemia, phosphaturia and glycosuria, which favoured a diagnosis of proximal renal[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    Bicarbonate therapy The use of bicarbonate in DKA is controversial ( 62 ) because most experts believe that during the treatment, as ketone bodies decrease there will be adequate[web.archive.org] He attributed the decrease in urinary sugar to a ‘temporary toxic renal effect’ (he had been expecting a compensating increase in glycosuria).[dx.doi.org] Subsequently, hyperglycemia and glycosuria, but not ketonuria, occured.[pediatrics.aappublications.org]

  • Proximal Renal Tubular Acidosis

    Increased alkalinity of proximal tubular cells would explain the low rate of bicarbonate reabsorption per liter glomerular filtration and the decreased rate of ammonium excretion[ncbi.nlm.nih.gov] […] a solitary defect, but is usually associated with a more generalised dysfunction of the proximal tubular cells called Fanconi syndrome where there is also phosphaturia, glycosuria[en.wikipedia.org] The normal bicarbonate resorption threshold (26-27 mmol/L) is decreased to something around 20mmol/L.[derangedphysiology.com]

  • Renal Tubular Dysfunction

    A decrease in proximal tubular bicarbonate resorptive capacity results in proximal (type 2) RTA.[clinicaladvisor.com] Our patients (5 women and 2 men) developed renal tubular dysfunction, with hypophosphatemia, normoglycemic glycosuria, proteinuria, and decrease of creatinine clearance.[ncbi.nlm.nih.gov] Estimated glomerular filtration rate (eGFR) and markers of tubular damage to assess tubular dysfunction (fractional excretion of phosphate and uric acid, glycosuria, and proteinuria[ncbi.nlm.nih.gov]

  • Fanconi Renotubular Syndrome

    The amount of filtered bicarbonate decreases until a new threshold is established and all filtered bicarbonate is then again reabsorbed, resulting in a persistent metabolic[ncbi.nlm.nih.gov] Defects in proximal tubular function can be isolated (e.g. isolated renal glycosuria, aminoacidurias, or hypophosphataemic rickets) or generalized.[oxfordmedicine.com] Not to be mistaken for Fanconi syndrome, proximal renal tubular acidosis (RTA), also known as Type 2 RTA, is characterized by a decreased rate of bicarbonate reabsorption[cureus.com]

  • Adult Fanconi Syndrome

    ] Decreased serum calcium and increased parathyroid hormone levels associated with Vitamin D deficiency probably reduce the bicarbonate reabsorption at the proximal tubules[sjkdt.org] Defects in proximal tubular function can be isolated (e.g. isolated renal glycosuria, aminoacidurias, or hypophosphataemic rickets) or generalized.[oxfordmedicine.com] Loss of these compounds can cause problems such as · growth failure, · decreased bone mineralization ( rickets ), · and abnormal bone mineralization (osteomalacia). · Type[sinoemedicalassociation.org]

  • Acidosis

    Labs: General Arterial Blood Gas Arterial pH decreased Serum bicarbonate decreased PaCO2 decreased PaCO2 drops 1.2 mmHg per 1 meq/L bicarbonate fall Calculated PaCO2 1.5 x[fpnotebook.com] Specific amino aciduria as seen in isolated cystinuria, glucose loss in isolated glycosuria, and isolated phosphaturia do not constitute Fanconi's syndrome.[bestpractice.bmj.com] A persistent decrease in the rate of renal bicarbonate reabsorption that maintains the decreased plasma bicarbonate level. c.[slideshare.net]

  • Metabolic Acidosis

    Thus, correcting acidosis in CKD with bicarbonate decreases IL-10 secretion. Its significance needs to be further investigated. Copyright 2015 Elsevier Masson SAS.[ncbi.nlm.nih.gov] The blood salicylate level was undetectable, and a urinalysis showed glycosuria, proteinuria and elevated beta-2 microglobulin and n-acetyl glucosamine levels, with a normal[ncbi.nlm.nih.gov] Labs: General Arterial Blood Gas Arterial pH decreased Serum bicarbonate decreased PaCO2 decreased PaCO2 drops 1.2 mmHg per 1 meq/L bicarbonate fall Calculated PaCO2 1.5 x[fpnotebook.com]

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