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50 Possible Causes for Bicytopenia, Complete Blood Count Abnormal, Leukopenia

  • Gaucher Disease

    We report here the case of a young woman with hepatosplenomegaly, leukopenia, and thrombocytopenia.[ncbi.nlm.nih.gov] Spleen enlargement and bone marrow replacement cause anemia, thrombocytopenia, and leukopenia.[en.wikipedia.org] Splenectomy may be helpful for patients with anemia, leukopenia, or thrombocytopenia or when spleen size causes discomfort.[merckmanuals.com]

  • Pancytopenia

    The doctor will also do a complete blood count (CBC). This test measures the amount of red blood cells, white blood cells, and platelets in your blood.[healthline.com] In this study, we describe seven cases of severe thrombocytopenia, anemia and leukopenia (pancytopenia) from the same geographic locality and similar clinical presentation[ncbi.nlm.nih.gov] […] of bicytopenia and pancytopenia.[ijpmonline.org]

  • Myelodysplasia

    WHEN TO SUSPECT MDS In many patients, MDS are asymptomatic and appear as an abnormality on a routine complete blood cell count (CBC) or as part of a workup for anemia.[mdedge.com] Serum copper determination should be included in the work-up of patients with anemia and leukopenia of unclear etiology who have associated myeloneuropathy.[ncbi.nlm.nih.gov] 2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com]

  • Leukopenia

    A complete lack of one of the other granulocytic series is also abnormal and may have an impact on innate immunity, but is rarely a cause of a depressed total white blood[cancertherapyadvisor.com] The prognosis of leukopenia depends upon the cause, duration of leukopenia, as well as age of the patient.[symptoma.com] In February 2007 etanercept was suspended due to bicytopenia.[scielo.br]

  • Follicular Lymphoma

    A complete blood cell count (CBC) with differential should be obtained, including examination of the peripheral blood smear if the differential is abnormal.[emedicine.com] […] develops any systemic symptoms.Another set of symptoms which may occur in the later stages of the condition are those depicting dysfunction of the bone marrow such as anemia, leukopenia[symptoma.com] In addition, the presence of an autoimmune bicytopenia and a Klinefelter syndrome complicated the clinical context of the patient.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[merckmanuals.com]

  • Primary Myelofibrosis

    Primary myelofibrosis is diagnosed using the following procedures: Blood testing: Complete blood count (CBC) looking for abnormal amounts of red and white blood cells and[patientworthy.com] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com]

  • Promyelocytic Leukemia

    Initial testing may be indicated when a person has abnormal findings on a complete blood count (CBC) and/or blood smear such as an increased or decreased number of white blood[labtestsonline.org] In addition, microgranular APL often presents with an elevated or normal white blood cell count in contrast with the leukopenia seen in traditional APL.[ncbi.nlm.nih.gov] The patient was treated with all-trans retinoic acid under a diagnosis of APL with improvement of the bicytopenia.[ncbi.nlm.nih.gov]

  • Hypersplenism

    Unfortunately, these patients may become intolerant to this therapy when it is complicated by hypersplenism with leukopenia and/or thrombocytopenia.[ncbi.nlm.nih.gov] Baijal & Anshu Srivastava Hepatology International (2015) Bone marrow examination in Egyptian patients with bicytopenia/pancytopenia Somaia Mohammed Mousa Comparative Clinical[nature.com] A big spleen can cause anaemia, thrombocytopenia and/or leukopenia just by being that massive.[medicguide.blogspot.com]

  • Acute Myelocytic Leukemia

    It has not been treated except to relieve signs and symptoms such as fever, bleeding, or pain, and the following are true: The complete blood count is abnormal.[cancer.gov] The consolidation treatment was the same in both arms but caused significantly more leukopenia and thrombocytopenia in patients previously treated with HIDAC-3-7 induction[ncbi.nlm.nih.gov] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[bloodjournal.hematologylibrary.org]

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