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18 Possible Causes for Bicytopenia, Complete Blood Count Abnormal, Ferritin Increased

  • Gaucher Disease

    All forms of Gaucher disease affect males and females in equal numbers. Gaucher disease type 1 is the most common type, accounting for more than 90 percent of cases. Individuals with Gaucher disease type 1 usually exhibit symptoms during adolescence, but the age of onset ranges from childhood to adulthood. The[…][]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[] Deteriorating kidney function and persistent Fanconi syndrome were accompanied by a progressive increase in serum ferritin levels.[] The indications included pancytopenia (all three cell lines), bicytopenia (two cell lines), and unicytopenia (one cell line).[]

  • Pancytopenia

    The doctor will also do a complete blood count (CBC). This test measures the amount of red blood cells, white blood cells, and platelets in your blood.[] […] of bicytopenia and pancytopenia.[] But ferritin increased at 2791 μg/L, triglycerid increased at 3.1 mmol/L and lactate deshydrogenase increased at 1467 UI/L.[]

  • Autoimmune Hemolytic Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[] Inwards, How to Interpret and Pursue an Abnormal Complete Blood Cell Count in Adults, Mayo Clinic Proceedings, 80, 7, (923), (2005). D. Stahl and W.[]

  • Myelodysplasia

    WHEN TO SUSPECT MDS In many patients, MDS are asymptomatic and appear as an abnormality on a routine complete blood cell count (CBC) or as part of a workup for anemia.[] 2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[] The increase in cytosol ferritins is probably due to increased translation because of an increase in the free iron in the cytosol.[]

  • Leukoerythroblastic Anemia

    Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[] Increased: 2 people, 28.57% Red Blood Cell Sedimentation Rate Increased: 2 people, 28.57% Primary Hyperaldosteronism (too much aldosterone is produced by the adrenal glands[] RBC protoporphyrin increased BM- ringed sideroblasts Iron studies- Increased serum iron, increased iron saturation, increased ferritin- Decreased TIBC Anemia of Chronic Disease[]

  • Acquired Sideroblastic Anemia

    Complete blood count with differential will show variable severity of anemia, with usually normal leukocytes and platelets.[] RCMD-RS shows cytopenias (bicytopenia or pancytopenia) in the peripheral blood plus dysplasia in more than 10% of the cells in 2 or more myeloid lineages and no Auer rods.[] The precipitated serum proteins revealed an increased content of ferritin molecules only in the patients and not in control individuals, suggesting an increased supply of[]

  • Primary Myelofibrosis

    Primary myelofibrosis is diagnosed using the following procedures: Blood testing: Complete blood count (CBC) looking for abnormal amounts of red and white blood cells and[] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[] Red blood cell transfusion need at diagnosis adversely affects survival in primary myelofibrosis-increased serum ferritin or transfusion load does not.[]

  • Idiopathic Refractory Anemia

    The complete blood count results showed a severe thrombocytopenia and RBC abnormalities.[] My Response Distinguishing Cases of Immune-Mediated BM failure Diagnosing MDS is often challenging in patients with pancytopenia or bicytopenia who do not show definitive[] Serum iron, percentage saturation and ferritin are increased. The total iron-binding capacity of the cells is normal to decreased.[]

  • Dermatomyositis

    After corticosteroid and tacrolimus combination therapy was started, bicytopenia and elevated serum ferritin and transaminase emerged.[] However, his respiratory condition worsened as the serum ferritin level increased.[] Over the course of treatment, the anti-MDA5 antibody level continually decreased, while the serum ferritin level increased, suggesting that sequential measurements of the[]