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34 Possible Causes for Bicytopenia, Stomatitis

  • Severe Aplastic Anemia

    Patients may tend to contract stomatitis, gingivitis, upper respiratory infection or pneumonia, among others.[] SAA patients may thus present with any type of infection, most commonly with stomatitis and gingivitis, upper respiratory infection, pneumonia, and urinary tract infection[]

  • Pancytopenia

    If more than one of the blood cells is low then the condition is called as bicytopenia.[] General examination  Eye examination: retinal hemorrhage leukemic infiltrations  oral examination : oral petechaie stomatitis / chelitis gum hyperplasia oral candidiasis[] If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.[]

  • Agranulocytosis

    Since there was a possibility of autoimmune etiology for bicytopenia, rheumatology opinion was sought following which CANCA (cytoplasm antineutrophil cytoplasmic antibodies[] Stomatitis, gingivitis, perirectal inflammation, colitis, sinusitis, paronychia, and otitis media often occur.[] A semisolid or liquid diet may be necessary during acute stomatitis or esophagitis, and topical analgesics (eg,viscous lidocaine ) may be needed to minimize discomfort.[]

  • Familial Neutropenia

    RCUD and MDS-U categories in 196 patients with less than 5% marrow blasts, Maassen et al. found 28% RA, 6% RT, 13% RN, 20% patients with no cytopenia, and 34% patients with bicytopenia[] Prepubertal periodontitis, oral ulceration, and angular stomatitis were the principal features.[] Yumiko Otsuka, Junko Matsuyama, Mieko Tomizawa, Tadashi Noda and Fumiko Iwano , Chronic benign neutropenia diagnosed due to severe stomatitis: a case report , Pediatric Dental[]

  • Drug-induced Neutropenia

    […] ne-ah ] diminished numbers of neutrophils in the blood. cyclic neutropenia a chronic form marked by regular, periodic episodic recurrences, associated with malaise, fever, stomatitis[] Bicytopenia: adverse effect of risperidone. Current Psychiatry. 2014;13(4):E1. 5. Meylan C, Bondolfi G, Aubert AC, Baumann P.[] Stomatitis, gingivitis, perirectal inflammation, colitis, sinusitis, paronychia, and otitis media often occur.[]

  • Drug-induced Bone Marrow Suppression

    Early forms of myelodysplastic syndrome initially can manifest as a single cytopenia or, more often, as a bicytopenia.[] Areas of stomatitis and skin infections should be treated with local cleaning, antisepsis, and dental care.[] Gastrointestinal effects include stomatitis (sores at the corners of the mouth); nausea and vomiting and rarely diarrhea.[]

  • Paraneoplastic Syndrome

    More on polymyalgia rheumatica (PMR) as a paraneoplastic rheumatic syndrome in the elderly (bicytopenia and PMR preceding acute myeloid leukemia).[] Anti-CD20 monoclonal antibody (rituximab) for refractory erosive stomatitis secondary to CD20( ) follicular lymphoma-associated paraneoplastic pemphigus.[]

  • Mantle Cell Lymphoma

    ) Muscle spasms Nausea Tiredness Mouth sores (stomatitis) Pneumonia Bruising Muscle spasms Diarrhea Nausea Diarrhea is a common side effect in people who take IMBRUVICA .[] Case report: A 64-year-old male initially presented with fatigue, splenomegaly, and bicytopenia.[] Bruising Muscle and bone pain Tiredness Rash Fever Nausea The most common side effects of IMBRUVICA in adults with cGVHD include: Tiredness Bruising Diarrhea Mouth sores (stomatitis[]

  • Acute Leukemia

    A 43-year-old female presented with leukocytosis and bicytopenia.[] Acute leukemia is characterized by fatigue, headache, sore throat, and dyspnea, followed by symptoms of acute tonsillitis, stomatitis, bleeding from the mucous membranes of[] Initial CBC showed bicytopenia, elevated blood urea, creatinine, and serum uric acid, while abdominal ultrasonography revealed bilateral renal enlargement.[]

  • Bullous Pemphigoid

    For patients on azathioprine, two developed transaminitis and one had bicytopenia.[] The third patient developed the same blistering lesions shortly after herpetic stomatitis.[] […] skin lesions not attributable to more common skin disorder Unexplained recurring pruritus, erythroderma, eczema, urticaria, desquamative gingivitis, or mucositis (including stomatitis[]

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