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50 Possible Causes for Bicytopenia, Decreased Platelet Count

  • Gaucher Disease

    [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia[symptoma.com] Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia) and decreased white blood cell counts (leukopenia) result in easy bruisability and hence black-and-blue[scientificamerican.com] […] blood cell count causing anemia Individuals with anemia may have fatigue, low energy, and decreased exercise tolerance Decreased platelet count can cause easy bruising Bone[dovemed.com]

  • Severe Aplastic Anemia

    Transfusions are given when red cell counts decrease, patients with adequate platelet counts who have blood clots may receive blood thinners, and low white cell and platelet[marrowforums.org]

  • Pancytopenia

    If more than one of the blood cells is low then the condition is called as bicytopenia.[ncbi.nlm.nih.gov] Decrease in all types of white blood cells (revealed by doing a differential count). thrombocytopenia: platelet count 150 109/L. Treatment of the underlying cause.[en.wikipedia.org] Don’t forget: To meet the criteria for HLH, the patient must have the right clinical picture and 5 of the following: fever 38.5C splenomegaly cytopenias (at least bicytopenia[uscmedicine.blog]

  • Disseminated Intravascular Coagulation

    Blood tests revealed a decreased platelet count, disseminated intravascular coagulation (DIC), renal dysfunction, hemolysis, and infection.[ncbi.nlm.nih.gov] Diagnosis is based on presence of 1 known underlying conditions causing DIC plus abnormal global coagulation tests: decreased platelet count, increased prothrombin time, elevated[bestpractice.bmj.com] Some routine tests that may be performed include: CBC (complete blood count) – includes a platelet count ; in DIC, platelets are often low.[labtestsonline.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] If the PNH occurs in the setting of known (or suspected) aplastic anemia, abnormal white blood cell counts and decreased platelet counts may be seen at this.[en.wikipedia.org] RESULTS: We observed a decrease in platelet EV count with eculizumab treatment (p CONCLUSIONS: Eculizumab has an impact on the extent of EV production and on the procoagulant[ncbi.nlm.nih.gov]

  • Drug-induced Bone Marrow Suppression

    Early forms of myelodysplastic syndrome initially can manifest as a single cytopenia or, more often, as a bicytopenia.[emedicine.medscape.com] DIAGNOSIS AND CLINICAL PRESENTATION Agranulocytosis is characterized by a neutrophil granulocyte count 0.5 109/l with no relevant decrease in haemoglobin and platelet counts[flipper.diff.org] […] of platelet count. 4 8 There have been reports of haematological side-effects from an Indian study by Karande and Kshirsagar, who reported them in 3.8% of cases 9 ; however[pmj.bmj.com]

  • Myelodysplasia

    2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] People may also develop symptoms related to a decrease in the platelet or white blood cell count, such as infections (decreased white blood cell count), and easy bruising[oncolink.org] Thrombocytopenia The platelet count is often decreased with abnormal platelets.[patient.info]

  • Acute Leukemia

    A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com] Initial CBC showed bicytopenia, elevated blood urea, creatinine, and serum uric acid, while abdominal ultrasonography revealed bilateral renal enlargement.[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    Case report: A 64-year-old male initially presented with fatigue, splenomegaly, and bicytopenia.[ncbi.nlm.nih.gov] Decreased blood counts (white blood cells, platelets, and red blood cells) are common with IMBRUVICA , but can also be severe.[imbruvica.com] Besides the signs and symptoms caused by mantle cell lymphoma, the major complications of MCL are decreased lifespan and death.[rxlist.com]

  • Castleman Disease

    Investigations showed bicytopenia, nephrotic range proteinuria with hypoalbuminemia, hypogammaglobulinemia, and features of hyaline-vascular type Castleman disease in a lymph[ncbi.nlm.nih.gov] The observed side effects were low platelet counts and low fibrin levels, with no macrophage activation syndrome ( Fig. 1 ) and an episode of herpes zoster.[mct.aacrjournals.org] count (thrombocytopenia) Elevated lymphocytes and plasma cells (polyclonal lymphocytosis and plasmacytosis) Elevated BUN and creatinine (decreased kidney function) Proteinuria[cdcn.org]

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