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36 Possible Causes for Bicytopenia, Epistaxis

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  • Gaucher Disease

    Epistaxis and ecchymoses resulting from thrombocytopenia are common.[merckmanuals.com]

  • Disseminated Intravascular Coagulation

    […] bilateral periorbital oedema and tense orbits in keeping with orbital compartment syndrome (OCS) shortly after presenting to the emergency department for uncontrollable epistaxis[ncbi.nlm.nih.gov] Clinical history can include epistaxis, gingival bleeding, haematuria, oliguria, cough, dyspnoea, fever, delirium, and coma.[bestpractice.bmj.com] […] pathways Activation and/or impairment of fibrinolysis Clinical Presentation Generally occurs in the setting of a risk factor listed above Hemorrhage – petechiae, purpura, epistaxis[arupconsult.com]

  • Myelodysplasia

    2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] Fewer than 20% of patients present with symptoms of isolated thrombocytopenia such as minor bleeding (eg, mucosal bleeding, petechiae, easy bruising, epistaxis) or major bleeding[mdedge.com] […] results of both blood tests and bone marrow biopsy results. 2016 WHO Classification of MDS Subtype Blood Bone Marrow MDS with single lineage dysplasia (MDS-SLD) Single of bicytopenia[oncolink.org]

  • Acute Leukemia

    A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Initial CBC showed bicytopenia, elevated blood urea, creatinine, and serum uric acid, while abdominal ultrasonography revealed bilateral renal enlargement.[ncbi.nlm.nih.gov]

  • Promyelocytic Leukemia

    The patient was treated with all-trans retinoic acid under a diagnosis of APL with improvement of the bicytopenia.[ncbi.nlm.nih.gov] He denied episodes of melena, hematemesis, or hematuria and had no epistaxis. Routine blood work showed pancytopenia and evidence of diffuse intravascular coagulation.[ncbi.nlm.nih.gov] A bone marrow examination in a 19-year-old woman who presented with ecchymoses and epistaxis showed morphologic and immunophenotypic features consistent with APL.[ncbi.nlm.nih.gov]

  • Hypersplenism

    Baijal & Anshu Srivastava Hepatology International (2015) Bone marrow examination in Egyptian patients with bicytopenia/pancytopenia Somaia Mohammed Mousa Comparative Clinical[nature.com] Prior to splenectomy the patient continued to have a marked thrombocytopenia which resulted in recurrent bouts of epistaxis; splenectomy together with tuberculostatic therapy[ncbi.nlm.nih.gov] In addition, symptoms such as epistaxis and gingival bleeding were ameliorated or even eliminated, and the quality of life was improved.[ncbi.nlm.nih.gov]

  • Acute Erythroblastic Leukemia

    The initial diagnoses were chronic myeloid leukemia in two, myelodysplastic syndrome in nine including four cases of Down syndrome, pancytopenia or bicytopenia in three, and[jstage.jst.go.jp]

  • Severe Aplastic Anemia

    On physical examination, the patient looked pale and had a purpuric rash on the limbs and active epistaxis, but no lymphadenopathy or organomegaly.[omicsonline.org] Aplastic anemia may present with the following signs and symptoms: Fatigue Dyspnea on exertion Easy bruising and bleeding (for example, epistaxis, gum bleeding, heavy menses[cancertherapyadvisor.com] Marrow Transplant (BMT) Case Presentation A 17-year-old male patient without any apparent prior diagnosis of an illness presented to our emergency department with heavy epistaxis[omicsonline.org]

  • Evan's Syndrome

    The pattern of occurrence of bicytopenia can delay the diagnosis since it may be coincidental, sequential, or separate, and the time frame between episodes can range from[symptoma.com] The first boy presented at the age of 9-months with recurrent epistaxis and petechia of 3 months' duration.[cags.org.ae] ITP is often revealed by mucocutaneous hemorrhage with epistaxis, petechiae, purpura, and ecchymoses.[orpha.net]

  • Pancytopenia

    If more than one of the blood cells is low then the condition is called as bicytopenia.[ncbi.nlm.nih.gov] Three of the 11 patients had severe thrombocytopenia, and they were admitted with complaints of epistaxis, gingival bleeding, petechiae, and purpura.[ncbi.nlm.nih.gov] If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.[en.wikipedia.org]

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