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96 Possible Causes for Bicytopenia, Thrombocytopenia

  • Gaucher Disease

    KEYWORDS: GBA gene mutation; Gaucher cells; thrombocytopenia; type 1 Gaucher disease[ncbi.nlm.nih.gov] Abstract Gaucher disease is a common inborn error of metabolism leading to widespread chronic inflammation and often thrombocytopenia.[ncbi.nlm.nih.gov] Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications (Erlenmeyer flask deformity, osteoporosis[ncbi.nlm.nih.gov]

  • Severe Aplastic Anemia

    She recovered completely, but her thrombocytopenia persisted. Six weeks later she became pancytopenic. A bone marrow aspirate and biopsy showed severe aplastic anemia.[ncbi.nlm.nih.gov] Anemia most frequently causes fatigue, headaches and dizziness; thrombocytopenia provokes a tendency to bleed.[symptoma.com] Stable mixed chimerism and mild thrombocytopenia, but no active hepatitis continued. At age 13, abdominal pain was a sign of massive tumor.[ncbi.nlm.nih.gov]

  • Pancytopenia

    […] mm(3), and severe thrombocytopenia as thrombocyte counts below 20,000/mm(3).[ncbi.nlm.nih.gov] If more than one of the blood cells is low then the condition is called as bicytopenia.[ncbi.nlm.nih.gov] If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.[en.wikipedia.org]

  • Disseminated Intravascular Coagulation

    Although thrombocytopenia is one of the major features of TAFRO syndrome, complications of disseminated intravascular coagulation (DIC) are not common.[ncbi.nlm.nih.gov] All three patients had chronic thrombocytopenia prior to developing an endoleak as did the four reported cases in the literature.[ncbi.nlm.nih.gov] With the increased use of rituximab, there is an increase incidence of cytopenias, most commonly thrombocytopenia and leucopenia.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov] Progression from bicytopenia to pancytopenia or a new episode of bicytopenia or pancytopenia after recovery was not considered as a first progression to bicytopenia or pancytopenia[bloodjournal.hematologylibrary.org] This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria. [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov]

  • Leukoerythroblastic Anemia

    Acute Erythroblastic Leukemia Anemia, X-Linked, without Thrombocytopenia aplastic anemia Aplastic Anemia, Idiopathic Bone Marrow Failure Syndromes chronic myeloid leukemia[rgd.mcw.edu] Pancytopenia was seen in 9.55% (17) cases and bicytopenia in 50.5% (90) patients.[jahjournal.org] […] who presented seven years following apparently successful surgery and adjuvant chemo-radio-therapy, with blood film findings of microangiopathic hemolytic anemia (MAHA), thrombocytopenia[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] 2017) Age – median is 65-70 Sex – M F Classification Classification of MDS, Subtypes Subtype Blood Bone Marrow MDS cytopenias with single lineage dysplasia Unicytopenia or bicytopenia[arupconsult.com] Non-reportable disorder s include: Anemia, leukopenia and thrombocytopenia.[seer.cancer.gov]

  • Drug-induced Bone Marrow Suppression

    The phenytoin was replaced by carbamazepine and the patient subsequently developed erythroid hypoplasia, neutropenia and persistent thrombocytopenia.[karger.com] Early forms of myelodysplastic syndrome initially can manifest as a single cytopenia or, more often, as a bicytopenia.[emedicine.medscape.com] Thrombocytopenia: Thrombocytopenia refers to a deficiency of platelets. A low level of platelets can result in bruising and heavy bleeding.[verywell.com]

  • Acute Leukemia

    A 29-year-old woman was admitted with thrombocytopenia, blast-like cells in the peripheral blood and a coagulation disorder.[ncbi.nlm.nih.gov] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Improving prevention of thrombosis appears a major goal in patients whose frequent conditions of thrombocytopenia impede an adequate delivery of anticoagulant therapy.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com] The main adverse effects of ruxolitinib are anemia and thrombocytopenia.[merck.com]

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