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121 Possible Causes for Bicytopenia, Leukemia

  • Paroxysmal Nocturnal Hemoglobinuria

    The indications included pancytopenia (all three cell lines), bicytopenia (two cell lines), and unicytopenia (one cell line).[bcmj.org] […] chromosomal abnormalities involving chromosome bands 13q12 to 13q14 (13q12q14) are frequently found in various hematologic malignancies, including chronic lymphoblastic leukemia[ncbi.nlm.nih.gov] Evolutions to myelodysplastic syndrome or acute leukemia were similar in both cohorts. There was less evolution to aplastic anemia in the treatment group.[ncbi.nlm.nih.gov]

  • Systemic Mastocytosis

    Although the patient responded to the treatment, the relapse with splenomegaly and bicytopenia was observed after 10 months.[ncbi.nlm.nih.gov] Leukemia 2007; [Epub ahead of print] Google Scholar 12.[link.springer.com] Herein, we report a case of 14-year-old girl with SM associated with acute myeloid leukemia with maturation with t(8;21).[ncbi.nlm.nih.gov]

  • Hypersplenism

    Bone marrow examination in Egyptian patients with bicytopenia/pancytopenia Somaia Mohammed Mousa Comparative Clinical Pathology (2015) 5.[nature.com] A 45-year-old woman with previously diagnosed chronic type adult T-cell leukemia (ATL) presented with abdominal discomfort and red eruptions on her arms and legs.[ncbi.nlm.nih.gov] We report a case of Chronic lymphocytic leukemia (CLL) with associated hypersplenism, that was referred to us for partial splenic embolization (PSE) as the patient was not[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    A 56-year-old male with chronic idiopathic myelofibrosis and cytogenetic finding of 20q- after a period of 10 months developed acute Philadelphia-positive lymphoblastic leukemia[ncbi.nlm.nih.gov] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] The molecular pathogenesis underlying the primary myelofibrosis (PMF) progression to acute myeloid leukemia (AML) is still not well defined.[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    A 64-year-old male initially presented with fatigue, splenomegaly, and bicytopenia. The bone marrow biopsy specimen revealed extensive infiltration with MCL.[ncbi.nlm.nih.gov] The concurrent presentation of mantle cell lymphoma with large granular lymphocytic leukemia simultaneously has never been reported.[ncbi.nlm.nih.gov] Morphology of peripheral blood and immunophenotyping by flow cytometry pointed to a diagnosis of chronic lymphocytic leukemia.[ncbi.nlm.nih.gov]

  • Promyelocytic Leukemia

    The patient was treated with all-trans retinoic acid under a diagnosis of APL with improvement of the bicytopenia.[ncbi.nlm.nih.gov] Promyelocytic leukemia (PL) is a hematopoietic malignancy and more specifically a type of acute myelogenous leukemia (AML), which is characterized by the increased levels[symptoma.com] 90% according to one study. [5] [4] [6] Contents Signs and symptoms Edit The symptoms tend to be similar to AML in general with the following being possible symptoms: [7] Bicytopenia[en.m.wikipedia.org]

  • Refractory Anemia with Excess Blasts

    Diagnosis Comment: There is leukocytosis and bicytopenia (normocytic anemia and thrombocytopenia).[gpec.ubc.ca] Disease subsets consisted of patients with acute non-lymphocytic leukemia (ANLL) over age 60; ANLL refractory to standard therapy; smouldering leukemia; and refractory anemia[ncbi.nlm.nih.gov] Refractory cytopenia with multilineage dysplasia is characterized by bicytopenia or pancytopenia.[businessandleadership.com]

  • Penicillamine

    Cessation of D-Pen and the start of corticosteroid therapy were followed by recovery from bicytopenia.[ncbi.nlm.nih.gov] The H(2)O(2)-mediated cytotoxicity was greater in leukemia cells compared to breast cancer cells.[ncbi.nlm.nih.gov] D-pen alone was shown not to enter leukemia cells.[ncbi.nlm.nih.gov]

  • Chlamydophila Pneumoniae

    In this study, we explored the molecular mechanism involved in C. pneumoniae infection by using human acute T cell leukemia cell line, Jurkat E6-1.[ncbi.nlm.nih.gov] Laboratory work up revealed bicytopenia (white cell count 1.37 10(9)/L, platelets 60 10(9)/L) and an increase in C reactive protein (9 mg/dL).[ncbi.nlm.nih.gov]

  • Leprosy

    Leukemic skin infiltrations in patients with leukemia are referred to as leukemia cutis.[ncbi.nlm.nih.gov] While on antileprosy treatment, he developed unexplained persistent fever, organomegaly, bicytopenia, and elevated rate of inflammatory markers with bone marrow aspirate showing[ncbi.nlm.nih.gov] It can be seen in all types of leukemia, especially in patients with acute myelomonocytic leukemia (AML).[ncbi.nlm.nih.gov]

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