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28 Possible Causes for Bicytopenia, Complete Blood Count Abnormal, Generalized Lymphadenopathy

  • Gaucher Disease

    Protein-losing enteropathy due to massive mesenteric lymphadenopathy is a rare complication of Gaucher disease which is generally refractory to treatment with enzyme replacement[ncbi.nlm.nih.gov]

  • Follicular Lymphoma

    This patient was a 58 years old with generalized lymphadenopathy and Ann Arbor Stage III disease.[ncbi.nlm.nih.gov] A complete blood cell count (CBC) with differential should be obtained, including examination of the peripheral blood smear if the differential is abnormal.[emedicine.com] In addition, the presence of an autoimmune bicytopenia and a Klinefelter syndrome complicated the clinical context of the patient.[ncbi.nlm.nih.gov]

  • Acute Leukemia

    Some individuals with ALL and AML may develop localized or generalized lymphadenopathy, or even shortness of breath as a result of enlarged mediastinal nodes.[symptoma.com] A 1-year-old boy presented with abnormal complete blood count findings, and was found to have blasts and mild dysgranulopoiesis.[ncbi.nlm.nih.gov] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    On exam, he has bilateral submandibular lymphadenopathy and hepatosplenomegaly. CBC demonstrates decreased RBCs and mature WBCs.[step1.medbullets.com] It has not been treated except to relieve signs and symptoms such as fever, bleeding, or pain, and the following are true: The complete blood count is abnormal.[cancer.gov] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[bloodjournal.hematologylibrary.org]

  • Autoimmune Hemolytic Anemia

    lymphadenopathy, splenomegaly and mild hepatitis.[ncbi.nlm.nih.gov] Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org]

  • Castleman Disease

    CD can present with localized (unicentric CD or UCD) or generalized lymphadenopathy (multicentric CD or MCD).[hematology.org] Investigations showed bicytopenia, nephrotic range proteinuria with hypoalbuminemia, hypogammaglobulinemia, and features of hyaline-vascular type Castleman disease in a lymph[ncbi.nlm.nih.gov] Case Report: We present a case of a 63-year-old woman with multicentric CD who was admitted with weight loss, night sweat, fever, and generalized lymphadenopathy.[karger.com]

  • Systemic Mastocytosis

    On examination, splenomegaly occurs in 50% to 60% of patients, hepatomegaly in 50% to 70%, generalized lymphadenopathy in 40% and skin lesions are apparent in 60%.[healio.com] The doctor may want the patient to have a bone scan performed in adults or in children with an abnormal complete blood count (CBC).[medfriendly.com] Although the patient responded to the treatment, the relapse with splenomegaly and bicytopenia was observed after 10 months.[ncbi.nlm.nih.gov]

  • Disseminated Tuberculosis

    Physical examination reveals cough, splenomegaly, hepatomegaly, generalized lymphadenopathy and signs of multiorgan dysfunction. Genitourinary involvement is common.[symptoma.com] (Blood cultures reports and sensitivity tests in second and third week of admission at secondary hospital in appendix B) Her full blood count remained normal in follow-up[omicsonline.org] Patients and Methods 312 bone marrow aspirates from patients with the diagnosis of anaemia, severe granulocytopenia, thrombocytopenia, bicytopenia or pancytopenia, referred[tbonline.info]

  • Brucellosis

    One patient presented with generalized lymphadenopathy, and 1 patient presented with meningitis.[academic.oup.com] In this paper, we present a case of brucellosis with acute hepatitis and bicytopenia without anaemia.[ncbi.nlm.nih.gov] The diagnostic criteria include fever, hepatosplenomegaly, bicytopenia, high serum ferritin level, decreased natural killer cell activity, elevated soluble CD25 level, high[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Blood tests Chromosome analysis The diagnosis of CML is suspected when the results of a complete blood count show an abnormally high white blood cell count.[merck.com] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[doi.org] The diagnosis of chronic myelogenous leukemia is usually via a blood test called a complete blood count ( CBC ).[medicinenet.com]