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75 Possible Causes for Bicytopenia, Leukocytosis

  • Sepsis

    DIAGNOSIS: The present patient met 5 of the HLH criteria: fever, splenomegaly, bicytopenia, hypertriglyceridemia and/or hypofibrinogenemia, and hyperferritinemia.[ncbi.nlm.nih.gov] […] ascendant and descendant thoracic aortic aneurysm, presenting 7 years after thoracic endovascular aneurysm repair with thoracic pain, fever, inflammatory indexes increase, leukocytosis[ncbi.nlm.nih.gov] They include malaise, leukocytosis, tachypnoea, and pulse 90 bpm. Sepsis can progress rapidly to multi-organ failure and shock, and is often fatal.[bestpractice.bmj.com]

  • Leukemoid Reaction

    Infection induced hemophagocytic lymphohistiocytosis with a leukemoid reaction was suspected because of fever, splenomegaly and bicytopenia in conjunction with elevated serum[ncbi.nlm.nih.gov] Results: The patient died of multiple organ failure 2 months after being diagnosed with leukocytosis.[dovepress.com] Although a leukocytosis of 15,000-18,000 cells/mm(3) is frequently seen in AH, LRs are rare in this context.[ncbi.nlm.nih.gov]

  • Paraneoplastic Syndrome

    More on polymyalgia rheumatica (PMR) as a paraneoplastic rheumatic syndrome in the elderly (bicytopenia and PMR preceding acute myeloid leukemia).[ncbi.nlm.nih.gov] Published September 1989 Abstract Previously we reported that a clonal squamous cell carcinoma cell line (T3M-1) derived from a lower jaw cancer of a patient with marked leukocytosis[cancerres.aacrjournals.org] Although a leukocytosis was detected, no evidence of infection was acquired and empirical antibiotic treatment was ineffective.[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    Further investigation revealed bicytopenia with splenomegaly and elevated serum creatinine.[ncbi.nlm.nih.gov] A 60-year-old male patient presented with obvious leukocytosis and progressive weakness.[ncbi.nlm.nih.gov] A 64-year-old male initially presented with fatigue, splenomegaly, and bicytopenia. The bone marrow biopsy specimen revealed extensive infiltration with MCL.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] Leukocytosis is occasionally seen in patients with presumptive but undiagnosed myeloproliferative disorders (MPD).[ncbi.nlm.nih.gov] 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia and leukocytosis[ncbi.nlm.nih.gov]

  • Disseminated Intravascular Coagulation

    Disseminated intravascular coagulation (DIC) is a very rare complication of disseminated cytomegalovirus (CMV) infection. So far it is mainly described for immunocompromised patients. A 49-year-old immunocompetent Caucasian male presented with sudden onset of fever and DIC due to primary CMV infection, which was[…][ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[bloodjournal.hematologylibrary.org] Thus, the bone marrow and peripheral blood are characterized by leukocytosis with a predominance of immature cells, primarily blasts.[ncbi.nlm.nih.gov] Additional karyotype abnormalities evolved increasingly, and leukocytosis with blasts with more complex karyotypic abnormalities appeared 5 months later.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[doi.org] Her disease was managed during pregnancy using interferon-α alone despite persistent leukocytosis.[ncbi.nlm.nih.gov] One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov]

  • Hypereosinophilic Syndrome

    F/P HES): almost exclusively in males with FIP1L1-PDGFRA fusion (FIP1-like-1 fused with platelet-derived growth factor receptor α [F/P] and increased serum vitamin B 12, bicytopenia[unboundmedicine.com] Abstract This report concerns three individuals with a similar illness characterized by the following: a striking leukocytosis due primarily to increased numbers of mature[annals.org] […] eosinophil-induced tissue/organ damage. [ Orphanet : 168956 ] Synonyms: Idiopathic Hypereosinophilic Syndrome, hypereosinophilic syndrome, hypereosinophilic disorder, HES, eosinophilic leukocytosis[ebi.ac.uk]

  • Acute Erythroblastic Leukemia

    The initial diagnoses were chronic myeloid leukemia in two, myelodysplastic syndrome in nine including four cases of Down syndrome, pancytopenia or bicytopenia in three, and[jstage.jst.go.jp] The major clinical manifestations of malaise, hepatosplenomegaly, anemia, and leukocytosis are related to abnormal, excessive, unrestrained overgrowth of granulocytes in the[medical-dictionary.thefreedictionary.com] […] nose bleed or bruises all over Bone pain (expanding marrow) Organ infiltration (liver, spleen, brain) Laboratory Findings in Acute Leukemia Blasts/immature cells in blood Leukocytosis[quizlet.com]

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