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114 Possible Causes for Bicytopenia

  • Hypocupremia

    Copper deficiency usually presents with bicytopenia (neutropenia and anemia), but severe pancytopenia has been observed in some cases, especially those patients on TPN.[]

  • Nephritis

    HPS could be diagnosed with the presence of six criteria: fever, splenomegaly, bicytopenia, high ferritin, hypertriglyceridemia, and high levels of soluble CD25.[]

  • Griscelli Syndrome, Type 2

    Figure 1: Note the silvery discoloration of the scalp hair and the eyebrows Click here to view Investigation revealed bicytopenia, with hemoglobin of 5.8 gm/dl and platelets[] […] mL) and the triglycerides was 279 mg/dL (normal values: In view of sudden onset of high grade fever with no foci of infection with lymphadenopathy, hepatosplenomegaly and bicytopenia[]

  • Autosomal Recessive Dyskeratosis Congenita Type 5

    , hypothyroidism, dry skin, dystrophic nails (Figure 1A), skin pigmentations, tooth abnormality, scoliosis, omnibus sign and saddle nose (Figure 1B, C), lung disease and bicytopenia[]

  • Refractory Anemia with Excess Blasts

    Diagnosis Comment: There is leukocytosis and bicytopenia (normocytic anemia and thrombocytopenia).[] Refractory cytopenia with multilineage dysplasia is characterized by bicytopenia or pancytopenia.[] […] count No or rare blasts ( Normal to increased megakaryocytes with hypolobated nuclei Isolated del(5q) cytogenetic abnormality No Auer rods MDS, myelodysplastic syndrome. * Bicytopenia[]

  • Familial Hemophagocytic Lymphohistiocytosis

    Hemogram revealed bicytopenia and bone marrow aspirate showed hemophagocytosis.[] […] guidelines of the Histiocyte Society, diagnosis of Hemophagocytic Lympho-histiocytosis (HLH) requires fulfillment of 5 out of 8 criteria – prolonged fever, splenomegaly, bicytopenia[] As for bicytopenia, only the platelet count was low at admission; anemia developed later but was attributed to severe bleeding.[]

  • Bone Marrow Infiltration of Lymphoma

    A 64-year-old male initially presented with fatigue, splenomegaly, and bicytopenia. The bone marrow biopsy specimen revealed extensive infiltration with MCL.[] Sixty seven patients presented with pancytopenia/bicytopenia and bone marrow was done to detect the etiology ( Figure1 ). Table 1.[] […] lymphocytes, plasma cells in marrow and blasts, all of which are prognostic markers required in follow up of aplastic anemia. [ 28 ] Rarely, Hodgkin and NHL can present as pan or bicytopenia[]

  • Human Parvovirus B19

    These include cytopenias affecting the erythroid, megakaryoblastoid, myeloid and lymphoid lineages, as well as a variety of bicytopenias, pancytopenia, bone marrow necrosis[]

  • Amelogenesis Imperfecta

    No other family members presented amelogenesis imperfecta, bicytopenia, or platyspondyly.[] A complete blood count revealed bicytopenia (normocytic-normochromic anemia with thrombocytopenia).[] To the best of our knowledge, this is the first case report of a rare association of amelogenesis imperfecta, platyspondyly, and bicytopenia.[]

  • Diffuse Lymphoma

    He also met criteria for HLH with fever, bicytopenia, splenomegaly, ferritin level, and hypertriglyceridemia.[]

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