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300 Possible Causes for Bicytopenia, Partial Thromboplastin Time Increased

  • Gaucher Disease

    Flashcards in Gaucher's disease Deck (11): What is Gaucher's disease? An autsomal recessive deficiency of acid Beta glucocerebrosidase most common glycogen storage disease 1 in 40,000 incidence most common in Ashkenazi Jewish origin what is the pathophysiology of Gaucher's disease? enzyme deficiency leads to[…][]

  • Disseminated Intravascular Coagulation

    Clotting factors Pro Thrombin (PT) and Partial Thromboplastin Time (PTT) increases.[] , activated partial thromboplastin time, and thrombin time, due to consumption of clotting factors and inhibition of their function.[] […] time, and activated partial thromboplastin time, decreased plasma fibrinogen concentration, and activities of blood-coagulation factors II, V, VII, VIII, IX, X, XI, and XII[]

  • Coagulation Abnormalities

    It is likely that only with the increasing requests for prothrombin time and activated partial thromboplastin time are abnormal results noted.[] Higher incidence of prematurity, hyperbilirubinaemia and significant prolongation in partial thromboplastin time with kaolin (PTTK) and thrombin time (TT) values were observed[] thromboplastin time and decrease in prothrombin activity.[]

    Missing: Bicytopenia
  • Portal Cirrhosis

    Abstract Primary and secondary platelet aggregation in response to adenosine diphosphate was studied in 24 patients with portal (Laënnec) cirrhosis and compared with platelet aggregation in 14 normal subjects. In 12 patients with cirrhosis, platelet aggregation was diminished when compared to controls. Of the 12[…][]

    Missing: Bicytopenia
  • Hemophilia

    Plasma concentrations of emicizumab increased in a dose-dependent manner. Activated partial-thromboplastin times remained short throughout the study.[] During treatment, the activated partial-thromboplastin time remained short, and factor XIa–triggered thrombin generation was detected at each assessment in all three cohorts[] In cohort 3, in which the initial dose and subsequent doses were the same, the mean trough level gradually increased to 87.9 20.0 μg per milliliter by week 12 but did not[]

    Missing: Bicytopenia
  • Macronodular Cirrhosis

    OBJECTIVE: Patients with hepatocellular carcinoma (HCC) presenting with nonmicronodular or micronodular cirrhosis are usually treated by hepatectomy. The value of resection for patients with hepatitis B virus-related macronodular cirrhosis, however, remains unknown because of potentially fatal complications of this[…][]

    Missing: Bicytopenia
  • Liver Failure

    J Hum Genet. 2017 Jul;62(7):729-731. doi: 10.1038/jhg.2017.22. Epub 2017 Mar 9. Author information 1 APHP-CHU de Bicêtre, Biochemistry Department, 78, rue du Général Leclerc, Le Kremlin Bicêtre, France. 2 Pediatrics Department, Centre Hospitalier Haguenau, 64 Avenue du Pr Leriche, Haguenau, France. Abstract An isolated[…][]

    Missing: Bicytopenia
  • Isoniazid Hepatitis

    Abstract Two patients with liver failure secondary to isoniazid hepatotoxicity were successfully treated with orthotopic liver transplantation. A 49-year-old man received isoniazid prophylaxis for a positive tuberculin test, and a 60-year-old woman was treated for active pulmonary tuberculosis with isoniazid, rifampin,[…][]

    Missing: Bicytopenia
  • Systemic Lupus Erythematosus

    Tex Heart Inst J. 2017 Apr 1;44(2):147-149. doi: 10.14503/THIJ-16-5856. eCollection 2017 Apr. Abstract Libman-Sacks endocarditis, one of the most prevalent cardiac presentations of systemic lupus erythematosus, typically affects the aortic or mitral valve; tricuspid valve involvement is highly unusual. Secondary[…][]

    Missing: Bicytopenia
  • Acute Myelocytic Leukemia

    Abstract In a 42-year-old Caucasian female, acute myelocytic leukemia (M2) presented as occlusion of the distal aorta and right iliac artery. She died after 10 days of respiratory failure. At postmortem examination the aortic wall contained multiple thrombi composed of fibrin and leukemic cells. There was no evidence[…][]

    Missing: Bicytopenia

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