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18 Possible Causes for Bicytopenia, Complete Blood Count Abnormal, Ferritin Increased

  • Gaucher Disease

    All forms of Gaucher disease affect males and females in equal numbers. Gaucher disease type 1 is the most common type, accounting for more than 90 percent of cases. Individuals with Gaucher disease type 1 usually exhibit symptoms during adolescence, but the age of onset ranges from childhood to adulthood. The[…][web.archive.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] Deteriorating kidney function and persistent Fanconi syndrome were accompanied by a progressive increase in serum ferritin levels.[ncbi.nlm.nih.gov] The indications included pancytopenia (all three cell lines), bicytopenia (two cell lines), and unicytopenia (one cell line).[bcmj.org]

  • Pancytopenia

    The doctor will also do a complete blood count (CBC). This test measures the amount of red blood cells, white blood cells, and platelets in your blood.[healthline.com] […] of bicytopenia and pancytopenia.[ijpmonline.org] But ferritin increased at 2791 μg/L, triglycerid increased at 3.1 mmol/L and lactate deshydrogenase increased at 1467 UI/L.[em-consulte.com]

  • Autoimmune Hemolytic Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] Inwards, How to Interpret and Pursue an Abnormal Complete Blood Cell Count in Adults, Mayo Clinic Proceedings, 80, 7, (923), (2005). D. Stahl and W.[doi.org]

  • Myelodysplasia

    WHEN TO SUSPECT MDS In many patients, MDS are asymptomatic and appear as an abnormality on a routine complete blood cell count (CBC) or as part of a workup for anemia.[mdedge.com] 2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] The increase in cytosol ferritins is probably due to increased translation because of an increase in the free iron in the cytosol.[doi.org]

  • Leukoerythroblastic Anemia

    Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] Increased: 2 people, 28.57% Red Blood Cell Sedimentation Rate Increased: 2 people, 28.57% Primary Hyperaldosteronism (too much aldosterone is produced by the adrenal glands[ehealthme.com] RBC protoporphyrin increased BM- ringed sideroblasts Iron studies- Increased serum iron, increased iron saturation, increased ferritin- Decreased TIBC Anemia of Chronic Disease[quizlet.com]

  • Acquired Sideroblastic Anemia

    Complete blood count with differential will show variable severity of anemia, with usually normal leukocytes and platelets.[clinicaladvisor.com] RCMD-RS shows cytopenias (bicytopenia or pancytopenia) in the peripheral blood plus dysplasia in more than 10% of the cells in 2 or more myeloid lineages and no Auer rods.[atlasgeneticsoncology.org] The precipitated serum proteins revealed an increased content of ferritin molecules only in the patients and not in control individuals, suggesting an increased supply of[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Primary myelofibrosis is diagnosed using the following procedures: Blood testing: Complete blood count (CBC) looking for abnormal amounts of red and white blood cells and[patientworthy.com] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] Red blood cell transfusion need at diagnosis adversely affects survival in primary myelofibrosis-increased serum ferritin or transfusion load does not.[doi.org]

  • Idiopathic Refractory Anemia

    The complete blood count results showed a severe thrombocytopenia and RBC abnormalities.[sysmex-europe.com] My Response Distinguishing Cases of Immune-Mediated BM failure Diagnosing MDS is often challenging in patients with pancytopenia or bicytopenia who do not show definitive[hematology.org] Serum iron, percentage saturation and ferritin are increased. The total iron-binding capacity of the cells is normal to decreased.[en.wikipedia.org]

  • Dermatomyositis

    After corticosteroid and tacrolimus combination therapy was started, bicytopenia and elevated serum ferritin and transaminase emerged.[ncbi.nlm.nih.gov] However, his respiratory condition worsened as the serum ferritin level increased.[ncbi.nlm.nih.gov] Over the course of treatment, the anti-MDA5 antibody level continually decreased, while the serum ferritin level increased, suggesting that sequential measurements of the[ncbi.nlm.nih.gov]