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39 Possible Causes for Bicytopenia, Complete Blood Count Abnormal, Neutrophil Count Decreased

  • Gaucher Disease

    Lysosomal integral membrane protein type 2 (LIMP-2) is responsible for proper sorting and lysosomal targeting of glucocerebrosidase, the enzyme deficient in Gaucher disease (GD). Mutations in the gene for LIMP-2, SCARB2, are implicated in inherited forms of myoclonic epilepsy, and myoclonic epilepsy is part of the[…][ncbi.nlm.nih.gov]

  • Pancytopenia

    The doctor will also do a complete blood count (CBC). This test measures the amount of red blood cells, white blood cells, and platelets in your blood.[healthline.com] […] of bicytopenia and pancytopenia.[ijpmonline.org] Blood Film 1.RBC morphology ( size & shape) 2.WBC and RBC precursor 3.Platelets count & size 4.Abnormal increase or decrease granulation in Neutrophil 5.[slideshare.net]

  • Vitamin B12 Deficiency

    When you have an abnormal complete blood count (CBC) with a blood smear showing large red blood cells (macrocytosis) or abnormal (hypersegmented) neutrophils ; when you have[labtestsonline.org] Laboratory data revealed bicytopenia with macrocytic anemia and methylmalonic acid in the urine, consistent with vitamin B12 deficient anemia.[ncbi.nlm.nih.gov]

  • Leukoerythroblastic Anemia

    Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] THIS IS NOT A TRUE DECREASE BUT RESULTS FROM INCREASED MARGINATION BY NEUTROPHILS.[meddean.luc.edu] Out of 70 cases 32 were reported as pancytopenia, 17 were microcytic hypochromic anemia, 10 normocytic normochromic blood picture, 3 dimorphic anemia ,2 bicytopenia, 2 CML[ispub.com]

  • Acute Leukemia

    A 1-year-old boy presented with abnormal complete blood count findings, and was found to have blasts and mild dysgranulopoiesis.[ncbi.nlm.nih.gov] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Initial CBC showed bicytopenia, elevated blood urea, creatinine, and serum uric acid, while abdominal ultrasonography revealed bilateral renal enlargement.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] The indications included pancytopenia (all three cell lines), bicytopenia (two cell lines), and unicytopenia (one cell line).[bcmj.org] The cumulative incidence of bicytopenia or pancytopenia ( Figure 2 B) was similar in patients with classic and intermediate disease ( P .63).[bloodjournal.hematologylibrary.org]

  • Systemic Mastocytosis

    The doctor may want the patient to have a bone scan performed in adults or in children with an abnormal complete blood count (CBC).[medfriendly.com] Although the patient responded to the treatment, the relapse with splenomegaly and bicytopenia was observed after 10 months.[ncbi.nlm.nih.gov] In the eight responders, all of whom had a KIT D816V mutation at any time, mast cell infiltration and tryptase level decreased by 70 % and 29.8 %, respectively; absolute neutrophil[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Primary myelofibrosis is diagnosed using the following procedures: Blood testing: Complete blood count (CBC) looking for abnormal amounts of red and white blood cells and[patientworthy.com] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] Tests A complete blood count (CBC) often shows abnormal blood cell counts.[mpnresearchfoundation.org]

  • Autoimmune Hemolytic Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] Laboratory Tests The initial test for anemia, the complete blood count (CBC), may reveal many abnormal results. Hemoglobin and/or hematocrit may be low.[labtestsonline.org]

  • Brucellosis

    In this paper, we present a case of brucellosis with acute hepatitis and bicytopenia without anaemia.[ncbi.nlm.nih.gov] The diagnostic criteria include fever, hepatosplenomegaly, bicytopenia, high serum ferritin level, decreased natural killer cell activity, elevated soluble CD25 level, high[ncbi.nlm.nih.gov] Finally, a case of brucellosis with acute hepatitis and bicytopenia was treated with a successful outcome.[ncbi.nlm.nih.gov]

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