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89 Possible Causes for Bicytopenia, Pallor

  • Acute Leukemia

    A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] The first case is a 4-year-old girl who presented with pallor and abdominal enlargement.[ncbi.nlm.nih.gov] The initial manifestations of leukemia are generally signs of bone marrow failure, such as pallor, fatigue, fever, bleeding, and infection related to peripheral blood cytopenias[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    The indications included pancytopenia (all three cell lines), bicytopenia (two cell lines), and unicytopenia (one cell line).[bcmj.org] […] disorder with insidious onset (usually in the third or fourth decade) and chronic course, characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor[medical-dictionary.thefreedictionary.com] Pallor, fatigue and stress dyspnea with activity are the usual manifestations.[orpha.net]

  • Malaria

    The prevalence of cytopenias were; 29.6, 48.0% for anemia, 38.9, 12.0% for thrombocytopenia, 20.4, 12.0% for leukopenia, 13.0, 8.0% for bicytopenia and 5.6, 4.0% for pancytopenia[ncbi.nlm.nih.gov] Infant presented with pallor, jaundice and massive spleen. Laboratory tests revealed anaemia, thrombocytopenia and bilirubinemia.[ncbi.nlm.nih.gov] Common physical findings include jaundice, hepatosplenomagaly and pallor.[clinicaladvisor.com]

  • Autoimmune Hemolytic Anemia

    Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org] A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] An otherwise seemingly normal girl, who had developed limping at the age of 11 months old, referred to Namazi Hospital, Shiraz, Iran, due to pallor and latitude at the age[ncbi.nlm.nih.gov]

  • Promyelocytic Leukemia

    The patient was treated with all-trans retinoic acid under a diagnosis of APL with improvement of the bicytopenia.[ncbi.nlm.nih.gov] Fatigue, weakness, pallor, weight loss, dyspnea, and fever are the initial, nonspecific symptoms that patients usually present with.[symptoma.com] 90% according to one study. [5] [4] [6] Contents Signs and symptoms Edit The symptoms tend to be similar to AML in general with the following being possible symptoms: [7] Bicytopenia[en.m.wikipedia.org]

  • Primary Myelofibrosis

    Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Skin pallor (caused by anemia) may also be noticeable.[aoporphan.com]

  • Acute Erythroblastic Leukemia

    The initial diagnoses were chronic myeloid leukemia in two, myelodysplastic syndrome in nine including four cases of Down syndrome, pancytopenia or bicytopenia in three, and[jstage.jst.go.jp] Pallor, sometimes petechiae, bruising, gum and nose bleeding, hepatosplenomegaly, lymphadenopathy, retinal haemorrhage .[patient.info] Physical examination revealed pallor without any obvious distress apart from moderate dyspnea. There was no palpable lymphadenopathy or hepatosplenomegaly.[ispub.com]

  • Severe Aplastic Anemia

    There is usually a waxy pallor, and hemorrhages occur in the mucous membranes, skin, and other organs.[britannica.com] Physical findings : Anemia with fatigue and pallor, bruising, petechiae (non-raised hemorrhage in the skin or in a membrane), and bleeding gums.[secure.ssa.gov] Low red cell count (anemia) can cause: Fatigue Pallor (paleness) Rapid heart rate Shortness of breath with exercise Weakness Lightheadedness upon standing Low white cell count[medlineplus.gov]

  • Sepsis

    The present patient met 5 of the HLH criteria: fever, splenomegaly, bicytopenia, hypertriglyceridemia and/or hypofibrinogenemia, and hyperferritinemia.[ncbi.nlm.nih.gov] 140 beats per minute or more Rapid heart rate: 130–139 beats per minute Skin Any Mottled or ashen appearance Cyanosis of skin, lips or tongue Non-blanching rash of skin Pallor[pathways.nice.org.uk]

  • Gaucher Disease

    Flashcards in Gaucher's disease Deck (11): What is Gaucher's disease? An autsomal recessive deficiency of acid Beta glucocerebrosidase most common glycogen storage disease 1 in 40,000 incidence most common in Ashkenazi Jewish origin what is the pathophysiology of Gaucher's disease? enzyme deficiency leads to[…][brainscape.com]

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