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15 Possible Causes for Bicytopenia, Pathological Fracture

  • Gaucher Disease

    fractures, and pyogenic osteomyelitis.[ncbi.nlm.nih.gov] But in adults, there are no reports of pathological femoral neck fractures with GD.[ncbi.nlm.nih.gov] BMD was low in 11 patients (50%); neither BMD nor HSA were associated with pathological fractures.[ncbi.nlm.nih.gov]

  • Bone Lymphoma

    We report a unique case of PBNHL with bicytopenia as the initial clinical manifestation in a Chinese.[caribbean.scielo.org] The treatment was designed to maintain efficacy but limit the risk of subsequent pathological fractures.[ncbi.nlm.nih.gov] Disease may be complicated at presentation by pathological fracture or spinal cord compression.[ncbi.nlm.nih.gov]

  • Paraneoplastic Syndrome

    A 40-year-old male with a history of peripheral neuropathy and erectile dysfunction presented with a pathological fracture of the neck of the femur, found to be a solitary[ncbi.nlm.nih.gov] More on polymyalgia rheumatica (PMR) as a paraneoplastic rheumatic syndrome in the elderly (bicytopenia and PMR preceding acute myeloid leukemia).[medical.nikkeibp.co.jp]

  • Evan's Syndrome

    The pattern of occurrence of bicytopenia can delay the diagnosis since it may be coincidental, sequential, or separate, and the time frame between episodes can range from[symptoma.com] Discussion The most common complications of multiple myeloma include anemia, hypercalcemia, pathologic fractures, renal failure and recurrent infections.[panafrican-med-journal.com]

  • Leukoerythroblastic Anemia

    However, pain and tenderness of affected bones, pathologic fractures, and hypercalcemia causing nausea, symptoms of anemia, muscle weakness, or stupor may bring patients to[medtextfree.wordpress.com] Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] Pathologic fractures of the bone and alterations of the bony cortex can indicate marrow expansion, in patients with thalassemia, some forms of leukemia and some myeloproliferative[cancertherapyadvisor.com]

  • Systemic Mastocytosis

    Rafii M, Firooznia H, Golimbu C, et al: Pathologic fracture in systemic mastocytosis. Clin Orthop 1983; 180:260-267. 6.[healio.com] Although the patient responded to the treatment, the relapse with splenomegaly and bicytopenia was observed after 10 months.[ncbi.nlm.nih.gov] In some patients, there is generalised osteoporosis with the risk of pathological fractures.[radiopaedia.org]

  • Acute Leukemia

    fracture Joint pain (must distinguish from arthritis and similar inflammatory conditions) Laboratory Usually elevated total leukocyte count, but could be normal or even reduced[pathologyoutlines.com] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Initial CBC showed bicytopenia, elevated blood urea, creatinine, and serum uric acid, while abdominal ultrasonography revealed bilateral renal enlargement.[ncbi.nlm.nih.gov]

  • Leukemoid Reaction

    Moreover, bone fracture of the joint socket was highly suspected. Magnetic resonance tomography (MRT) of her pelvis confirmed the pathological fracture.[jmedicalcasereports.biomedcentral.com] Infection induced hemophagocytic lymphohistiocytosis with a leukemoid reaction was suspected because of fever, splenomegaly and bicytopenia in conjunction with elevated serum[ncbi.nlm.nih.gov]

  • Bullous Pemphigoid

    For patients on azathioprine, two developed transaminitis and one had bicytopenia.[jddsjournal.org] […] and vertebral fractures, bone infarcts, and avascular necrosis leading to degenerative arthropathy).[ncbi.nlm.nih.gov] (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications (Erlenmeyer flask deformity, osteoporosis, lytic lesions, pathological[ncbi.nlm.nih.gov]

  • Paraneoplastic Polyneuropathy

    More on polymyalgia rheumatica (PMR) as a paraneoplastic rheumatic syndrome in the elderly (bicytopenia and PMR preceding acute myeloid leukemia).[medical.nikkeibp.co.jp] Radiographic examination of limbs may show loss of bone density, thinning of phalanges, pathologic fractures or neuropathic arthropathy.[aafp.org]

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