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112 Possible Causes for Bicytopenia, Fever

  • Severe Aplastic Anemia

    Dengue fever has rarely been reported as an etiology for aplastic anemia. An 8-year-old girl was admitted with fever, myalgia and petechiae.[ncbi.nlm.nih.gov] A 4-year-old girl with severe aplastic anemia and 2 previous failed T-depleted haploidentical peripheral blood stem cell transplants developed persistent neutropenic fever[ncbi.nlm.nih.gov] […] history of diseases similar to dengue fever.[omicsonline.org]

  • Adenovirus Infection

    […] encephalopathy, myocarditis, rash) was diagnosed with adenovirus-associated macrophage activation syndrome according to clinical and laboratory parameters (fever, hepatosplenomegaly, bicytopenia[ncbi.nlm.nih.gov] The elder brother developed a high fever and was diagnosed with HAdV infection with an immunochromatographic kit for HAdV (IC-kit).[ncbi.nlm.nih.gov] […] period of 1-14 days, whereas rhinitis, fever, and cervical lymphadenopathy are typical for pharyngoconjunctival fever (PCF).[symptoma.com]

  • Sepsis

    DIAGNOSIS: The present patient met 5 of the HLH criteria: fever, splenomegaly, bicytopenia, hypertriglyceridemia and/or hypofibrinogenemia, and hyperferritinemia.[ncbi.nlm.nih.gov] After discussing the physiological aspects of fever production, the present review aims to delineate the advantages and drawbacks of fever in septic patients.[ncbi.nlm.nih.gov] A 32-year-old female presented with fever and generalised malaise to a rural hospital in Ghana.[ncbi.nlm.nih.gov]

  • Pseudogout

    Minor adverse events (AE) did not differ in frequency between the groups, but the only serious AE occurred on MTX (bicytopenia).[ncbi.nlm.nih.gov] The patient exhibited severe neck pains, headache, high fever and a pain in his knee joints together with symptoms of the central nervous system.[ncbi.nlm.nih.gov] She had a moderately high fever (37.5 C), and her neck pain was so severe that she could not move her neck in any direction.[ncbi.nlm.nih.gov]

  • Disseminated Intravascular Coagulation

    Abstract Objective Cases of Japanese spotted fever (JSF) are sometimes complicated by disseminated intravascular coagulation (DIC) with an abnormal liver function, resulting[ncbi.nlm.nih.gov] There was no other explanation for the fever and rash, including infection, malignancy, and collagenosis.[ncbi.nlm.nih.gov] Although DIC resolved, subsequent fever persisted for approximately 1 month (postoperative days 67-103).[ncbi.nlm.nih.gov]

  • Agranulocytosis

    Since there was a possibility of autoimmune etiology for bicytopenia, rheumatology opinion was sought following which CANCA (cytoplasm antineutrophil cytoplasmic antibodies[ncbi.nlm.nih.gov] Here is the case of a 14-year Thai boy presenting with fever and diarrhea for 3 days.[ncbi.nlm.nih.gov] Here we present a case of a 4-year-old boy who developed life-threatening agranulocytosis, anemia, and marked plasmacytosis in his bone marrow after dipyrone use for fever[ncbi.nlm.nih.gov]

  • Drug-induced Neutropenia

    Bicytopenia: adverse effect of risperidone. Current Psychiatry. 2014;13(4):E1. 5. Meylan C, Bondolfi G, Aubert AC, Baumann P.[dovepress.com] In any case, the clinical presentation is distinguished by the appearance of localized infections, and in more severe neutropenia, systemic signs (fever, malaise, weight loss[symptoma.com] Patients typically experience acute, severe neutropenia, or agranulocytosis ( 9 neutrophils/L) and symptoms of fever, chills, sore throat, and muscle and joint pain.[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    Further investigation revealed bicytopenia with splenomegaly and elevated serum creatinine.[ncbi.nlm.nih.gov] He had fever, night sweats, and weight loss (B-symptoms), along with lymphadenopathy and elevated serum lactate dehydrogenase, with no prior history of lymphoma.[ncbi.nlm.nih.gov] A 64-year-old male initially presented with fatigue, splenomegaly, and bicytopenia. The bone marrow biopsy specimen revealed extensive infiltration with MCL.[ncbi.nlm.nih.gov]

  • Hepatosplenic Lymphoma

    There was bicytopenia (hemoglobin - 101 g/L, platelet count - 38 10 9 /L, and total leukocyte count - 5 10 9 /L) with only a few blasts in peripheral blood film [Figure 1][ijpmonline.org] Blood 2014 124:677; doi: A 30-year-old man with an unremarkable medical history presented with fever, anemia, and thrombocytopenia, along with hepatosplenomegaly, for 1 month[bloodjournal.org] Patients present with systemic symptoms (fever), abdominal pain, weakness, and marked hepatosplenomegaly in the absence of lymphadenopathy.[ncbi.nlm.nih.gov]

  • Castleman Disease

    Investigations showed bicytopenia, nephrotic range proteinuria with hypoalbuminemia, hypogammaglobulinemia, and features of hyaline-vascular type Castleman disease in a lymph[ncbi.nlm.nih.gov] A 46-year-old male patient presented with fever for over 5 months. An FDG PET/CT was acquired to evaluate the source of the fever.[ncbi.nlm.nih.gov] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov]

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