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86 Possible Causes for Bicytopenia, Leukocytosis

  • Mantle Cell Lymphoma

    A 64-year-old male initially presented with fatigue, splenomegaly, and bicytopenia. The bone marrow biopsy specimen revealed extensive infiltration with MCL.[ncbi.nlm.nih.gov] A 60-year-old male patient presented with obvious leukocytosis and progressive weakness.[ncbi.nlm.nih.gov] Splenomegaly is often massive, while aberrant WBC count may be seen, either as markedly high leukocytosis or pancytopenia.[symptoma.com]

  • Sepsis

    The present patient met 5 of the HLH criteria: fever, splenomegaly, bicytopenia, hypertriglyceridemia and/or hypofibrinogenemia, and hyperferritinemia.[ncbi.nlm.nih.gov] […] ascendant and descendant thoracic aortic aneurysm, presenting 7 years after thoracic endovascular aneurysm repair with thoracic pain, fever, inflammatory indexes increase, leukocytosis[ncbi.nlm.nih.gov] They include malaise, leukocytosis, tachypnoea, and pulse 90 bpm. Sepsis can progress rapidly to multi-organ failure and shock, and is often fatal.[bestpractice.bmj.com]

  • Leukemoid Reaction

    Results: The patient died of multiple organ failure 2 months after being diagnosed with leukocytosis.[dovepress.com] Infection induced hemophagocytic lymphohistiocytosis with a leukemoid reaction was suspected because of fever, splenomegaly and bicytopenia in conjunction with elevated serum[ncbi.nlm.nih.gov] Although a leukocytosis of 15,000-18,000 cells/mm(3) is frequently seen in AH, LRs are rare in this context.[ncbi.nlm.nih.gov]

  • Hypereosinophilic Syndrome

    ): almost exclusively in males with FIP1L1-PDGFRA fusion (FIP1-like-1 fused with platelet-derived growth factor receptor alpha [F/P] 2 and increased serum vitamin B 12 , bicytopenia[unboundmedicine.com] Abstract This report concerns three individuals with a similar illness characterized by the following: a striking leukocytosis due primarily to increased numbers of mature[annals.org] Leukocytosis above 90,000 cells per microliter is a bad prognostic indication.[symptoma.com]

  • Primary Myelofibrosis

    Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] Leukocytosis is occasionally seen in patients with presumptive but undiagnosed myeloproliferative disorders (MPD).[ncbi.nlm.nih.gov] […] for the diagnosis of pre-fibrotic/early primary myelofibrosis (pre-PMF) require at least one of the following four borderline expressed minor clinical criteria: anemia, leukocytosis[ncbi.nlm.nih.gov]

  • Acute Erythroblastic Leukemia

    The initial diagnoses were chronic myeloid leukemia in two, myelodysplastic syndrome in nine including four cases of Down syndrome, pancytopenia or bicytopenia in three, and[jstage.jst.go.jp] The major clinical manifestations of malaise, hepatosplenomegaly, anemia, and leukocytosis are related to abnormal, excessive, unrestrained overgrowth of granulocytes in the[medical-dictionary.thefreedictionary.com] […] nose bleed or bruises all over Bone pain (expanding marrow) Organ infiltration (liver, spleen, brain) Laboratory Findings in Acute Leukemia Blasts/immature cells in blood Leukocytosis[quizlet.com]

  • Acute Leukemia

    A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Dysplasia is an abnormal development of immature cells in the presence of leukocytosis (increased WBC count).[healthline.com] Initial CBC showed bicytopenia, elevated blood urea, creatinine, and serum uric acid, while abdominal ultrasonography revealed bilateral renal enlargement.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] Mild leukocytosis and thrombocytosis may be present.[clinlabnavigator.com] There was no fever, leukocytosis, or pertinent travel history to suggest malaria or babesiosis, and there was no evidence of spider or insect bites.[casesjournal.biomedcentral.com]

  • Familial Hemophagocytic Lymphohistiocytosis

    Hemogram revealed bicytopenia and bone marrow aspirate showed hemophagocytosis.[link.springer.com] Leukocytosis was detected with circulating "atypical" lymphoid cells.[ncbi.nlm.nih.gov] […] guidelines of the Histiocyte Society, diagnosis of Hemophagocytic Lympho-histiocytosis (HLH) requires fulfillment of 5 out of 8 criteria – prolonged fever, splenomegaly, bicytopenia[indianpediatrics.net]

  • Refractory Anemia

    Diagnosis Comment: There is leukocytosis and bicytopenia (normocytic anemia and thrombocytopenia).[gpec.ubc.ca] Three patients had mild leukocytosis (WBC count, 3,900-16,300/μL [3.9-16.3 10(9)/L]). Ring sideroblasts were 8% to 75% in the bone marrow.[ncbi.nlm.nih.gov] MDS Type Blood Marrow Refractory cytopenia with unilineage dysplasia (RCUD) Refractory anemia (RA) Refractory neutropenia (RN) Refractory thrombocytopenia (RT) Uni- or bicytopenia[slideshare.net]

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