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66 Possible Causes for Bicytopenia, Jaundice

  • Gaucher Disease

    Investigations General assessment FBC and differential (assess the degree of pancytopenia); LFTs (minor elevations of liver enzymes are common but jaundice is a poor prognostic[patient.info] The gastrointestinal features include hepatosplenomegaly, jaundice , hepatic (liver) failure, and ascites (fluid in the abdomen).[medicinenet.com]

  • Severe Aplastic Anemia

    Symptoms include fatigue, pale skin, fast heartbeat (tachycardia), trouble breathing, chills, backache, and yellow skin ( jaundice ).[webmd.com] If you have PNH, you have a higher risk of developing blood. which can cause symptoms such as severe leg, abdominal or chest pain, shortness of breath, jaundice or headache[ohsu.edu] A subset of patients with aplastic anemia present with jaundice and evidence of clinical hepatitis. [1, 2] Findings of adenopathy or organomegaly should suggest an alternative[emedicine.medscape.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    Although the severe obstructive jaundice requiring endoscopic therapy following cholecystectomy was complicated, critical intravascular hemolysis and thrombosis were not observed[ncbi.nlm.nih.gov] Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] Abstract The authors report a 57-year-old male patient who presented with diarrhea, darkened urine, jaundice and increased blood urea nitrogen and creatinine.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] Abstract A 48 year old lady presented with jaundice and exertional breathlesness.[ncbi.nlm.nih.gov]

  • Cytomegalovirus Infection

    RATIONALE: Septo-optic dysplasia (SOD) is a rare congenital disorder that may cause jaundice in infants.[ncbi.nlm.nih.gov] Laboratory investigations showed bicytopenia from complete blood count. Chest radiography and high-resolution computed tomography of the chest revealed lung nodules.[symbiosisonlinepublishing.com] Common symptomatic characteristics of the virus include microcephaly, jaundice, liver-spleen infections, pneumonia, cardiac anomalies, chorioretinitis, vision loss, sensory-neural[ncbi.nlm.nih.gov]

  • Evan's Syndrome

    Abstract A man aged 35 years with a history of Evan's syndrome presented to the clinic with jaundice and shortness of breath, with further testing indicating a relapse of[ncbi.nlm.nih.gov] The pattern of occurrence of bicytopenia can delay the diagnosis since it may be coincidental, sequential, or separate, and the time frame between episodes can range from[symptoma.com] He was pale, jaundiced, with multiple petechia and generalized joint hypermobility.[cags.org.ae]

  • Drug-Induced Autoimmune Hemolytic Anemia

    He became jaundiced with yellow sclera. Observe the photograph of his peripheral blood smear.[labce.com] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] Jaundice: AIHA presents with elevated unconjugated bilirubin, but the presence of conjugated billirun prompt investigation into possible liver disease via blood levels of[pedclerk.bsd.uchicago.edu]

  • Hepatosplenic Lymphoma

    Symptoms include fever, fatigue, jaundice, and infections. Tests often reveal abnormal liver function and reduced peripheral blood cells.[rosenfeldinjurylawyers.com] There was bicytopenia (hemoglobin - 101 g/L, platelet count - 38 10 9 /L, and total leukocyte count - 5 10 9 /L) with only a few blasts in peripheral blood film [Figure 1][ijpmonline.org] She consulted her general practitioner and was admitted to a primary care hospital for acute hepatic failure with jaundice (total bilirubin 6.4 mg/dL, direct bilirubin 5.3[ghrnet.org]

  • Pancytopenia

    Such relevant features such as pallor, jaundice, bleeding, splenomegaly and so on are dealt with either in passing or in relation first to another system or the ‘general examination[books.google.de] If more than one of the blood cells is low then the condition is called as bicytopenia.[ncbi.nlm.nih.gov] .  Weight loss, fever ( Inflammatory or malignancy)  Jaundice ( Hepatitis B or C)  Joint pain (SLE)  History of blood loss 7.[slideshare.net]

  • Sepsis

    […] accumulation Impaired oxygenation PaO 2 /FIO 2 Mechanical ventilation with low tidal volume and PEEP Liver Disturbed intracellular and extracellular bile salt transport Jaundice[doi.org] DIAGNOSIS: The present patient met 5 of the HLH criteria: fever, splenomegaly, bicytopenia, hypertriglyceridemia and/or hypofibrinogenemia, and hyperferritinemia.[ncbi.nlm.nih.gov] Sepsis-associated hepatic dysfunction is clinically recognized by jaundice or cholestasis and is caused by various underlying mechanisms such as the impairment of energy-dependent[doi.org]

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