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29 Possible Causes for Bicytopenia, Hepatosplenomegaly, Monocyte Count Increased

  • Gaucher Disease

    We report here the case of a young woman with hepatosplenomegaly, leukopenia, and thrombocytopenia.[ncbi.nlm.nih.gov] [ncbi.nlm.nih.gov] Less common signs of the disease are hepatosplenomegaly, ichthyosis, arthrogryposis and facial dysmorphy.[symptoma.com] Laboratory studies that show anemia and other hematological abnormalities, together with marked hepatosplenomegaly will usually indicate a bone marrow biopsy, which will show[symptoma.com]

  • Acute Leukemia

    The leukocyte count is usually increased monocytic cells (monoblast, promoncytes, monocytes), are increased to 5000/L or more.[intechopen.com] Physical examination showed jaundice, hepatosplenomegaly, and peripheral facial nerve palsy in addition to dermal nodules.[ncbi.nlm.nih.gov] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    JMML characteristically presents with hepatosplenomegaly, lymphadenopathy, fever, and skin rash along with an elevated white blood cell (WBC) count and increased circulating[northshore.org] In all three patients, radionuclide imaging with technetium-99m sulfur colloid showed hepatosplenomegaly, decreased liver uptake, and increased splenic activity.[ncbi.nlm.nih.gov] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[bloodjournal.hematologylibrary.org]

  • Brucellosis

    Abstract Brucellosis is a systemic zoonotic infectious disease that may cause fever, fatigue, sweating, arthritis, hepatosplenomegaly, cytopenia, and lymphadenopathy.[ncbi.nlm.nih.gov] In this paper, we present a case of brucellosis with acute hepatitis and bicytopenia without anaemia.[ncbi.nlm.nih.gov] On examination in an emergency room, abdomen palpation was normal with hepatosplenomegaly and the results of a liver function test were elevated.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] Computed tomography (CT) of the chest, abdomen and pelvis was remarkable for hepatosplenomegaly.[jmedicalcasereports.com]

  • Chronic Myelomonocytic Leukemia

    The Mayo prognostic model classified CMML patients into three risk groups based on: increased absolute monocyte count, presence of circulating blasts, hemoglobin 9 /L.[mayoclinic.pure.elsevier.com] Affected individuals present with monocytosis, cytopenias, and extramedullary manifestations like lymphadenopathy and hepatosplenomegaly.[symptoma.com] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[doi.org]

  • Disseminated Tuberculosis

    Disseminated tuberculosis can present in various ways including prolonged fever / pyrexia of unknown origin, hepatosplenomegaly, lymphadenopathy, meningitis and rarely extreme[ncbi.nlm.nih.gov] Patients and Methods 312 bone marrow aspirates from patients with the diagnosis of anaemia, severe granulocytopenia, thrombocytopenia, bicytopenia or pancytopenia, referred[tbonline.info] Clinical examination revealed diffuse macular rash, severe pallor, deep icterus, generalised lymphadenopathy and hepatosplenomegaly.[ncbi.nlm.nih.gov]

  • Leukoerythroblastic Anemia

    Peripheral blood monocytes, fibrous tissue and cellularity in bone marrow are increased in MDS (22, 23).[ispub.com] Usually there is hepatosplenomegaly due to myeloid metaplasia in which, in addition to leukoblastic cells, erythroblasts are constantly prominent and giant cells[jamanetwork.com] Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org]

  • Acute Megakaryocytic Leukemia

    Leucocytosis is present in 30–50 % of cases of TAM and typically includes increased neutrophils, myelocytes, monocytes and basophils [ 11 ••, 31, 33 ••].[doi.org] The results indicated that the fever, hemorrhage, hepatosplenomegaly and lymphadenopathy in this case were the primary presentations accompanying by leukocytosis, anemia and[ncbi.nlm.nih.gov] The patient’s medical history was consistent with intermittent low-grade fever associated with bicytopenia (neutropenia and thrombocytopenia) for the last 3 years.[dovepress.com]

  • Lymphopenic Agammaglobulinemia - Short-Limbed Dwarfism Syndrome

    […] and normal or increased blood monocyte counts and immunoglobulin levels.[medtextfree.wordpress.com] […] meningitis, mental retardation, headache lymphatic splenomegaly, occasional lymphadenopathy splenomegaly, occasional lymphadenopathy cervical adenopathy in children not seen rare hepatosplenomegaly[ufrgs.br] Copper deficiency can cause neutropenia in patients on total parenteral nutrition, with a history of gastrectomy, and in malnourished children 86, 87, 88 and the bicytopenia[oncohemakey.com]

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