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20 Possible Causes for Bicytopenia, Bleeding Diathesis, Complete Blood Count Abnormal

  • Gaucher Disease

    Clinical manifestations include hepatosplenomegaly, thrombocytopenia, bone disease and a bleeding diathesis, frequently resulting in presentation to haematologists.[ncbi.nlm.nih.gov] [ncbi.nlm.nih.gov] Clinical manifestations include hepatosplenomegaly, thrombocytopenia, bone disease and a bleeding diathesis, frequently resulting in presentation to haematologists[symptoma.com]

  • Disseminated Intravascular Coagulation

    Bleeding diathesis must be corrected before surgery in order to prevent massive intraoperative bleeding.[kjim.org] Deficiency causes a clinical hemorrhagic diathesis.[medical-dictionary.thefreedictionary.com] Called also fibrin-stabilizing factor. disseminated [ dĭ-sem ĭ-nāt″ed ] scattered; distributed over a considerable area. disseminated intravascular coagulation (DIC) a bleeding[medical-dictionary.thefreedictionary.com]

  • Acute Myelocytic Leukemia

    It has not been treated except to relieve signs and symptoms such as fever, bleeding, or pain, and the following are true: The complete blood count is abnormal.[my.clevelandclinic.org] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[dx.doi.org] A general bleeding diathesis may be the result of thrombocytopenia. Patients may claim a propensity for epistaxis, bleeding gums, melena and hematochezia, and hematuria.[symptoma.com]

  • Promyelocytic Leukemia

    Initial testing may be indicated when a person has abnormal findings on a complete blood count (CBC) and/or blood smear such as an increased or decreased number of white blood[labtestsonline.org] The patient was treated with all-trans retinoic acid under a diagnosis of APL with improvement of the bicytopenia.[ncbi.nlm.nih.gov] Nevertheless, APL remains associated with a significant incidence of early death related to the characteristic bleeding diathesis.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] The indications included pancytopenia (all three cell lines), bicytopenia (two cell lines), and unicytopenia (one cell line).[bcmj.org] The cumulative incidence of bicytopenia or pancytopenia ( Figure 2 B) was similar in patients with classic and intermediate disease ( P .63).[bloodjournal.hematologylibrary.org]

  • Severe Aplastic Anemia

    A doctor can review your blood cell counts from a simple blood test called a complete blood count ( CBC ).[marrowforums.org] Patients suffering from anemia, thrombocytopenia and a bleeding diathesis should receive transfusions of the respective blood products.[symptoma.com] In our case, the patient presented with bleeding due to thrombocytopenia.[omicsonline.org]

  • Thrombocytopenia

    In a patient who is otherwise in his/her usual state of good health who has not taken a new medication, has thrombocytopenia and no other abnormality found in a complete blood[rarediseases.org] HIV post exposure prophylaxis induced bicytopenia: a case report. AIDS Res Ther . 2014; 11 :11. [ PubMed ] [ DOI ] 8. Visentin GP , Liu CY.[wjgnet.com] It is not indicative of a bleeding diathesis or platelet dysfunction.[patient.info]

  • Leukoerythroblastic Anemia

    Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] […] anemia, Sideroblastic anemia Blood tests Normocytic - Microcytic - Macrocytic - Normochromic - Hypochromic Other Methemoglobinemia Coagulation / platelets / coagulopathy / bleeding[wikidoc.org] Out of 70 cases 32 were reported as pancytopenia, 17 were microcytic hypochromic anemia, 10 normocytic normochromic blood picture, 3 dimorphic anemia ,2 bicytopenia, 2 CML[ispub.com]

  • Myelodysplasia

    WHEN TO SUSPECT MDS In many patients, MDS are asymptomatic and appear as an abnormality on a routine complete blood cell count (CBC) or as part of a workup for anemia.[mdedge.com] 2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] It may present as a bleeding diathesis with haemoptysis, haematuria or rectal bleeding.[patient.info]

  • Primary Myelofibrosis

    Primary myelofibrosis is diagnosed using the following procedures: Blood testing: Complete blood count (CBC) looking for abnormal amounts of red and white blood cells and[patientworthy.com] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] In general, laboratory analyses of blood samples are carried out in order to clarify the causes of persistent fatigue, recurrent infections, thrombosis or bleeding diathesis[symptoma.com]

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