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31 Possible Causes for Bicytopenia, Complete Blood Count Abnormal, Primary Myelofibrosis

  • Gaucher Disease

    Gaucher disease (GD) and primary myelofibrosis (PMF) share similar clinical and laboratory features, such as cytopenia, hepatosplenomegaly, and marrow fibrosis, often resulting[ncbi.nlm.nih.gov]

  • Myelodysplasia

    WHEN TO SUSPECT MDS In many patients, MDS are asymptomatic and appear as an abnormality on a routine complete blood cell count (CBC) or as part of a workup for anemia.[mdedge.com] 2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] primary MDS (often RAEB2 ) with fibrosis and therapy related myeloid neoplasms with fibrosis Primary Myelofibrosis, Fibrotic Phase MDS with Fibrosis Post-Polycythemia Vera[surgpathcriteria.stanford.edu]

  • Chronic Myeloid Leukemia

    Blood tests Chromosome analysis The diagnosis of CML is suspected when the results of a complete blood count show an abnormally high white blood cell count.[merck.com] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[doi.org] myelofibrosis (PMF).[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Primary myelofibrosis is diagnosed using the following procedures: Blood testing: Complete blood count (CBC) looking for abnormal amounts of red and white blood cells and[patientworthy.com] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] To report ocular manifestations of idiopathic primary myelofibrosis in a patient with relapsed primary myelofibrosis. Observational case report.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] The indications included pancytopenia (all three cell lines), bicytopenia (two cell lines), and unicytopenia (one cell line).[bcmj.org] The cumulative incidence of bicytopenia or pancytopenia ( Figure 2 B) was similar in patients with classic and intermediate disease ( P .63).[bloodjournal.hematologylibrary.org]

  • Leukoerythroblastic Anemia

    Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] An old term, agnogenic myeloid metaplasia, indicates primary myelofibrosis with or without myeloid metaplasia.[merckmanuals.com] PubMed Search : Primary myelofibrosis [title] Page views in 2018: 5,152 Page views in 2019 to date: 2,417 Cite this page: Sangle N. Primary myelofibrosis.[pathologyoutlines.com]

  • Pancytopenia

    The doctor will also do a complete blood count (CBC). This test measures the amount of red blood cells, white blood cells, and platelets in your blood.[healthline.com] […] of bicytopenia and pancytopenia.[ijpmonline.org] myelofibrosis Lymphoma Hairy cell leukaemia Plasma cell myeloma Lysosomal storage diseases Gaucher disease Molecular genetics - genetic disorders.[rcpa.edu.au]

  • Thrombocytopenia

    In a patient who is otherwise in his/her usual state of good health who has not taken a new medication, has thrombocytopenia and no other abnormality found in a complete blood[rarediseases.org] HIV post exposure prophylaxis induced bicytopenia: a case report. AIDS Res Ther . 2014; 11 :11. [ PubMed ] [ DOI ] 8. Visentin GP , Liu CY.[wjgnet.com] count or upon inspection of the blood smear, and has no family history of thrombocytopenia, the diagnosis of ITP is favored.[rarediseases.org]

  • Acute Myelocytic Leukemia

    It has not been treated except to relieve signs and symptoms such as fever, bleeding, or pain, and the following are true: The complete blood count is abnormal.[cancer.gov] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[bloodjournal.hematologylibrary.org] Progression of other blood cancers or disorders, polycythemia vera, primary myelofibrosis, essential thrombocythemia and myelodysplastic syndromes (MDS).[lls.org]

  • Disseminated Intravascular Coagulation

    Disseminated intravascular coagulation (DIC) is a very rare complication of disseminated cytomegalovirus (CMV) infection. So far it is mainly described for immunocompromised patients. A 49-year-old immunocompetent Caucasian male presented with sudden onset of fever and DIC due to primary CMV infection, which was[…][ncbi.nlm.nih.gov]