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36 Possible Causes for Bicytopenia, Macrocytosis

  • Severe Aplastic Anemia

    Mild anemia and macrocytosis may indicate SAA in patients otherwise possibly diagnosed with immune thrombocytopenic purpura.[symptoma.com] Although the anemia is often normocytic, mild macrocytosis can also be observed in association with stress erythropoiesis and elevated fetal hemoglobin levels.[emedicine.medscape.com]

  • Vitamin B12 Deficiency

    Laboratory data revealed bicytopenia with macrocytic anemia and methylmalonic acid in the urine, consistent with vitamin B12 deficient anemia.[ncbi.nlm.nih.gov] We report a case of a 46-year-old Moroccan man presenting with severe hemolytic anemia, thrombocytopenia, and renal failure in absence of macrocytosis, thus mimicking a genuine[ncbi.nlm.nih.gov] There were no clinical or biological signs of maternal anaemia or macrocytosis. Treatment with oral vitamin B12 rapidly improved the biological findings of the child.[ncbi.nlm.nih.gov]

  • Pancytopenia

    […] of bicytopenia and pancytopenia.[ijpmonline.org] Macrocytosis Howel jolly bodies Basophilic stippling Hypersegmented Neutrophil Megaloblastic anemia 15.[slideshare.net] […] deciliter [normal range, 14 to 18]; hematocrit, 14.5% [normal range, 40 to 52]; and platelets, 56,000 per cubic millimeter [normal range, 150,000 to 440,000]) as well as macrocytosis[nejm.org]

  • Refractory Megaloblastic Anemia

    CLASSIFICATION OF MDS (2008) SUBTYPE BLOOD BONE MARROWREFRACTORY ANEMIA; UNILINEAGECYTOPENIA WITH NO OR RARE BLASTS DYSPLASIA 10%UNILINEAGE UNICYTOPENIA CELLS IN ONEDYSPLASIA (RCUD) BICYTOPENIA[slideshare.net] Nonalcoholic liver disease and hypothyroidism account for a substantial portion of macrocytosis.[aafp.org] Macrocytosis is a common finding in clinical settings .[enotes.tripod.com]

  • Acute Erythroblastic Leukemia

    The initial diagnoses were chronic myeloid leukemia in two, myelodysplastic syndrome in nine including four cases of Down syndrome, pancytopenia or bicytopenia in three, and[jstage.jst.go.jp] Blood smear shows nucleated red cells at different stages with pathological features (macrocytosis, schistocytes, blast cells Bone marrow biopsy shows prevalence of erythroid[patient.info]

  • Leukoerythroblastic Anemia

    Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] The FBE shows - reticulocytosis, anisocytosis, macrocytosis, normochromia, leucopenia, neutropenia with plentiful platelets. Probable diagnosis: A. B12 deficiency B.[kerrybrandis.com] Mild macrocytosis is sometimes seen in myelodysplastic syndromes.[cancertherapyadvisor.com]

  • Refractory Anemia with Excess Blasts in Transformation

    ) Anemia Blasts 1% Erythroid dysplasia only Blasts 5% Ringsideroblasts ³ 15% (count on erythroblasts) Refractory cytopenia with multilineage dysplasia (RCMD) Cytopenias (bicytopenia[w1.uzleuven.be] Macrocytosis is present in most patients. Reactive lymphadenopathy because of a local infection can also be observed.[pedimds.org] […] results of both blood tests and bone marrow biopsy results. 2016 WHO Classification of MDS Subtype Blood Bone Marrow MDS with single lineage dysplasia (MDS-SLD) Single of bicytopenia[oncolink.org]

  • Thrombocytopenia

    HIV post exposure prophylaxis induced bicytopenia: a case report. AIDS Res Ther . 2014; 11 :11. [ PubMed ] [ DOI ] 8. Visentin GP , Liu CY.[wjgnet.com] Mild to moderate Findings range from normal to evidence of cirrhosis or hepatic failure Positive screening questionnaire, abnormal liver function tests (AST/ALT 2, GGT), macrocytosis[aafp.org] […] with a haematologist is reasonable if the platelet count is less than 100 10 9 /L or the patient also has anaemia, neutropenia, or other changes in the blood count - eg, macrocytosis[patient.info]

  • Evan's Syndrome

    The pattern of occurrence of bicytopenia can delay the diagnosis since it may be coincidental, sequential, or separate, and the time frame between episodes can range from[symptoma.com] […] that was found in our patient, it can be explained by reticulocytosis (18.7%), which may give a false, spurious macrocytosis.[sjmms.net] […] of these cases, the Coombs is negative. 9, 10 The diagnosis for Evans is performed as a result of laboratory findings of anemia and thrombocytopenia with polychromasia, macrocytosis[scielo.sa.cr]

  • Drug-induced Bone Marrow Suppression

    Early forms of myelodysplastic syndrome initially can manifest as a single cytopenia or, more often, as a bicytopenia.[emedicine.medscape.com] Occurs in some dog breeds, especially Poodles, in which there are maturation abnormalities of erythrocytes with macrocytosis and hypersegmented neutrophils. bone marrow spaces[medical-dictionary.thefreedictionary.com] Lamivudine associated macrocytosis in HIV infected patients. Int J STD AIDS 18, 39 –40. [CrossRef] [Google Scholar] Kumarasamy, N., Vallabhaneni, S., Cecelia, A.[jmm.microbiologyresearch.org]

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