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43 Possible Causes for Bicytopenia, Hemoglobin Decreased

  • Gaucher Disease

    [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia[symptoma.com] Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia) and decreased white blood cell counts (leukopenia) result in easy bruisability and hence black-and-blue[scientificamerican.com] Mean hemoglobin concentration and platelet count increased by 2.2 g/dL and 113%, respectively.[doi.org]

  • Severe Aplastic Anemia

    Too few red blood cells lead to a decrease in hemoglobin and symptoms of fatigue.[childrenshospital.org]

  • Pancytopenia

    If more than one of the blood cells is low then the condition is called as bicytopenia.[ncbi.nlm.nih.gov] Decrease in all types of white blood cells (revealed by doing a differential count). thrombocytopenia: platelet count 150 109/L. Treatment of the underlying cause.[en.wikipedia.org] Don’t forget: To meet the criteria for HLH, the patient must have the right clinical picture and 5 of the following: fever 38.5C splenomegaly cytopenias (at least bicytopenia[uscmedicine.blog]

  • Paroxysmal Nocturnal Hemoglobinuria

    Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] Blood complete picture showed decreased hemoglobin and reticulocytosis upto 30%.[ncbi.nlm.nih.gov] Together, these results argue that the decline in hemoglobin A1c was due to decreased RBC survival secondary to PNH.[ncbi.nlm.nih.gov]

  • Disseminated Intravascular Coagulation

    Am J Med Sci. 2013 Dec;346(6):514-6. doi: 10.1097/MAJ.0b013e31829e02d3. Author information 1 Department of Internal Medicine (CS), Lehigh Valley Health Network, Allentown, Pennsylvania; and Pulmonary and Critical Care Medicine (DSL), Lehigh Valley Health Network, Allentown, Pennsylvania. Abstract Acute perturbations in[…][ncbi.nlm.nih.gov]

  • Drug-induced Bone Marrow Suppression

    Early forms of myelodysplastic syndrome initially can manifest as a single cytopenia or, more often, as a bicytopenia.[emedicine.medscape.com] Cells Affected in Myelosuppression Myelosuppression can result in decreased production of: Red blood cells (RBCs): Red blood cells contain hemoglobin, the protein that is[verywell.com]

  • Myelodysplasia

    2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] […] is decreased.[danafarberbostonchildrens.org] […] results of both blood tests and bone marrow biopsy results. 2016 WHO Classification of MDS Subtype Blood Bone Marrow MDS with single lineage dysplasia (MDS-SLD) Single of bicytopenia[oncolink.org]

  • Castleman Disease

    Investigations showed bicytopenia, nephrotic range proteinuria with hypoalbuminemia, hypogammaglobulinemia, and features of hyaline-vascular type Castleman disease in a lymph[ncbi.nlm.nih.gov] (anemia), low platelet count (thrombocytopenia) Elevated lymphocytes and plasma cells (polyclonal lymphocytosis and plasmacytosis) Elevated BUN and creatinine (decreased[cdcn.org] […] following abnormal blood test results (also listed on the Diagnostic Criteria ): Elevated erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and fibrinogen Low hemoglobin[cdcn.org]

  • Primary Myelofibrosis

    Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] Deferasirox treatment improved the hemoglobin level and decreased transfusion requirements in four patients with the myelodysplastic syndrome and primary myelofibrosis.[doi.org] Spleen size decreased further to 13 cm.[dovepress.com]

  • Autoimmune Hemolytic Anemia

    Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] Laboratory data revealed progressive decrease in hemoglobin during her hospitalization due to pulmonary infection in 2016.[ncbi.nlm.nih.gov] Hemoglobin is decreased, but the degree of anemia depends on the compensatory capacity of the bone marrow.[clinlabnavigator.com]

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