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54 Possible Causes for Bicytopenia, Easy Bruising

  • Gaucher Disease

    Gaucher Disease [GBA]: Enlargement of spleen and liver, blood abnormalities (anemia, easy bruising, impaired clotting, etc), and bone problems (joint pain, bone fractures,[jewishgeneticdiseases.org] Type 1 - Beta glucocerebrosidase deficency - most common adult type easy bruising Anaemia , Fx treatable w enzyme replacement therapy ( fatal if enzyme subsitute is not given[brainscape.com] Other symptoms may include: Bone pain and fractures Cognitive impairment (decreased thinking ability) Easy bruising Enlarged spleen Enlarged liver Fatigue Heart valve problems[nlm.nih.gov]

  • Severe Aplastic Anemia

    These include fatigue, shortness of breath, fever, recurrent infections, easy bruising or unusual bleeding.[leukemiabmtprogram.org] Platelets are responsible for normal blood clotting and low numbers can result in easy bruising and bleeding which can be deadly.[clinicaltrials.gov] Some symptoms include tiredness, paleness, frequent infections, and easy bruising and bleeding. Aplastic anemia is diagnosed with blood and bone marrow tests.[urmc.rochester.edu]

  • Pancytopenia

    If more than one of the blood cells is low then the condition is called as bicytopenia.[ncbi.nlm.nih.gov] Leukopenia results as frequent, reccurent infections and fever Thrombocytopenia causes easy bruising, nose bleeds, bleeding of gums and unexplained bleeding of the internal[symptoma.com] If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.[en.wikipedia.org]

  • Disseminated Intravascular Coagulation

    Other symptoms are: blood clots decreased blood pressure easy bruising rectal or vaginal bleeding red dots on the surface of the skin ( petechiae ) If you have cancer, DIC[healthline.com]

  • Myelodysplasia

    2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] If you have symptoms, they may include Shortness of breath Weakness or feeling tired Skin that is paler than usual Easy bruising or bleeding Pinpoint spots under the skin[medlineplus.gov] […] results of both blood tests and bone marrow biopsy results. 2016 WHO Classification of MDS Subtype Blood Bone Marrow MDS with single lineage dysplasia (MDS-SLD) Single of bicytopenia[oncolink.org]

  • Acute Leukemia

    A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Symptoms of ALL include: Weakness or feeling tired Fever Easy bruising or bleeding Bleeding under the skin Shortness of breath Weight loss or loss of appetite Pain in the[nlm.nih.gov] Initial CBC showed bicytopenia, elevated blood urea, creatinine, and serum uric acid, while abdominal ultrasonography revealed bilateral renal enlargement.[ncbi.nlm.nih.gov]

  • Leukoerythroblastic Anemia

    Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] The anemia causes fatigue, weakness, and paleness; the leukopenia causes increased susceptibility to infection; the thrombocytopenia causes easy bruising and bleeding.[proz.com] Severe anemia, easy bruising or bleeding, and multiple infections can result because of the lack of healthy blood cells.[oncolink.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] Symptoms Symptoms may include: Abdominal pain Back pain Blood clots, may form in some people Dark urine, comes and goes Easy bruising or bleeding Headache Shortness of breath[mountsinai.org] Symptoms Symptoms may include: Abdominal pain Back pain Blood clots , may form in some people Dark urine, comes and goes Easy bruising or bleeding Headache Shortness of breath[huronregional.org]

  • Primary Myelofibrosis

    Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com] bruising Easy bleeding Excessive sweating during sleep (night sweats) Fever Bone pain When to see a doctor Make an appointment with your doctor if you have any persistent[mayoclinic.org]

  • Familial Hemophagocytic Lymphohistiocytosis

    Hemogram revealed bicytopenia and bone marrow aspirate showed hemophagocytosis.[link.springer.com] A reduction in platelets may cause easy bruising and abnormal bleeding.The brain may also be affected in familial hemophagocytic lymphohistiocytosis.[icdlist.com] […] guidelines of the Histiocyte Society, diagnosis of Hemophagocytic Lympho-histiocytosis (HLH) requires fulfillment of 5 out of 8 criteria – prolonged fever, splenomegaly, bicytopenia[indianpediatrics.net]

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